Science Medicine Hematology
Coagulation
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Anticoagulant drugs that are direct thrombin inhibitors PT, aPTT, Escarin clotting time
(ex: argatroban & bivalirudin) can prolong what clot-
based assays?
Escarin Clotting time a laboratory test that measures how long it takes for blood to clot after the
addition of a protein called ecarin. Ecarin, derived from the venom of the saw-
scaled viper, activates a protein called prothrombin to form meizothrombin, which
then leads to clotting. -used to monitor the effects of direct thrombin inhibitors
(DTIs)
In patients who developed heparin-induced Direct thrombin inhibitors
thrombocytopenia with thrombosis (HIT), what can/ be Ex: Argatroban * Bivalirudin (can be substituted for unfractionated heparin in
used to prevent ischemic stroke patients with HIT)
Coagulation
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Students also studied
Flashcard sets Study guides
Chemistry (ASCP MLT BOARD EXAM... Hematology Practice questions Hematology (MLS ASCP) Hemato
343 terms Teacher 65 terms 191 terms 54 terms
jennymathew Preview Asimpson_18 Preview Nnaeto6 Preview ssta
Terms in this set (7) Hide definitions
Anticoagulant drugs that are direct thrombin inhibitors PT, aPTT, Escarin clotting time
(ex: argatroban & bivalirudin) can prolong what clot-
based assays?
Escarin Clotting time a laboratory test that measures how long it takes for blood to clot after the
addition of a protein called ecarin. Ecarin, derived from the venom of the saw-
scaled viper, activates a protein called prothrombin to form meizothrombin, which
then leads to clotting. -used to monitor the effects of direct thrombin inhibitors
(DTIs)
In patients who developed heparin-induced Direct thrombin inhibitors
thrombocytopenia with thrombosis (HIT), what can/ be Ex: Argatroban * Bivalirudin (can be substituted for unfractionated heparin in
used to prevent ischemic stroke patients with HIT)