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ABSITE EXAM MASTERY: 750 ACTUAL QUESTIONS WITH CORRECT ANSWERS & DETAILED RATIONALES FOR SURGICAL RESIDENCY SUCCESS

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Ace Your ABSITE Exam with This Comprehensive Q-Bank! This 167-page PDF contains 750 expertly-crafted practice questions mirroring the ACTUAL ABSITE Examination—covering the ENTIRE surgical curriculum from critical care (SICU, shock, ARDS, sepsis) and trauma (penetrating/ blunt injuries, hemorrhagic shock, vascular injury) to gastrointestinal surgery (appendicitis, pancreatitis, cholecystitis, IBD), vascular surgery (AAA, PAD, carotid disease, endoleaks), endocrine surgery (thyroid, parathyroid, adrenal, breast), pediatric surgery (pyloric stenosis, intussusception, Hirschsprung's, NEC), transplantation (immunosuppression, rejection, CMV), burns (Parkland formula, escharotomy, wound sepsis), and surgical ethics/ professionalism! Each question includes the correct answer AND a detailed, exam-style rationale explaining the pathophysiology, surgical management, and clinical decision-making behind it—so you understand the "why" not just memorize answers. Perfect for general surgery residents, medical students, and surgical trainees preparing for ABSITE, board exams, or in-service training exams. Topics include: ventilator management, acid-base disorders, vasopressor selection, massive transfusion protocols, qSOFA criteria, traumatic brain injury (ICP/CPP), penetrating neck/chest/abdominal trauma, damage control surgery, acute limb ischemia, AAA rupture/repair, EVAR complications, pancreatic adenocarcinoma, GI bleeding management, inflammatory bowel disease surgical options, breast cancer (ER/PR/HER2), melanoma staging (SLNB), thyroid nodule management (Bethesda categories), pheochromocytoma workup, pediatric surgical emergencies, burn resuscitation formulas, and ethical scenarios (living wills, informed consent, impaired colleagues). Stop guessing—start mastering surgical principles! Save hundreds of study hours with questions designed to build clinical reasoning and boost ABSITE percentile scores. BONUS: Covers high-yield topics like damage control resuscitation, ATLS principles, SCCM sepsis guidelines, and ACS NSQIP benchmarks—exactly what ABSITE examiners expect you to know!

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Institution
ABSITE
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ABSITE

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ABSITE EXAM 2 NEWEST 2026/ 2027 TEST BANK|

COMPLETE 750 ACTUAL EXAM QUESTIONS AND

CORRECT DETAILED ANSWERS (VERIFIED ANSWERS)

ALREADY GRADED A+| ABSITE EXAM PREP (BRAND

NEW!!)

Question 1

A 55-year-old man in the SICU with septic shock has a central

venous oxygen saturation (ScvO2) of 55% after initial fluid

resuscitation of 30 mL/kg. His hemoglobin is 8.5 g/dL, and mean

arterial pressure (MAP) is 65 mmHg on norepinephrine. What is

the most appropriate next step?

A. Transfuse packed red blood cells to goal hemoglobin >10

g/dL

B. Start dobutamine

C. Increase norepinephrine dose



1

,D. Administer hydrocortisone

E. Repeat fluid bolus

Answer: B

*Rationale: Persistent low ScvO2 (<70%) after adequate fluids

and MAP indicates inadequate oxygen delivery. Dobutamine

increases cardiac output. Transfusion is indicated if Hgb <7 g/dL

(or <8 with cardiac disease).*




Question 2

A patient is intubated with the following ABG: pH 7.21, PaCO2

60 mmHg, PaO2 85 mmHg, HCO3 24 mEq/L on FiO2 0.5. The

ventilator rate is 12 breaths/min. What is the most appropriate

change?

A. Increase FiO2 to 0.6

B. Increase rate to 18 breaths/min

C. Increase tidal volume from 450 mL to 550 mL

2

,D. Add PEEP of 10 cm H2O

E. Change to pressure control ventilation

Answer: B

Rationale: Acute respiratory acidosis (pH <7.30, PaCO2 >45,

normal HCO3) requires increased minute ventilation. Increasing

rate is safer than increasing tidal volume (barotrauma risk).




Question 3

Which of the following is a contraindication to therapeutic

hypothermia after cardiac arrest?

A. Time to ROSC of 40 minutes

B. Initial rhythm of ventricular fibrillation

C. Pregnancy

D. Age >75 years

E. Pre-arrest GCS of 14



3

, Answer: C

Rationale: Pregnancy, active bleeding, severe sepsis, and

prolonged downtime >60 minutes are contraindications. VF arrest

has best outcomes with hypothermia.




Question 4

A 28-year-old man with multiple gunshot wounds receives 15

units of packed red blood cells, 10 units of platelets, and 8 units

of plasma over 6 hours. He now has oozing from his IV sites and

chest tube. Laboratory studies show: PT 18 seconds (normal 12),

PTT 45 seconds (normal 25), fibrinogen 90 mg/dL, platelets

80,000/μL. What is the most appropriate next step?

A. Give additional 2 units of platelets

B. Give cryoprecipitate

C. Give vitamin K



4

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Number of pages
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