HESI LPN-TO-ADN EXAM 200 ACTUAL QUESTIONS AND
CORRECT ANSWERS WITH RATIONALE LATEST 2026
ALREADY GRADED A+
200 questions covering the core content of the HESI LPN-to-ADN Entrance
Exam. The questions span dosage calculations (including IV rates,
conversions, and tablet dosages), reading comprehension, grammar and
punctuation, basic sciences (anatomy, physiology, and pathophysiology), and
critical thinking scenarios focused on safe patient handling, mobility, and fall
prevention. Each question includes a correct answer and a detailed rationale
explaining the clinical reasoning or mathematical principle behind it. The
questions are designed to reflect the actual exam's difficulty and subject
distribution, with no duplication of clinical scenarios, numerical values,
medications, or grammatical rules across the entire set.
1 A nurse is preparing to ambulate a patient with left-sided weakness. Where
should the nurse position the wheelchair?
A. Parallel to the bed on the patient's weak side
B. Parallel to the bed on the patient's strong side
C. At the foot of the bed
D. Facing away from the bed
Answer: B
Rationale: Positioning the wheelchair on the strong side allows the patient to pivot
toward the stronger leg and push up with the stronger arm, making the transfer
safer and more stable. Placing it on the weak side increases fall risk.
2 A patient weighs 180 pounds. How many kilograms is this? (Round to the
nearest tenth.)
A. 81.6 kg
B. 82.0 kg
C. 79.4 kg
D. 80.0 kg
Answer: A
Rationale: 1 kg = 2.2 lbs. 180 ÷ 2.2 = 81.818, rounded to 81.6 kg. This conversion
is essential for accurate medication dosing.
,3 Which word is used correctly in the sentence? "The patient's vital signs were
stable, ______ the nurse continued to monitor closely."
A. yet
B. so
C. because
D. although
Answer: B
Rationale: "So" indicates a logical result. The stability led to continued monitoring.
"Yet" implies contrast, "because" gives a cause, and "although" introduces a
concession.
4 The physician orders 500 mg of a medication. The available tablet is 250 mg.
How many tablets will you administer?
A. 1 tablet
B. 1.5 tablets
C. 2 tablets
D. 2.5 tablets
Answer: C
Rationale: 500 mg ÷ 250 mg/tablet = 2 tablets. This is a basic dosage calculation
requiring simple division.
5 In cellular respiration, which organelle is primarily responsible for producing
ATP?
A. Nucleus
B. Ribosome
C. Mitochondrion
D. Golgi apparatus
Answer: C
Rationale: Mitochondria are the powerhouses of the cell, generating ATP through
oxidative phosphorylation. The nucleus houses DNA, ribosomes synthesize
proteins, and the Golgi modifies and packages proteins.
6 A patient needs to be log-rolled. What is the primary purpose of this technique?
A. To allow the patient to sit up independently
B. To maintain spinal alignment during turning
C. To exercise the patient's abdominal muscles
D. To prevent pressure ulcers on the heels
Answer: B
,Rationale: Log-rolling keeps the spine in a straight, neutral position, which is
critical for patients with spinal injuries or post-spinal surgery to prevent further
damage.
7 What is the value of x: 3x + 7 = 22?
A. 3
B. 5
C. 7
D. 9
Answer: B
Rationale: Subtract 7 from both sides: 3x = 15. Divide by 3: x = 5. This tests basic
algebra skills needed for dosage calculations.
8 Choose the sentence with correct grammar.
A. The nurse went to the room and took they vital signs.
B. The nurse went to the room and took their vital signs.
C. The nurse went to the room and took them vital signs.
D. The nurse went to the room and took there vital signs.
Answer: B
Rationale: "Their" is the possessive pronoun correctly referring to the patients.
"They" is subjective, "them" is objective, and "there" indicates a place.
9 Which of the following is an example of active transport across a cell
membrane?
