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1. A medical laboratory technician is performing a complete
blood count (CBC) using an automated analyzer. Which
parameter is calculated, not directly measured?
A. White blood cell count (WBC)
B. Hemoglobin (Hgb)
C. Mean corpuscular volume (MCV)
D. Red blood cell count (RBC)
Answer: C
Rationale: MCV is calculated using the formula: (Hematocrit ×
10) ÷ RBC count. WBC, Hgb, and RBC are directly measured by
automated analyzers.
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,2. A patient's blood smear shows numerous target cells
(codocytes). Which condition is most commonly associated
with this finding?
A. Iron deficiency anemia
B. Liver disease
C. Sickle cell anemia
D. Folate deficiency
Answer: B
Rationale: Target cells (codocytes) are associated with liver
disease (due to altered lipid metabolism), thalassemia, and
hemoglobin C disease. Iron deficiency typically shows
hypochromic microcytic cells.
3. A urine dipstick test is positive for blood, but no red blood
cells are seen on microscopic examination. What is the most
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,likely explanation?
A. Myoglobinuria or hemoglobinuria
B. Contamination with menstrual blood
C. Urinary tract infection
D. Kidney stones
Answer: A
Rationale: Positive blood on dipstick with no RBCs on microscopy
suggests myoglobinuria (muscle breakdown) or hemoglobinuria
(intravascular hemolysis). Dipstick detects heme, not intact RBCs.
4. Which of the following anticoagulants is most appropriate
for a prothrombin time (PT) and international normalized ratio
(INR) test?
A. EDTA (lavender top)
B. Sodium citrate (light blue top)
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, C. Heparin (green top)
D. Sodium fluoride (gray top)
Answer: B
Rationale: PT/INR requires whole blood collected in a light blue
top tube containing sodium citrate (3.2% or 3.8%). Citrate binds
calcium, preventing clotting.
5. A medical laboratory assistant is performing a
venipuncture using a butterfly needle. The patient has small,
fragile veins. Which gauge needle is most appropriate?
A. 18 gauge
B. 21 gauge
C. 23 gauge
D. 25 gauge
Answer: C
Rationale: A 23-gauge butterfly needle is appropriate for small,
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