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Localized egophony - DETAILED ANSWER-Most likely implies lung consolidation, such as pneumonia.
Percussion of the thorax - DETAILED ANSWER-Helps identify if underlying tissues are air-filled,
fluidfilled, or consolidated.
Forced Vital Capacity (FVC) - DETAILED ANSWER-Expected to be less-than-expected in patients with
severe interstitial lung disease.
Forced Expiratory Volume in 1 second (FEV₁) - DETAILED ANSWER-A decreased level is most
suggestive of obstructive lung disease.
Graves' Disease - DETAILED ANSWER-Most likely diagnosis for a patient with goiter and symptoms
of anxiety, palpitations, and tremor.
Exophthalmos - DETAILED ANSWER-A typical sign associated with Graves' hyperthyroidism.
Cushing's disease findings - DETAILED ANSWER-Common findings include moon facies, abdominal
striae, and central obesity; low body temperature is not typical.
,Diabetes Mellitus Type 2 evaluation - DETAILED ANSWER-Should include annual renal function tests,
urinalysis, and a dilated eye exam.
Model for End-Stage Liver Disease (MELD) Score - DETAILED ANSWER-The MELD score is specifically
used to prioritize and assess transplant need in cirrhosis.
Deep palpitation - DETAILED ANSWER-An enlarged spleen is at risk of rupture, so avoid deep
palpation if mononucleosis is suspected.
Gram negative rods - DETAILED ANSWER-Perforated ulcers and resultant peritonitis often involve
gram-negative enteric organisms (e.g., E. coli).
Hydrocele - DETAILED ANSWER-A fluid-filled scrotal enlargement that can transilluminate is most
consistent with a hydrocele.
Leaning forward - DETAILED ANSWER-Sinus pressure typically worsens when bending or leaning
forward.
Lymphoma - DETAILED ANSWER-'B symptoms' (night sweats, weight loss) plus hilar
lymphadenopathy strongly suggests lymphoma.
Ehlers-Danlos - DETAILED ANSWER-Ehlers-Danlos syndrome, a connective tissue disorder, can be
linked to vitreous abnormalities.
Homonymous hemianopia - DETAILED ANSWER-Loss of the right visual field in both eyes is a right
homonymous hemianopia (post-chiasmal lesion).
S1 heart sound - DETAILED ANSWER-Auscultated during systole, marking the closure of the mitral
and tricuspid valves.
,Basic metabolic profile - DETAILED ANSWER-The initial test for a patient with new palpitations,
including electrolytes and an ECG.
Aortic valve location - DETAILED ANSWER-Best identified at the 2nd intercostal space, right sternal
border.
Dual antiplatelet therapy (DAPT) duration - DETAILED ANSWER-Recommended for at least 12
months after drug-eluting stent placement in cases of elevated troponin.
TIBC and ferritin - DETAILED ANSWER-Iron studies (especially serum ferritin, TIBC) confirm iron
deficiency (the most common cause of microcytosis with high RDW).
Thalassemia trait - DETAILED ANSWER-Thalassemia typically shows microcytosis with normal RBC
distribution width, as opposed to iron deficiency (which raises RDW).
Vitamin B12 - DETAILED ANSWER-Macrocytosis suggests checking B12 or folate to differentiate
causes.
Normal MCH, hemoglobin 9.6 - DETAILED ANSWER-ESRD often causes a normocytic, normochromic
anemia (low hemoglobin, but normal indices).
Aspirin use - DETAILED ANSWER-Reye syndrome in children has been associated with aspirin
administration during viral illnesses.
IgM - DETAILED ANSWER-IgM anti-HAV rises early in acute hepatitis A infections.
, Hepatitis Core antibody - DETAILED ANSWER-After about a year, the IgG core antibody (anti-HBc)
typically remains positive in ongoing or past HBV infection.
Antinuclear antibody - DETAILED ANSWER-ANA testing is the primary screening test for SLE.
Apocrine - DETAILED ANSWER-Apocrine sweat gland obstruction (e.g., in hidradenitis suppurativa)
often leads to abscess formation.
Irregular border - DETAILED ANSWER-An irregular or poorly demarcated border is a classic red flag
for melanoma.
Actinic keratosis - DETAILED ANSWER-Actinic (solar) keratoses are considered premalignant lesions
from sun (UV-B) damage.
Diameter of 0.8 cm - DETAILED ANSWER-Lesions >6 mm (0.6 cm) in diameter are concerning ("D" in
ABCDE). At 0.8 cm, it's suspicious.
GABA - DETAILED ANSWER-Alcohol enhances GABA; withdrawal states lead to relative GABA
deficiency, causing hyperadrenergic symptoms.
TSH and free T4 - DETAILED ANSWER-Thyroid function tests help rule out hyperthyroidism, which
can mimic anxiety symptoms.
Olfactory - DETAILED ANSWER-Perceiving nonexistent odors is an olfactory hallucination.
Depression - DETAILED ANSWER-Depression is the most frequent psychiatric condition co-existing
with self-harm/suicidality.