COMPREHENSIVE PRACTICE QUESTIONS
AND VERIFIED CORRECT ANSWERS
ADVANCED PHARMACOLOGY,
PRESCRIBING PRINCIPLES, DRUG
THERAPY MANAGEMENT, CLINICAL
DECISION MAKING AND NURSE
PRACTITIONER FINAL EXAM STUDY
GUIDE GRADE A+ STUDY RESOURCE
B2 agonist monitoring - CORRECT ANSWER -FEV1, home PEF at each
clinical encounter
Inhaled Corticosteroids (ICS) - CORRECT ANSWER -fluticasone
mometasone
budesonide
beclomethasone
pref for persistent asthma
need consistent daily use for optimal effect (NOT PRN)
,CONTRAINDICATED WITH CANDIDA ALBICANS, BUT OK WITH
CANDIDIASIS
ICS baseline data - CORRECT ANSWER -respiratory system data, PFT's,
baseline height needed for children, bone density for adults or anyone at
risk
ics monitori - CORRECT ANSWER -FEV1 and PEEK flow, oral candidiasis
(spacers can help) and ok to give antifungal medications, glaucoma, adrenal
insufficiency, in children, growth >6months
methylxa - CORRECT ANSWER -Theophylline
bronchodilation to decrease intensity and frequency of moderate to severe
asthma attacks, and control COPD exacerbations
Theophylline baseline data/monitoring - CORRECT ANSWER -FEV1.
Monitor FEV1 and severity of attacks, HR/rythm, monitor ECG if
necessary, monitor levels 5-15 ng/mL toxicity looks like metabolic
disturbances including acidosis, n/v seizures, dysrhythmia
Theophylline contraindications (methylxanthine) - CORRECT ANSWER -
Seizure, cardiac (exacerbate dysrythmia), peptic ulcers, renal, or liver
disorders (increase toxicity)
theophylline int - CORRECT ANSWER -Caffeine (dysrhythmia)
Tobacco and marijuana (increases clearance)
, Cimetidine/phenobarb/rifampin (increase clearance)
Fluoroquinolone antibiotics (decrease clearance)
anticholinergics - CORRECT ANSWER -reduce bronchospasm (ipratropium,
dicyclomine) blocks a neurotransmitter called acetylcholine, released by
muscarinic receptor, which, in lungs, allows smooth muscle to relax
reduce secretions
used in asthma, copd, emphysema
liquid aerosol or metered dose inhailer
contraindications anticholinergics - CORRECT ANSWER -Glaucoma, BPH,
hyperplasia, renal disorders, urinary bladder neck obstruction
-Breastfeeding women
Leukotrine Re - CORRECT ANSWER -Montelukast (Singulair) inflammatory
mediator, reduces bronchoconstriction,
asthma and exercise induced bronchospasm in adults
2 years> seasonal allergies
6months year-round allergies
LRA black box - CORRECT ANSWER -in children: aggression, anxiety,
insomnia, suicidal ideation, should be stopped immediately
mast cell stabilizers - CORRECT ANSWER -Cromolyn (alternative therapy)
exercise induced asthma