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NR566 MIDTERM EXAM REVIEW
2026/2027 ACTUAL QUESTIONS
WITH VERIFIED ANSWERS.
Which non-amphetamines are FDA approved for weight loss
that have lower abuse risk? - ANSWER-Phentermine and
Diethylpropion
How does Phentermine and Diethylpropion promote weight
loss? - ANSWER--Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that
suppress appetite by increasing the availability of
norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-
amphetamines? - ANSWER-3 months or less
What drug schedule are Phentermine and Diethylpropion
under? - ANSWER-Schedule IV
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What labs should be monitored with Phentermine and
Diethylpropion? What condition should we screen for? -
ANSWER--baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - ANSWER--increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - ANSWER-Increases
satiety
What are some Phentermine/topiramate contraindications for
use? - ANSWER-not approved in children and contraindicated
with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate
to avoid insomnia? - ANSWER-given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? - ANSWER-hx drug
abuse, glaucoma, pregnant, HTN, hyperthyroidism
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Phentermine/topiramate adverse effects - ANSWER-insomnia,
nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to
prescribing phentermine/topiramate? Select all that apply. -
ANSWER-A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and
reduces absorption of fat by 30%. - ANSWER-GI tract
Take multivitamin ___hours before/after to supplement fat-
soluble vitamins that may not be absorbed well when taking
Orlistat. - ANSWER-2
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Orlistat is OTC as 60 mg TID with meals. Not approved in
children <____. - ANSWER-12
Orlistat results in the least amount of weight loss of all. How
much? - ANSWER-2-3% body weight (7 lbs in year)
Orlistat adverse effects - ANSWER-Fecal incontinence, oily
rectal leakage, flatus, abdominal cramps. liver damage (light-
colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - ANSWER-In those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking
Orlistat...especially if the patient is on coumadin? - ANSWER-
Monitor Coumadin as Vitamin K deficiency may occur and
intensify effect of Coumadin.
NR566 MIDTERM EXAM REVIEW
2026/2027 ACTUAL QUESTIONS
WITH VERIFIED ANSWERS.
Which non-amphetamines are FDA approved for weight loss
that have lower abuse risk? - ANSWER-Phentermine and
Diethylpropion
How does Phentermine and Diethylpropion promote weight
loss? - ANSWER--Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that
suppress appetite by increasing the availability of
norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-
amphetamines? - ANSWER-3 months or less
What drug schedule are Phentermine and Diethylpropion
under? - ANSWER-Schedule IV
,2 | Page
What labs should be monitored with Phentermine and
Diethylpropion? What condition should we screen for? -
ANSWER--baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects - ANSWER--increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss? - ANSWER-Increases
satiety
What are some Phentermine/topiramate contraindications for
use? - ANSWER-not approved in children and contraindicated
with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate
to avoid insomnia? - ANSWER-given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution? - ANSWER-hx drug
abuse, glaucoma, pregnant, HTN, hyperthyroidism
,3 | Page
Phentermine/topiramate adverse effects - ANSWER-insomnia,
nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to
prescribing phentermine/topiramate? Select all that apply. -
ANSWER-A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and
reduces absorption of fat by 30%. - ANSWER-GI tract
Take multivitamin ___hours before/after to supplement fat-
soluble vitamins that may not be absorbed well when taking
Orlistat. - ANSWER-2
, 4 | Page
Orlistat is OTC as 60 mg TID with meals. Not approved in
children <____. - ANSWER-12
Orlistat results in the least amount of weight loss of all. How
much? - ANSWER-2-3% body weight (7 lbs in year)
Orlistat adverse effects - ANSWER-Fecal incontinence, oily
rectal leakage, flatus, abdominal cramps. liver damage (light-
colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated? - ANSWER-In those with
malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking
Orlistat...especially if the patient is on coumadin? - ANSWER-
Monitor Coumadin as Vitamin K deficiency may occur and
intensify effect of Coumadin.
