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Immunology Flashcards _ Quizlet.pdf

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Immunology Flashcards _ Q

Institution
Clinical Chemistry
Course
Clinical chemistry

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Science Biology Immunology


Immunology
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Terms in this set (157) Hide definitions




Most common immunoglobin found in Multiple Myeloma IgG
patients:


Autoantibody indicative of Graves Disease Thyroid simulating hormone receptor antibodies TRabs, some antithyroid
peroxidase


Autoantibodies seen in Hashimotos thyroiditis Antithyroid peroxidase




Autoantibodie associated with Celiac Antitransglutaminase


Autoanitbody associated with Type I Diabetes Islet cell


Brutons Agamaglobulenmia is what kind of disorder? Congenital B cell disorder


Highly specific and most sensitive for RA Cyclic Citrolinnated peptide assay

, Process of monoclonal antibody production Fusion of antibody specific lymphocyte and myeloma cell


Order of EBV response in IM 1. VCA: viral capsid antigen
2. EBNA: epstein bar nuclear antigen
3. VCA/IgM: viral capsal antibody
4. EA: early antigen


Organisms best viewed under dark field microscopy Borrelia, and Treponema


PCR technique used to detect Mycobacterium TB Transcription mediated amplification


CD4 is expressed in? T-helper cells




CD3 is expressed in? All Mature T-cells (helper + suppressor)


CDRL and RPR is used to provide presumptive Detects treponema pallidum. Causative agent of Syphyllius
identification for?


Cytokines soluble proteins that regulate innate and adaptive immune responses to an
antigen.


Antibodies proteins produced by B lymphocytes that specifically react with an antigen


Properties of an antibody class are defined by the? Fc end of the molecule (portion of antibodies where the C terminal region of
each glycoprotein chain is located)
ex: activating the complement pathway, binding to NK cells


immune complex noncovalent combination of an antigen with its specific antibody


Fab region antigen combining sites that influence reactivity


Antibody most frequently present in SLE patients is Nuclear antigen
directed against?


Classical pathway Activates complement bu immune (antigen-antibody) complexes requiring IgM, or
2 IgG molecules

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