kHTABLEHOFHCONTENT
ChapterH 1:H Pharmacokinetics
ChapterH2:HDrug–
ReceptorHInteractionsHandHPharmacodynamicsH ChapterH3:H TheH
AutonomicHNervousHSystem
ChapterH4:HCholinergicHAgonistsHC
hapterH5:HCholinergicHAntagonistsH
ChapterH6:HAdrenergicHAgonistsHC
hapterH7:HAdrenergicHAntagonists
ChapterH8:HDrugsHforHNeurodegenerativeHDiseasesHC
hapterH9:HAnxiolyticHandHHypnoticHDrugs
ChapterH10:HAntidepressantsHChap
terH11:HAntipsychoticHDrugsHChapt
erH12:HDrugsHforHEpilepsyHChapter
H13:HAnesthetics
ChapterH 14:H Opioids
ChapterH15:HDrugsHofHAbuseHChap
terH16:HCNSHStimulantsHChapterH1
7:HAntihypertensivesHChapterH18:H
Diuretics
ChapterH 19:H HeartH Failure
ChapterH20:HAntiarrhythmicsHChapt
erH21:HAntianginalHDrugs
ChapterH22:HAnticoagulantsHandHAntiplateletHAgents
H ChapterH23:HDrugsHforHHyperlipidemia
ChapterH24:HPituitaryHandHThyroidH
ChapterH25:HDrugsHforHDiabetes
ChapterH26:HEstrogensHandHAndrogensHChap
terH27:HAdrenalHHormones
ChapterH 28:H DrugsH forH Obesity
ChapterH29:HDrugsHforHDisordersHofHtheHRespiratoryHSystemH Ch
apterH30:HAntihistamines
ChapterH31:HGastrointestinalHandHAntiemeticHDrugsH
ChapterH32:HDrugsHforHUrologicH Disorders
ChapterH 33:H DrugsH forH Anemia
ChapterH34:HDrugsHforHDermatologicHDisordersHCha
pterH35:HDrugsHforHBoneHDisorders
ChapterH36:HAnti-
inflammatory,HAntipyretic,HandH AnalgesicHAgentsH ChapterH37:H Principl
esHofH AntimicrobialH Therapy
ChapterH 38:H CellH WallH Inhibitors
ChapterH 39:H ProteinH SynthesisH Inhibitors
ChapterH40:HQuinolones,HFolicHAcidH Antagonists,H andH UrinaryH TractHAntisepticsHCh
apterH41:HAntimycobacterialHDrugs
ChapterH42:HAntifungalHDrugsHCha
pterH43:HAntiprotozoalHDrugsHChap
terH44:HAnthelminticHDrugsHChapte
rH45:HAntiviralHDrugs
ChapterH 46:H AnticancerH Drugs
ChapterH47:HImmunosuppressantsH
ChapterH48:HClinicalHToxicology
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,3. TheHnurseHisHteachingHaHpatientHwhoHwillHbeHdischargedHhomeHwithHaHprescriptionHforHanHenteri
c-HcoatedHtablet.HWhichHstatementHbyHtheHpatientH indicatesHunderstandingHofHtheHteaching?
a. IHmayHcrushHtheHtabletHandHputHitHinHapplesauceHtoHimproveHabsorption.
b. IHshouldH consumeHacidicHfoodsHtoHenhanceHabsorptionHofHthisHmedication.
c. IH shouldH expectH aHdelayHinHonsetH ofHtheHdrugsHeffectsHafterHtakingHtheHtablet.
d. IHshouldHtakeHthisHmedicationHwithHhigh-
fatHfoodsHtoHimproveHitsHaction.HANS:HC
Enteric-
coatedHtabletsHresistHdisintegrationHinHtheHacidicHenvironmentHofHtheHstomachHandHdisintegrateHw
henHtheyHreachHtheHsmallHintestine.HThereHisHusuallyHsomeHdelayHinHonsetHofHactionsHafterHtakingHt
heseHmedications.HEnteric-
coatedHtabletsHshouldHnotHbeHcrushedHorHchewed,HwhichHwouldHalterHtheHtimeHandHlocationHofHabs
orption.HAcidicHfoodsHwillHnotHenhanceHtheHabsorptionHofHtheHmedication.HTheHpatientHshouldHnot
toHeatHhigh-fatHfoodHbeforeHingestingHanHenteric-coatedHtablet,HbecauseHhigh-
H
fatHfoodsHdecreaseHtheHabsorptionHrate.
DIF:HCOGNITIVEHLEVEL:HApplyingH(Application)HREF:HdmH3HT
OP:HNURSINGHPROCESS:HNursingHIntervention
MSC:HNCLEX:HPhysiologicalHIntegrity:HPharmacologicalHandHParenteralHTherapies
4. AHpatientHwhoHisHnewlyHdiagnosedHwithHtypeH1HdiabetesHmellitusHasksHwhyHinsulinHmustHbeH
givenHbyHsubcutaneousHinjectionHinsteadHofHbyHmouth.HTheHnurseHwillHexplainHthatHthisHisHbecau
se
a. absorptionHisH diminishedH byHtheHfirst-passHeffectsHinHtheHliver.
b. absorptionHisHfasterHwhenHinsulinHisHgivenHsubcutaneously.
c. digestiveHenzymesHinHtheHgastrointestinalHtractHpreventHabsorption.
d. theHoralHformHisHlessHpredictableHwithHmoreHadverseHeffects
.HANS:HC
Insulin,HgrowthHhormones,HandHotherHprotein-
basedHdrugsHareHdestroyedHinHtheHsmallHintestineHbyHdigestiveHenzymesHandHmustHbeHgivenHparen
terally.HBecauseHinsulinHisHdestroyedHbyHdigestiveHenzymes,HitHwouldHnotHmakeHitHtoHtheHliverHfor
metabolismHwithHaHfirst-
H
passHeffect.HSubcutaneousHtissueHhasHfewerHbloodHvessels,HsoHabsorptionHisHslowerHinHsuchHtissue
.HInsulinHisHgivenHsubcutaneouslyHbecauseHitHisHdesirableHtoHhaveHitHabsorbHslowly.
DIF:HCOGNITIVEHLEVEL:HUnderstandingH(Comprehension)HREF:HdmH3HT
PageH 2H ofH 507
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, OP:HNURSINGHPROCESS:HNursingHIntervention:HPatientHTeaching
MSC:HNCLEX:HPhysiologicalHIntegrity:HPharmacologicalHandHParenteralHTherapies
PageH 3H ofH 507
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