Test Bank For Advanced Physiology and
Pathophysiology, 2nd Edition, By Nancy Tkacs,
All Chapters 1-17 LATEST
MCV - Correct Answer>>>mean cell volume- hematocrit divided #
RBCs, normally 80-100 fL
RDW - Correct Answer>>>red cell distribution width- variability in red
blood cell sizes, abnormally high variability is called anisocytosis
Macrocytosis - Correct Answer>>>>100 fL sized RBC
Microcytosis - Correct Answer>>><80 fL sized RBC
Erythropoietin - Correct Answer>>>glycoprotein thats made and
secreted by kidneys and circulates to bone marrow to stimulate RBC
production
Reticulocyte - Correct Answer>>>immature erythrocyte, it does not
have a nucleus, its leaving the bone marrow and entering circulation
where it will eventually lose the organelles and become mature
erythrocyte
What organelles are found in mature RBC - Correct Answer>>>no
nuclei no organelles. reticulocytes (immature) do have the ribosomes
and RNA which gets dropped once circulating and maturing to
erythrocyte
, What protein does RBCs synthesize - Correct Answer>>>NONE TRICK
QUESTION HOE - a bih don't even have organelles
Hemoglobin (HbA) - Correct Answer>>>Adult hemoglobin- 2 pairs
globins alpha and beta, 4 heme/iron complexes.
Hemoglobin (HbF) - Correct Answer>>>Fetal hemoglobin - 2 pairs alpha
and gamma globins. at 38 weeks gestation babies start to switch to
adult Hemoglobin
Sickle Cell - Correct Answer>>>single gene (missense mutation)
recessive disorder, mutation in Beta global gene, 6th amino acid
glutamate is substituted for Valic acid and causes protein folding to
have changed shape (new hydrophobic region). Beta chain of
hemoglobin S, leads to elongated sickle shape
Thalassemia - Correct Answer>>>term for genetic disorders that result
in abnormal production of either Alpha or Beta hemoglobin chains.
(sickle cell is a type of thalassemia) - RBC function impacted by
decrease in correct globin production but also build up of abnormal
levels of unaffected global chains leads to hemolysis
How is iron transported in the blood? - Correct Answer>>>transferrin
carries iron in blood to the red bone marrow to erythroblasts
Pathophysiology, 2nd Edition, By Nancy Tkacs,
All Chapters 1-17 LATEST
MCV - Correct Answer>>>mean cell volume- hematocrit divided #
RBCs, normally 80-100 fL
RDW - Correct Answer>>>red cell distribution width- variability in red
blood cell sizes, abnormally high variability is called anisocytosis
Macrocytosis - Correct Answer>>>>100 fL sized RBC
Microcytosis - Correct Answer>>><80 fL sized RBC
Erythropoietin - Correct Answer>>>glycoprotein thats made and
secreted by kidneys and circulates to bone marrow to stimulate RBC
production
Reticulocyte - Correct Answer>>>immature erythrocyte, it does not
have a nucleus, its leaving the bone marrow and entering circulation
where it will eventually lose the organelles and become mature
erythrocyte
What organelles are found in mature RBC - Correct Answer>>>no
nuclei no organelles. reticulocytes (immature) do have the ribosomes
and RNA which gets dropped once circulating and maturing to
erythrocyte
, What protein does RBCs synthesize - Correct Answer>>>NONE TRICK
QUESTION HOE - a bih don't even have organelles
Hemoglobin (HbA) - Correct Answer>>>Adult hemoglobin- 2 pairs
globins alpha and beta, 4 heme/iron complexes.
Hemoglobin (HbF) - Correct Answer>>>Fetal hemoglobin - 2 pairs alpha
and gamma globins. at 38 weeks gestation babies start to switch to
adult Hemoglobin
Sickle Cell - Correct Answer>>>single gene (missense mutation)
recessive disorder, mutation in Beta global gene, 6th amino acid
glutamate is substituted for Valic acid and causes protein folding to
have changed shape (new hydrophobic region). Beta chain of
hemoglobin S, leads to elongated sickle shape
Thalassemia - Correct Answer>>>term for genetic disorders that result
in abnormal production of either Alpha or Beta hemoglobin chains.
(sickle cell is a type of thalassemia) - RBC function impacted by
decrease in correct globin production but also build up of abnormal
levels of unaffected global chains leads to hemolysis
How is iron transported in the blood? - Correct Answer>>>transferrin
carries iron in blood to the red bone marrow to erythroblasts
