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APEA 3P 2026|COMPLETE EXAM
WITH VERIFIED ANSWERS AND
RATIONALES 2026
Erythema Migrans (early Lyme disease): DX - correct-answer -Dx: • First step is
enzyme immunoassay (EIA) also knows as ELISA if negative no further testing
needed. If positive confirm with Western Blot test (aka indirect
immunofluorescence assay (IFA) for Borrelia Burgdorferi
1. Enzyme immunoassay
2. western blot test (immunoflurorescence assay/ IFA)
Exam Tip: E before I
Will have increased ESR
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Erythema Migrans (early Lyme disease): TX - correct-answer -Doxycycline is
always first line for all ages
100 mg BID x 10-21 days
Remove ticks by grasping with tweezers or forceps close to the skin and pulling
gently with steady pressure. After removing the tick, clean area with rubbing
alcohol, iodine scrub, or soap and water. Dispose of the tick by flushing it into the
toilet
Tick repellant skin use - correct-answer -DEET
Tick repellant clothing use - correct-answer -Permethrin
Brown Recluse Spider Bite: SX - correct-answer -• Fever, chills • Nausea and
Vomiting • Located in the arms, upper legs, or the trunk • Bitten area becomes
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swollen, red, and tender, or can be painless • Blisters appear within 24-48 hours •
Necrotic in center, which kills the tissue
**can be painless
Brown Recluse Spider Bite treatment - correct-answer -Treatment: • Ice packs to
wound as the cold inactivates the toxin • Treat like cellulitis of the skin •
Antibiotic ointment at first and watch
Skin lesions - correct-answer -primary skin lesions
Macule Vesicle Papule MVP Size: <1 CM
Macule - correct-answer -Flat, nonpalpable, but visually distinct areas on the skin
surface with color different from the person's normal skin; less than 1 cm
FRECKLE
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Vesicle - correct-answer -elevated, raised lesion filled with serous fluid (herpetic
lesions)
Papule - correct-answer -palpable solid lesion (acne, moles)
primary skin lesions >1cm in size - correct-answer -Nodule
Plaque
Bullae (Blister)
Pustule
Wheal
Nodule - correct-answer -raised solid lesion (BCC)
Plaque - correct-answer -solid raised lesion with flat top (psoriasis)
APEA 3P 2026|COMPLETE EXAM
WITH VERIFIED ANSWERS AND
RATIONALES 2026
Erythema Migrans (early Lyme disease): DX - correct-answer -Dx: • First step is
enzyme immunoassay (EIA) also knows as ELISA if negative no further testing
needed. If positive confirm with Western Blot test (aka indirect
immunofluorescence assay (IFA) for Borrelia Burgdorferi
1. Enzyme immunoassay
2. western blot test (immunoflurorescence assay/ IFA)
Exam Tip: E before I
Will have increased ESR
,2|Page
Erythema Migrans (early Lyme disease): TX - correct-answer -Doxycycline is
always first line for all ages
100 mg BID x 10-21 days
Remove ticks by grasping with tweezers or forceps close to the skin and pulling
gently with steady pressure. After removing the tick, clean area with rubbing
alcohol, iodine scrub, or soap and water. Dispose of the tick by flushing it into the
toilet
Tick repellant skin use - correct-answer -DEET
Tick repellant clothing use - correct-answer -Permethrin
Brown Recluse Spider Bite: SX - correct-answer -• Fever, chills • Nausea and
Vomiting • Located in the arms, upper legs, or the trunk • Bitten area becomes
,3|Page
swollen, red, and tender, or can be painless • Blisters appear within 24-48 hours •
Necrotic in center, which kills the tissue
**can be painless
Brown Recluse Spider Bite treatment - correct-answer -Treatment: • Ice packs to
wound as the cold inactivates the toxin • Treat like cellulitis of the skin •
Antibiotic ointment at first and watch
Skin lesions - correct-answer -primary skin lesions
Macule Vesicle Papule MVP Size: <1 CM
Macule - correct-answer -Flat, nonpalpable, but visually distinct areas on the skin
surface with color different from the person's normal skin; less than 1 cm
FRECKLE
, 4|Page
Vesicle - correct-answer -elevated, raised lesion filled with serous fluid (herpetic
lesions)
Papule - correct-answer -palpable solid lesion (acne, moles)
primary skin lesions >1cm in size - correct-answer -Nodule
Plaque
Bullae (Blister)
Pustule
Wheal
Nodule - correct-answer -raised solid lesion (BCC)
Plaque - correct-answer -solid raised lesion with flat top (psoriasis)
