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Exam (elaborations)

Exam (elaborations) NR 507 ADVANCED PATHOPHYSIOLOGY

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This comprehensive, well-organized, and exam-focused resource presents clear explanations of key concepts in a structured and easy-to-follow format. It supports effective revision, strengthens understanding, reinforces essential knowledge, and helps learners prepare confidently for assessments through accurate, practical, and reliable content.

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NR 507 midterm LATEST ACTUAL EXAM WITH QUESTIONS AND CORRECT VERIFIED
ANSWERS|GRADED A+|GUARANTEED 100% PASS




Hypersensitivity: Type 1 -CORRECT ANSWER--Mediated IgE

-inflammation due to mast cell degranultion

-anaphylactic, asthma, hay fever

treatment: epinephrine



Hypersensitivity: Type 2 -CORRECT ANSWER--Cytotoxic reaction: tissue specific

-binds to the antigen ON THE CELL SURFACE

-macrophages are primary effectors cells involved

cause tissue damage or alter function



Hypersensitivity 2 -CORRECT ANSWER--Graves Disease (hyperthyroidism) -alters function not
destroy

-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis

-drug allergies

-hemolytic anemia



Hypersensitivity: type 3 -CORRECT ANSWER--Not organ specific

-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the
blood or bodily fluids, and the complex is then deposited in the tissues

,Hypersensitivity: Type 3 -CORRECT ANSWER--rheumatoid arthritis

-Systemic Lupus Erythematosus (SLE)

-Raynaud's



Hives (urticaria) -CORRECT ANSWER-Hypersensitivity Type 1



First responders to innate the immune system -CORRECT ANSWER-Neutrophils



Allergic contact dermatitis -CORRECT ANSWER-Hypersensitivity Type IV



Type 2 cytotoxic hypersensitivity mediated by: -CORRECT ANSWER--IgG IgM

-macrophages are primary effort cells

-



Serum Sickness -CORRECT ANSWER-type 3 hypersensitivity



Hypersensitivity IV, -CORRECT ANSWER--is more of a delayed immune response.

-mediated T-cells attack tissue directly (no antibodies)



Autoimmune -CORRECT ANSWER--diseases in which the body makes antibodies directed
against its own tissues

-



Primary immunodeficiency -CORRECT ANSWER--Genetic; inherited

-result of single gene defects

-B and T cell deficiencies



secondary immunodeficiency -CORRECT ANSWER--acquired

, Common cause of secondary immunodeficiency -CORRECT ANSWER-Malnutrition



Most patients diagnosed with SLE will have a positive ? -CORRECT ANSWER-antinuclear
antibody (ANA)



SLE (lupus) -CORRECT ANSWER--Facial rash

-vasculitis

- tissue inflammation



Renal disease associated with autoimmunity? -CORRECT ANSWER-Glomerulonephritis



Sjogren's syndrome -CORRECT ANSWER-Inflammation in salivary and lacrimal glands



SLE -CORRECT ANSWER-Autoantibodies and auto-active t-cells against DNA and
nucleoprotein



Sjögren's syndrome immune changes: -CORRECT ANSWER-Autoantibodies and auto-reactive
t-cells against apoptotic cells



rheumatoid arthritis manifestations: -CORRECT ANSWER-Joint inflammation, stiffness, pain,
loss of range of motion



Rheumatoid Arthritis immune changes: -CORRECT ANSWER-T-cells and B cells against joint
associated antigens



MS manifestations -CORRECT ANSWER-Formation of sclerotic plaque in the brain, leads to
Muscle weakness and ataxia



MS immune changes -CORRECT ANSWER-T-cells against brain antigens

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