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NR 566 FINAL EXAM TEST BANK 500+
QUESTIONS AND CORRECT VERIFED
ANSWERS |RATED A+ | HIGHLY
RECOMMENDED BY EXPERTS |INSTANT
DOWNLOAD PDF
Diphenhydramine (Benadryl) and Doxylamine (Unisom) - ANSWER-
Two most common H1 antagonist sleep aids
What are H1 antagonists used to treat in allergic disorders? - ANSWER-
Mild allergic reactions, such as allergic rhinitis and urticaria.
What are the anticholinergic adverse effects of H1 antagonists? -
ANSWER- Dry mouth and urinary retention
What depressive effects can H1 antagonists cause? - ANSWER-
Sedation and impaired ability, more common in FGA due to crossing the
BBB
What behavioral adverse effects are associated with H1 antagonists? -
ANSWER- Confusion and apathy
What stimulatory effects can H1 antagonists have? - ANSWER- Muscle
spasm and appetite stimulation
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What gastrointestinal adverse effects can occur with H1 antagonists? -
ANSWER- Discomfort
What can happen at high doses of H1 antagonists? - ANSWER- CNS
seizures and hallucinations
In which populations are H1 antagonists contraindicated? - ANSWER-
Newborns, children under the age of 2, and women who are
breastfeeding.
What conditions contraindicate the use of H1 antagonists? - ANSWER-
Narrow-angle glaucoma, prostatic hypertrophy, and acute exacerbation
of asthma.
What is the effect of H1 antagonists on allergic rhinitis? - ANSWER-
Reduces sneezing, nasal discharge, and irritation of the eyes, nose, and
throat.
What is the mechanism of action (MOA) of H1 antagonists? -
ANSWER- H1 antagonists work by blocking H1 histamine receptors.
What effect do H1 antagonists have on histamine in the body? -
ANSWER- They help to reduce the effects of histamine in the body.
How does blocking histamine action affect wakefulness? - ANSWER-
Blocking histamine action can lead to sedation and help induce sleep.
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What is a common side effect of H1 antagonists when used as a sleep
aid? - ANSWER- Daytime Drowsiness: Users may experience lingering
sedation the next day.
What are some anticholinergic effects of H1 antagonists? - ANSWER-
Dry mouth, blurred vision, constipation, and urinary retention.
What CNS effects can H1 antagonists cause, particularly in older adults?
- ANSWER- Dizziness, confusion, and incoordination.
What is the effect of H1 antagonists on urticaria? - ANSWER-
Diminishes redness, itching, and swelling.
Which first-generation H1 antagonists are effective for motion sickness?
- ANSWER- Promethazine and dimenhydrinate.
How do certain H1 antagonists help with motion sickness? - ANSWER-
They inhibit muscarinic receptors.
Why are first-generation H1 antagonists included in sleep aids? -
ANSWER- For short-term management of sleep disturbances.
What are the anticholinergic effects that older adults are more
susceptible to? - ANSWER- Dizziness, confusion, and sedation.
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Why should first-generation antihistamines be used cautiously in older
adults? - ANSWER- They can increase sedation and anticholinergic
effects, raising the risk of falls and accidents.
What criteria advises against the use of first-generation antihistamines in
older adults? - ANSWER- Beers Criteria.
What is a concern regarding polypharmacy in older adults? - ANSWER-
Increased risk of drug interactions and cumulative side effects.
What effect can first-generation antihistamines have on children? -
ANSWER- They can cause paradoxical excitation, leading to increased
agitation or insomnia.
What is advised for the use of antihistamines in infants? - ANSWER-
Over-the-counter cold remedies should generally be avoided in children
under four years old.
What is the Pregnancy Risk Category for antihistamines? - ANSWER-
Category C, meaning they should only be used if benefits outweigh
risks.
Which type of antihistamines are often preferred during pregnancy? -
ANSWER- Second-generation antihistamines due to a better safety
profile.
