VERIFIED CORRECT ANSWERS
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Are adverse drug reactions preventable? - CORRECT ANSWER-yes
where do adverse drug reactions occur? - CORRECT ANSWER-hospital or nursing home setting
what does adverse drug reactions include? - CORRECT ANSWER-med errors
adverse drug effects
allergic and idiosyncratic type reactions
Does the FDA mandate that ADRs are reported? - CORRECT ANSWER-no
What does polypharmacy involve? - CORRECT ANSWER-Multiple health care providers for care
usig multiple medications
using several pharmacies for prescription filling
,Types of angiotension converting enzyme inhibitors (ACEIS) - CORRECT ANSWER-lisinopril
captopril
enalapril
ramipril
benazepril
fosinopril
How do ACEIS work? - CORRECT ANSWER-reduce blood pressure by suppressing the release of
angiotensin converting enzyme
What are the important side effects of ACE inhibitors - CORRECT ANSWER-cough
angioedema
What should you do if angioedema develops while on ACEI's? - CORRECT ANSWER-
discontinue medication
What are the angiotension II receptor blocking agents (ARBS) - CORRECT ANSWER-
Candesartan (Atacand)
Eprosartan (teveten)
Irbesartan (avapro)
losartan (cozaar)
telmisartan (micardis)
valsartan (diovan)
How do ARBs work? - CORRECT ANSWER-reduce blood pressure by blocking angiotensin II
receptors
,90% of cases of htn are? - CORRECT ANSWER-essential primary htn
What is secondary hypertension caused by? - CORRECT ANSWER-chonic renal failure
How can nitroglycerin be administered? - CORRECT ANSWER-IV
SL
topical ointment
transdermal patch
What are nitrates contraindicated with? - CORRECT ANSWER-PDE-5 inhibitors
(sildenafil/vardenafil)
When there is coexisting heart failure in a patient, what is the antiarrythmic of choice? -
CORRECT ANSWER-amiodarone
What happens with Alpha-1 adrenergic stimulation? - CORRECT ANSWER-vasoconstriction and
increased BP
What happens with Alpha-1 adrenergic blockade? - CORRECT ANSWER-vasodilation
reduced BP
Beta-1 adrenergic stimulation by beta agonists results in? - CORRECT ANSWER-increased heart
rate
increased blood pressure
increased cardiac output
Beta-1 adrenergic blockade results in? - CORRECT ANSWER-reduced heart rate
, reduced BP
reduced CO
Left heart failure causes? - CORRECT ANSWER-reduced delivery of oxygenated blood to the
body tissues
Right heart failure is associated with? - CORRECT ANSWER-pulmonary disease and increased
pulmonary vascular resistance
What drug relieves heart failure symptoms but does not reduce mortality? - CORRECT
ANSWER-furosemide
Loop diuretics like furosemide are and can cause what? - CORRECT ANSWER-potent diuretics
can cause diuretic resistance and hypokalemia
Where do loop diuretics work? - CORRECT ANSWER-work on receptors in the thick ascending
loop of henle
What are examples of potassium sparing diuretics - CORRECT ANSWER-spironolactone,
triamterene
What phosphodiestrase inhibitor is used for acute heart failure? - CORRECT ANSWER-
milirinone
How do children diagnosed with the tetraology of fallot stop - CORRECT ANSWER-squatting
down (a compensatory mechanism)