nurr 201 2) Burns Exam questions and answers latest update Graded A+ A. Pathophysiological deviations that occur with patients experiencing burns; causes, -hypovolemic shock caused by a massive shift of fluids out of the blood vessels as a result of i
nurr 201 2) Burns Exam questions and answers latest update Graded A+ A. Pathophysiological deviations that occur with patients experiencing burns; causes, -hypovolemic shock caused by a massive shift of fluids out of the blood vessels as a result of increased capillary permeability and can begin as early as 20 minutes postburn. As the capillary walls become more permeable, water, sodium, and later plasma proteins (especially albumin) move into interstitial spaces and other surrounding tissue. The colloidal osmotic pressure decreases with progressive loss of protein from the vascular space. This results in more fluid shifting out of the vascular space into the interstitial spaces (Fig. 25-6). (Fluid accumulation in the interstitium is termed second spacing.) Fluid also moves to areas that normally have minimal to no fluid, a phenomenon termed third spacing. Examples of third spacing in burn injury are exudate and blister formation, as
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