LMR GEORGETTE PMHNP COMPREHENSIVE EXAM 2026
QUESTIONS AND ANSWERS RATED A+
✔✔Monoamines - ✔✔dopamine, norepinephrine, serotonin, epinephrine
✔✔amino acids - ✔✔Glutamate and GABA
✔✔Cholinergic - ✔✔acetylcholine and neuropeptides
✔✔Brain Changes in Alzheimer's Disease - ✔✔amyloid plaques and neurofibrillary
tangles
✔✔Increased and decreased acetylcholine - ✔✔Increased- parkinson's
Decreased-alzheimers
✔✔Where is Norepinephrine produced? - ✔✔locus coeruleus
✔✔Where is serotonin produced? - ✔✔raphe nuclei
✔✔Where is epinephrine produced? - ✔✔adrenal glands
✔✔Where is dopamine produced? - ✔✔substantia nigra and ventral tegmental area
✔✔Where is GABA synthesized? - ✔✔limbic system
✔✔s/s of acute dystonia - ✔✔Severe spasm of the tongue, neck, eyes, face and back;
laryngeal spasms (mutism)
✔✔Akathisia - ✔✔motor restlessness
✔✔Parkinonism s/s - ✔✔slouched posture, shuffling gait, rigid, bradykinesia, tremors at
rest, pin-rolling
✔✔tardive dyskinesia - ✔✔involuntary movements of the facial muscles, tongue, and
limbs, protrusion of tongue, smacking lips
✔✔Aims - ✔✔abnormal involuntary movement scale
✔✔Neurotransmitters autism - ✔✔gaba, serotonin, glutamate
✔✔mood disorder neurotransmitters - ✔✔norepinephrine and serotonin
✔✔bipolar neurotransmitters - ✔✔increased glutamate
, ✔✔Anxiety neurotransmitters - ✔✔increased norepinephrine and
decreased GABA
✔✔OCD neurotransmitters - ✔✔decreased serotonin
✔✔Parkinson's neurotransmitters - ✔✔increased acetylcholine and decreased
dopamine
✔✔ADHD neurotransmitters - ✔✔decrease in dopamine and norepinephrine
✔✔Tourette's Neurotransmitters - ✔✔dopamine, serotonin, GABA, and glutamate
✔✔What to prescribe for Tourette's - ✔✔Risperdal
✔✔Substance abuse neurotransmitters - ✔✔decrease in opioid neuropeptides
✔✔Alcohol abuse neurotransmitters - ✔✔increase in GABA and dopamine and
decrease in serotonin
✔✔Depression neurotransmitters - ✔✔decrease in serotonin, dopamine, and
norepinephrine
✔✔sleep neurotransmitters - ✔✔low serotonin causes insomnia (Melatonin is pre-
cursor)
✔✔Schizophrenia neurotransmitters - ✔✔increased dopamine and decreased serotonin
✔✔negative symptoms of schizophrenia - ✔✔disturbance of affect, blunting (severe
reduction in the intensity of affect expression), flat affect, inappropriate affect (might
laugh hysterically while describing someones death)
✔✔positive symptoms of schizophrenia - ✔✔Delusions of reference, delusions of
persecution, delusions of grandeur, thought broadcasting, though insertion,
hallucinations, disorganized thought, disorganized behavior, catatonia
✔✔Side effects of atypical antipsychotics - ✔✔Risk of metabolic syndrome: increased
weight, blood glucose, triglycerides, and insulin resistance
✔✔Zyprexa (Olanzapine) side effect - ✔✔Excessive weight gain
✔✔Seroquel side effects - ✔✔weight gain and sedation; cataracts (assess with slit
lamp)
✔✔Thorazine (chlorpromazine) - ✔✔corneal deposits
QUESTIONS AND ANSWERS RATED A+
✔✔Monoamines - ✔✔dopamine, norepinephrine, serotonin, epinephrine
✔✔amino acids - ✔✔Glutamate and GABA
✔✔Cholinergic - ✔✔acetylcholine and neuropeptides
✔✔Brain Changes in Alzheimer's Disease - ✔✔amyloid plaques and neurofibrillary
tangles
✔✔Increased and decreased acetylcholine - ✔✔Increased- parkinson's
Decreased-alzheimers
✔✔Where is Norepinephrine produced? - ✔✔locus coeruleus
✔✔Where is serotonin produced? - ✔✔raphe nuclei
✔✔Where is epinephrine produced? - ✔✔adrenal glands
✔✔Where is dopamine produced? - ✔✔substantia nigra and ventral tegmental area
✔✔Where is GABA synthesized? - ✔✔limbic system
✔✔s/s of acute dystonia - ✔✔Severe spasm of the tongue, neck, eyes, face and back;
laryngeal spasms (mutism)
✔✔Akathisia - ✔✔motor restlessness
✔✔Parkinonism s/s - ✔✔slouched posture, shuffling gait, rigid, bradykinesia, tremors at
rest, pin-rolling
✔✔tardive dyskinesia - ✔✔involuntary movements of the facial muscles, tongue, and
limbs, protrusion of tongue, smacking lips
✔✔Aims - ✔✔abnormal involuntary movement scale
✔✔Neurotransmitters autism - ✔✔gaba, serotonin, glutamate
✔✔mood disorder neurotransmitters - ✔✔norepinephrine and serotonin
✔✔bipolar neurotransmitters - ✔✔increased glutamate
, ✔✔Anxiety neurotransmitters - ✔✔increased norepinephrine and
decreased GABA
✔✔OCD neurotransmitters - ✔✔decreased serotonin
✔✔Parkinson's neurotransmitters - ✔✔increased acetylcholine and decreased
dopamine
✔✔ADHD neurotransmitters - ✔✔decrease in dopamine and norepinephrine
✔✔Tourette's Neurotransmitters - ✔✔dopamine, serotonin, GABA, and glutamate
✔✔What to prescribe for Tourette's - ✔✔Risperdal
✔✔Substance abuse neurotransmitters - ✔✔decrease in opioid neuropeptides
✔✔Alcohol abuse neurotransmitters - ✔✔increase in GABA and dopamine and
decrease in serotonin
✔✔Depression neurotransmitters - ✔✔decrease in serotonin, dopamine, and
norepinephrine
✔✔sleep neurotransmitters - ✔✔low serotonin causes insomnia (Melatonin is pre-
cursor)
✔✔Schizophrenia neurotransmitters - ✔✔increased dopamine and decreased serotonin
✔✔negative symptoms of schizophrenia - ✔✔disturbance of affect, blunting (severe
reduction in the intensity of affect expression), flat affect, inappropriate affect (might
laugh hysterically while describing someones death)
✔✔positive symptoms of schizophrenia - ✔✔Delusions of reference, delusions of
persecution, delusions of grandeur, thought broadcasting, though insertion,
hallucinations, disorganized thought, disorganized behavior, catatonia
✔✔Side effects of atypical antipsychotics - ✔✔Risk of metabolic syndrome: increased
weight, blood glucose, triglycerides, and insulin resistance
✔✔Zyprexa (Olanzapine) side effect - ✔✔Excessive weight gain
✔✔Seroquel side effects - ✔✔weight gain and sedation; cataracts (assess with slit
lamp)
✔✔Thorazine (chlorpromazine) - ✔✔corneal deposits
