NSGl 552/l NSG552l Examl 1l –l
Psychopharmacologyl Review|l Wilkesl
(Latestl 2026/l 2027l Update)l 100%l
Verifiedl Questionsl &l Answersl |l Gradel A
Q:l MAOIs
Answer:
Phenelzinel (Nardil)
Tranylcyprominel (Parnate)
Isocarboxazidl (Marplan)
Q:l MAOIl mechanisml ofl action
Answer:
Deactivatel MOA-Al andl MOA-Bl (enzymesl neededl tol deactivatel 5HT,l DA,l tyramine)=l
increasesl thel numberl ofl neurotransmittersl inl thel synapses.
Q:l Speciall notel onl Phenelzine
Answer:
Phenelzinel hasl beenl shownl tol bel morel effectivethanl placebol forl MDDl w/l atypicall
features,l MDDw/l psychoticl featuresl andl sociall phobia
MAOI
, Q:l Antidepressantl withdrawal
Answer:
F=l Flul likel symptomsl (aches,l pains,l chills)
I=l Insomnia
N=l Nausea
I=l Imbalance
S=l Sensoryl disturbancel (tremors,l sensationl ofl electricall shock)
H=l Hyperarousal
Fluoxetinel andl Vortioxetinel leastl likely
Q:l SNRIs
Answer:
Venlafaxinel (Effexor)
Duloxetinel (Cymbalta)
Q:l Serotoninl Syndrome
Answer:
S=Shivering
H=Hyperreflexia/Myoclonicl jerks
Il =l Increasedl Templ (Fever)
V=l Vitalsl Instabilityl (l ↑↓BP;l ↑RR;l ↑HR)
E=l Encephalopathyl (l Confusion)
R=l Restlessness
S=l Sweatingl (l Diaphoresis)
Psychopharmacologyl Review|l Wilkesl
(Latestl 2026/l 2027l Update)l 100%l
Verifiedl Questionsl &l Answersl |l Gradel A
Q:l MAOIs
Answer:
Phenelzinel (Nardil)
Tranylcyprominel (Parnate)
Isocarboxazidl (Marplan)
Q:l MAOIl mechanisml ofl action
Answer:
Deactivatel MOA-Al andl MOA-Bl (enzymesl neededl tol deactivatel 5HT,l DA,l tyramine)=l
increasesl thel numberl ofl neurotransmittersl inl thel synapses.
Q:l Speciall notel onl Phenelzine
Answer:
Phenelzinel hasl beenl shownl tol bel morel effectivethanl placebol forl MDDl w/l atypicall
features,l MDDw/l psychoticl featuresl andl sociall phobia
MAOI
, Q:l Antidepressantl withdrawal
Answer:
F=l Flul likel symptomsl (aches,l pains,l chills)
I=l Insomnia
N=l Nausea
I=l Imbalance
S=l Sensoryl disturbancel (tremors,l sensationl ofl electricall shock)
H=l Hyperarousal
Fluoxetinel andl Vortioxetinel leastl likely
Q:l SNRIs
Answer:
Venlafaxinel (Effexor)
Duloxetinel (Cymbalta)
Q:l Serotoninl Syndrome
Answer:
S=Shivering
H=Hyperreflexia/Myoclonicl jerks
Il =l Increasedl Templ (Fever)
V=l Vitalsl Instabilityl (l ↑↓BP;l ↑RR;l ↑HR)
E=l Encephalopathyl (l Confusion)
R=l Restlessness
S=l Sweatingl (l Diaphoresis)