4|Page
NR 566 FINAL EXAM TEST BANK 500+
QUESTIONS AND CORRECT VERIFED
ANSWERS |RATED A+ | HIGHLY
RECOMMENDED BY EXPERTS |INSTANT
DOWNLOAD PDF
Diphenhydramine (Benadryl) and Doxylamine (Unisom) - ANSWER-
Two most common H1 antagonist sleep aids
What are H1 antagonists used to treat in allergic disorders? - ANSWER-
Mild allergic reactions, such as allergic rhinitis and urticaria.
What are the anticholinergic adverse effects of H1 antagonists? -
ANSWER- Dry mouth and urinary retention
What depressive effects can H1 antagonists cause? - ANSWER-
Sedation and impaired ability, more common in FGA due to crossing the
BBB
What behavioral adverse effects are associated with H1 antagonists? -
ANSWER- Confusion and apathy
What stimulatory effects can H1 antagonists have? - ANSWER- Muscle
spasm and appetite stimulation
1|Page
,2|Page
What gastrointestinal adverse effects can occur with H1 antagonists? -
ANSWER- Discomfort
What can happen at high doses of H1 antagonists? - ANSWER- CNS
seizures and hallucinations
In which populations are H1 antagonists contraindicated? - ANSWER-
Newborns, children under the age of 2, and women who are
breastfeeding.
What conditions contraindicate the use of H1 antagonists? - ANSWER-
Narrow-angle glaucoma, prostatic hypertrophy, and acute exacerbation
of asthma.
What is the effect of H1 antagonists on allergic rhinitis? - ANSWER-
Reduces sneezing, nasal discharge, and irritation of the eyes, nose, and
throat.
What is the mechanism of action (MOA) of H1 antagonists? -
ANSWER- H1 antagonists work by blocking H1 histamine receptors.
What effect do H1 antagonists have on histamine in the body? -
ANSWER- They help to reduce the effects of histamine in the body.
How does blocking histamine action affect wakefulness? - ANSWER-
Blocking histamine action can lead to sedation and help induce sleep.
2|Page
,3|Page
What is a common side effect of H1 antagonists when used as a sleep
aid? - ANSWER- Daytime Drowsiness: Users may experience lingering
sedation the next day.
What are some anticholinergic effects of H1 antagonists? - ANSWER-
Dry mouth, blurred vision, constipation, and urinary retention.
What CNS effects can H1 antagonists cause, particularly in older adults?
- ANSWER- Dizziness, confusion, and incoordination.
What is the effect of H1 antagonists on urticaria? - ANSWER-
Diminishes redness, itching, and swelling.
Which first-generation H1 antagonists are effective for motion sickness?
- ANSWER- Promethazine and dimenhydrinate.
How do certain H1 antagonists help with motion sickness? - ANSWER-
They inhibit muscarinic receptors.
Why are first-generation H1 antagonists included in sleep aids? -
ANSWER- For short-term management of sleep disturbances.
What are the anticholinergic effects that older adults are more
susceptible to? - ANSWER- Dizziness, confusion, and sedation.
3|Page
, 4|Page
Why should first-generation antihistamines be used cautiously in older
adults? - ANSWER- They can increase sedation and anticholinergic
effects, raising the risk of falls and accidents.
What criteria advises against the use of first-generation antihistamines in
older adults? - ANSWER- Beers Criteria.
What is a concern regarding polypharmacy in older adults? - ANSWER-
Increased risk of drug interactions and cumulative side effects.
What effect can first-generation antihistamines have on children? -
ANSWER- They can cause paradoxical excitation, leading to increased
agitation or insomnia.
What is advised for the use of antihistamines in infants? - ANSWER-
Over-the-counter cold remedies should generally be avoided in children
under four years old.
What is the Pregnancy Risk Category for antihistamines? - ANSWER-
Category C, meaning they should only be used if benefits outweigh
risks.
Which type of antihistamines are often preferred during pregnancy? -
ANSWER- Second-generation antihistamines due to a better safety
profile.
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