A. Diffusion of oxygen
B. Facilitated diffusion of glucose
C. The sodium-potassium pump
D. Osmosis of water
Answer: C
Rationale: The sodium-potassium pump uses ATP to move ions against their
concentration gradient, which defines active transport. The other options are
passive transport.
10 A patient has an order for heparin 8,000 units subcutaneously. The vial reads
10,000 units/mL. How many mL will you draw?
A. 0.8 mL
B. 1.0 mL
C. 1.2 mL
D. 0.6 mL
Answer: A
, Rationale: 8,000 units ÷ 10,000 units/mL = 0.8 mL. This is a straightforward ratio
and proportion calculation.
11 When transferring a patient from bed to stretcher using a draw sheet, what
action best protects the nurse's back?
A. Bending at the waist and pulling
B. Keeping the feet together and twisting
C. Bending at the knees and keeping the back straight
D. Reaching over the patient as far as possible
Answer: C
Rationale: Bending at the knees and keeping the back straight uses leg muscles and
maintains proper body mechanics, reducing the risk of back injury.
12 Read the passage: "The nurse observed that the wound was erythematous, with
moderate serosanguineous drainage. The edges were approximated, and there was
no foul odor." What does "erythematous" mean?
A. Swollen
B. Reddened
C. Warm
D. Painful
Answer: B
Rationale: Erythematous means redness of the skin or tissue, often indicating
inflammation or infection. The other options describe other signs.
13 A medication is available as 50 mg/2 mL. How many mL are needed for a 75
mg dose?
A. 2.5 mL
B. 3.0 mL
C. 3.5 mL
D. 4.0 mL
Answer: B
Rationale: Set up proportion: 50 mg/2 mL = 75 mg/x mL. Cross-multiply: 50x =
150, x = 3.0 mL.
14 Which sentence is grammatically correct?
A. The patient did not respond to the medication, which concerned the nurse.
B. The patient did not respond to the medication which concerned the nurse.
C. The patient did not respond to the medication, that concerned the nurse.
D. The patient did not respond to the medication that concerned the nurse.
Answer: A
CORRECT ANSWERS WITH RATIONALE LATEST 2026
ALREADY GRADED A+
200 questions covering the core content of the HESI LPN-to-ADN Entrance
Exam. The questions span dosage calculations (including IV rates,
conversions, and tablet dosages), reading comprehension, grammar and
punctuation, basic sciences (anatomy, physiology, and pathophysiology), and
critical thinking scenarios focused on safe patient handling, mobility, and fall
prevention. Each question includes a correct answer and a detailed rationale
explaining the clinical reasoning or mathematical principle behind it. The
questions are designed to reflect the actual exam's difficulty and subject
distribution, with no duplication of clinical scenarios, numerical values,
medications, or grammatical rules across the entire set.
1 A nurse is preparing to ambulate a patient with left-sided weakness. Where
should the nurse position the wheelchair?
A. Parallel to the bed on the patient's weak side
B. Parallel to the bed on the patient's strong side
C. At the foot of the bed
D. Facing away from the bed
Answer: B
Rationale: Positioning the wheelchair on the strong side allows the patient to pivot
toward the stronger leg and push up with the stronger arm, making the transfer
safer and more stable. Placing it on the weak side increases fall risk.
2 A patient weighs 180 pounds. How many kilograms is this? (Round to the
nearest tenth.)
A. 81.6 kg
B. 82.0 kg
C. 79.4 kg
D. 80.0 kg
Answer: A
Rationale: 1 kg = 2.2 lbs. 180 ÷ 2.2 = 81.818, rounded to 81.6 kg. This conversion
is essential for accurate medication dosing.
,3 Which word is used correctly in the sentence? "The patient's vital signs were
stable, ______ the nurse continued to monitor closely."
A. yet
B. so
C. because
D. although
Answer: B
Rationale: "So" indicates a logical result. The stability led to continued monitoring.
"Yet" implies contrast, "because" gives a cause, and "although" introduces a
concession.
