Guyton and Hall Textbook of Medical Physiology (Guyton Physiology) 14th
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Edition
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Chapter 01:Functional Organization of the Human Body and Control of the —Internal
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Environment‖
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Hall: Guyton and Hall Textbook of Medical Physiology, 14th Edition
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MULTIPLE CHOICE FT L
1. Which of the following statements about homeostasis is incorrect?
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a. It refers to the maintenance of a stable internal environment for the body.
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b. Homeostatic mechanisms do not operate in diseases. FT L L
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c. Homeostasis requires integrated actions of the cells, tissues, organs, and multiple L
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nervous, hormonal, and local control systems. L
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d. Homeostatic compensations that begin after a major environmental challenge may FT L L
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contribute to abnormalities of body function. FT L FT L L
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ANS: F T L B
2. What is the most abundant type of cell in the human body?
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a. Neuron
b. Epithelial cell FT L
c. Red blood cell L
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d. White blood cell L
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e. Vascular smooth muscle cell L
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f. Skeletal muscle cell L
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ANS: F T L C
3. The most abundant substance in the human body and the approximate percentage of that
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a. Protein, 30% FT L
b. Protein, 60% FT L
c. Water, 30% L
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d. Water, 60% L
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e. Carbohydrate, 30% FT L
f. Carbohydrate, 60% FT L
ANS: F T L D
4. If the feedback gain of a control system is
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a. a negative feedback system capable of correcting 1/2 of the initial disturbance to
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the system. FT L
b. a negative feedback system capable of correcting 2/3 of the initial disturbance to
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the system. FT L
c. a negative feedback system capable of correcting 3/4 of the initial disturbance to
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, the system. FT L
d. a positive feedback system capable of correcting 1/2 of the initial disturbance to
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the system. FT L
e. a positive feedback system capable of correcting 2/3 of the initial disturbance to
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the system. FT L
f. a positive feedback system capable of correcting 3/4 of the initial disturbance to
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the system. FT L
ANS: F T L B
5. Which of the following substances has the highest extracellular fluid to intracellular fluid
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concentration ratio for most mammalian cells?
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a. Sodium ions FT L
b. Potassium ions FT L
c. Carbon dioxide L
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d. Glucose
e. Protein
ANS: F T L A
6. Exchange of substances between the cardiovascular system and the interstitial fluid occurs
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a. Arteries
b. Arterioles
c. Capillaries
d. Venules
e. Veins
ANS: F T L C
7. What is the approximate distance from the capillaries to most cells of the body?
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a. Less than 50 angstroms L
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b. Less than 50 microns L
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c. Less than 50 millimeters L
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d. Less than 100 angstroms L
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e. Less than 100 microns L
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f. Less than 100 millimeters L
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ANS: F T L A
8. When a person is at rest, how much time is required for the blood in the circulation to
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a. 1 second
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b. 1 minute
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c. 3 minutes
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d. 4 minutes
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e. 5 minutes
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ANS: F T L B
9. The type of control system that can sometimes cause instability and vicious cycles is
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, a. negative feedback. FT L
b. feed-forward control. L
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c. positive feedback. FT L
d. adaptive feedback. FT L
e. delayed negative feedback. L
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ANS: F T L C
10. Which of the following is an example of positive feedback in the body?
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a. Return of blood pressure toward normal after a hemorrhage L
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b. Generation of action potentials in nerves FT L L
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c. Increased respiration rate caused by accumulation of carbon dioxide in the blood FT L FT L FT L FT L L
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d. Decreased sympathetic nervous system activity that occurs in response to FT L FT L FT L FT L FT L L
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increased blood pressure L
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ANS: F T L B
11. Which of the following is an example of a —feed-forward‖ control system?
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a. The arterial baroreceptor system L
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b. The progressive nature of uterine contractions during childbirth
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c. Control of skeletal muscle movements by the brain FT L FT L FT L FTL FT L L
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d. Generation of an action potential L
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ANS: F T L C
12. Which of the following is an example of negative feedback?
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Example 1: Arterial baroreceptor control of blood pressure
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Example 2: Excitation of the respiratory center by increased blood carbon dioxide
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concentration
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Example 3: Hemorrhagic shock caused by severe blood loss
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a. Example 1 only FT L L
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b. Example 2 only FT L L
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c. Example 3 only FT L L
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d. Examples 1 and 2, but not 3 FT L L
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e. Examples 1, 2, and 3 FT L FT L L
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ANS: F T L D
Chapter 02: The Cell and Its Functions
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MULTIPLE CHOICE FT L
1. The most abundant cell membrane lipids are
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a. sphingolipids.
b. phospholipids.
c. cholesterol.
d. triglycerides.
e. sterols.
, ANS: F T L B
2. Organelles that neutralize drugs and toxins are L
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a. nuclei.
b. mitochondria.
c. lysosomes.
d. peroxisomes.
e. endoplasmic reticulum. FT L
ANS: F T L D
3. Use the terms in the following list to identify the cellular location for the steps involved in
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the synthesis and packaging of a secreted protein.
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—Initiation of translation‖ FT L FT L
a. Nucleolus
b. Nucleus
c. Agranular endoplasmic reticulum FT L L
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d. Granular endoplasmic reticulum L
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e. Golgi apparatus L
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f. Endosomes
g. Peroxisomes
h. Cytosol
ANS: F T L H
4. Use the terms in the following list to identify the cellular location for the steps involved in
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the synthesis and packaging of a secreted protein.
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—Protein sorting and packaging‖ FT L FT L FT L
a. Nucleolus
b. Nucleus
c. Agranular endoplasmic reticulum FT L L
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d. Granular endoplasmic reticulum L
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e. Golgi apparatus L
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f. Endosomes
g. Peroxisomes
h. Lysosomes
ANS: F T L E
5. Use the terms in the following list to identify the cellular location for the steps involved in
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the synthesis and packaging of a secreted protein.
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—Gene transcription‖
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a. Nucleolus
b. Nucleus
c. Agranular endoplasmic reticulum FT L L
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d. Granular endoplasmic reticulum L
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e. Golgi apparatus L
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f. Endosomes
g. Peroxisomes
h. Lysosomes