APSC 4464 Exam 2 Questions and Correct
Answers
inactivated vaccines
less immunogenic, highly stable, post-vaccinial reactions, multiple dose vials; given SQ or IM
attenuated vaccines
highly immunogenic, freeze-dried state, lack of thermostability, most effective, lasts for many
years; given IN or parenterally
recombinant vaccines
stronger and faster immunity, not made from whole virus
toxoid vaccines
multiple sequential initial doses, duration not comparable to attenuated; made from selected
toxins that have been sufficiently attenuated
immunotherapeutic biologics
support the treatment of conditions (cancer); monoclonal antibodies
Maternally derived antibodies
block effectiveness of vaccines if dog is under 12 weeks
Window of susceptibility
maternal ABs are too low to provide protection but too high for vaccines to work
transient postvaccinal nonspecific illness
,regional lymphadenomegaly, encephalitis, hair loss, color change
multisystemic infectious disorder of young weimaraner dogs
genetically linked to both immunodeficiency/autoimmune disorder that are detected shortly after
vaccination
vaccine-induced immunosuppression
associated with 1st or 2nd dose of combination MLV; increased susceptibility to other diseases
core canine vaccines
rabies, distemper, parvo, adenovirus-2, parainfluenza, leptospirosis
core feline vaccines
FPV, FHV1, FCV, FeLV, rabies, infectious peritonitis
TNR vaccines
FPV, FHV1, FCV, rabies
shelter dog vaccines
CDV, CPV2, CAV-2, IN Bb+CPiV, RV
inactivated vaccine example
canine influenza, some feline leukemia
attenuated vaccine example
parvo, feline panleukopenia virus
recombinant vaccine example
, canine distemper, feline rabies
feline injection-site sarcoma
vaccine associated sarcoma; development at sites inactivated rabies or FeLV vaccines and
aluminum-based adjuvants; very low current risk
Feline Panleukopenia Virus (FPV)
feline distemper; contagious and often fatal; affects and destroys actively dividing cells, bone
marrow, lymphoid cells, intestinal epithelium; cerebellar hypoplasia in kittens
feline leukemia (FeLV)
most common cause of cancer in cats; spread from mother to kitten; spread in saliva;
oncogenesis when inserts into host cellular genome
bordetella Bronchiseptica
highly contagious respiratory disease; most severe in kittens
chlamydophilia Felis
URI; conjunctivitis; direct contact; edema of conjunctiva
feline infectious peritonitis
immune-mediated disease triggered by infection with a feline coronavirus; polygenic trait
heritability; clinical signs depending on organ development (liver, kidneys, pancreas, CNS, eyes)
wet effusive form FIP
Answers
inactivated vaccines
less immunogenic, highly stable, post-vaccinial reactions, multiple dose vials; given SQ or IM
attenuated vaccines
highly immunogenic, freeze-dried state, lack of thermostability, most effective, lasts for many
years; given IN or parenterally
recombinant vaccines
stronger and faster immunity, not made from whole virus
toxoid vaccines
multiple sequential initial doses, duration not comparable to attenuated; made from selected
toxins that have been sufficiently attenuated
immunotherapeutic biologics
support the treatment of conditions (cancer); monoclonal antibodies
Maternally derived antibodies
block effectiveness of vaccines if dog is under 12 weeks
Window of susceptibility
maternal ABs are too low to provide protection but too high for vaccines to work
transient postvaccinal nonspecific illness
,regional lymphadenomegaly, encephalitis, hair loss, color change
multisystemic infectious disorder of young weimaraner dogs
genetically linked to both immunodeficiency/autoimmune disorder that are detected shortly after
vaccination
vaccine-induced immunosuppression
associated with 1st or 2nd dose of combination MLV; increased susceptibility to other diseases
core canine vaccines
rabies, distemper, parvo, adenovirus-2, parainfluenza, leptospirosis
core feline vaccines
FPV, FHV1, FCV, FeLV, rabies, infectious peritonitis
TNR vaccines
FPV, FHV1, FCV, rabies
shelter dog vaccines
CDV, CPV2, CAV-2, IN Bb+CPiV, RV
inactivated vaccine example
canine influenza, some feline leukemia
attenuated vaccine example
parvo, feline panleukopenia virus
recombinant vaccine example
, canine distemper, feline rabies
feline injection-site sarcoma
vaccine associated sarcoma; development at sites inactivated rabies or FeLV vaccines and
aluminum-based adjuvants; very low current risk
Feline Panleukopenia Virus (FPV)
feline distemper; contagious and often fatal; affects and destroys actively dividing cells, bone
marrow, lymphoid cells, intestinal epithelium; cerebellar hypoplasia in kittens
feline leukemia (FeLV)
most common cause of cancer in cats; spread from mother to kitten; spread in saliva;
oncogenesis when inserts into host cellular genome
bordetella Bronchiseptica
highly contagious respiratory disease; most severe in kittens
chlamydophilia Felis
URI; conjunctivitis; direct contact; edema of conjunctiva
feline infectious peritonitis
immune-mediated disease triggered by infection with a feline coronavirus; polygenic trait
heritability; clinical signs depending on organ development (liver, kidneys, pancreas, CNS, eyes)
wet effusive form FIP