4 The physician orders 500 mg of a medication. The available tablet is 250 mg.
How many tablets will you administer?
A. 1 tablet
B. 1.5 tablets
C. 2 tablets
D. 2.5 tablets
Answer: C
Rationale: 500 mg ÷ 250 mg/tablet = 2 tablets. This is a basic dosage calculation
requiring simple division.
5 In cellular respiration, which organelle is primarily responsible for producing
ATP?
A. Nucleus
B. Ribosome
C. Mitochondrion
D. Golgi apparatus
Answer: C
Rationale: Mitochondria are the powerhouses of the cell, generating ATP through
oxidative phosphorylation. The nucleus houses DNA, ribosomes synthesize
proteins, and the Golgi modifies and packages proteins.
6 A patient needs to be log-rolled. What is the primary purpose of this technique?
A. To allow the patient to sit up independently
B. To maintain spinal alignment during turning
C. To exercise the patient's abdominal muscles
D. To prevent pressure ulcers on the heels
Answer: B
,Rationale: Log-rolling keeps the spine in a straight, neutral position, which is
critical for patients with spinal injuries or post-spinal surgery to prevent further
damage.
7 What is the value of x: 3x + 7 = 22?
A. 3
B. 5
C. 7
D. 9
Answer: B
Rationale: Subtract 7 from both sides: 3x = 15. Divide by 3: x = 5. This tests basic
algebra skills needed for dosage calculations.
8 Choose the sentence with correct grammar.
A. The nurse went to the room and took they vital signs.
B. The nurse went to the room and took their vital signs.
C. The nurse went to the room and took them vital signs.
D. The nurse went to the room and took there vital signs.
Answer: B
Rationale: "Their" is the possessive pronoun correctly referring to the patients.
"They" is subjective, "them" is objective, and "there" indicates a place.
9 Which of the following is an example of active transport across a cell
membrane?
A. Diffusion of oxygen
B. Facilitated diffusion of glucose
C. The sodium-potassium pump
D. Osmosis of water
Answer: C
Rationale: The sodium-potassium pump uses ATP to move ions against their
concentration gradient, which defines active transport. The other options are
passive transport.
10 A patient has an order for heparin 8,000 units subcutaneously. The vial reads
10,000 units/mL. How many mL will you draw?
A. 0.8 mL
B. 1.0 mL
C. 1.2 mL
D. 0.6 mL
Answer: A
, Rationale: 8,000 units ÷ 10,000 units/mL = 0.8 mL. This is a straightforward ratio
and proportion calculation.
11 When transferring a patient from bed to stretcher using a draw sheet, what
action best protects the nurse's back?
A. Bending at the waist and pulling
B. Keeping the feet together and twisting
C. Bending at the knees and keeping the back straight
D. Reaching over the patient as far as possible
Answer: C
Rationale: Bending at the knees and keeping the back straight uses leg muscles and
maintains proper body mechanics, reducing the risk of back injury.
12 Read the passage: "The nurse observed that the wound was erythematous, with
moderate serosanguineous drainage. The edges were approximated, and there was
no foul odor." What does "erythematous" mean?
A. Swollen
B. Reddened
C. Warm
D. Painful
Answer: B
Rationale: Erythematous means redness of the skin or tissue, often indicating
inflammation or infection. The other options describe other signs.
13 A medication is available as 50 mg/2 mL. How many mL are needed for a 75
mg dose?
A. 2.5 mL
B. 3.0 mL
C. 3.5 mL
D. 4.0 mL
Answer: B
Rationale: Set up proportion: 50 mg/2 mL = 75 mg/x mL. Cross-multiply: 50x =
150, x = 3.0 mL.
14 Which sentence is grammatically correct?
A. The patient did not respond to the medication, which concerned the nurse.
B. The patient did not respond to the medication which concerned the nurse.
C. The patient did not respond to the medication, that concerned the nurse.
D. The patient did not respond to the medication that concerned the nurse.
Answer: A
