Actual High-Yield Q&As with Rationales (Latest 2026)
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Intro Coverage
South University NSG 6998 FNP Predictor Exam or your upcoming APEA Predictor / National FNP
Board Certification (AANP/ANCC)? Don't risk your graduation or certification timeline on a stressful
exam!
This premium study resource features 100 high-yield, board-style multiple-choice questions
meticulously crafted to cover the critical clinical domains tested on the NSG 6998 predictor assessment.
Every single question comes complete with the correct answer clearly highlighted and a detailed
clinical rationale (explanation) to build your diagnostic reasoning and mastery of primary care guidelines.
🔑 Core Clinical Domains Fully Covered Inside This Guide:
Respiratory & Infectious Disease – CAP treatment guidelines, acute bronchitis versus pneumonia
differentiation, peritonsillar abscess versus Ludwig's angina, and mononucleosis management.
Endocrine & Metabolic Disorders – Euthyroid monitoring, lid lag mechanisms, Hashimoto's vs. Graves'
disease, Chvostek's and Trousseau's signs, Somogyi effect, and Metformin renal dosing contraindications.
Gastroenterology & Abdominal Pathology – Murphy's, McBurney's, and Rovsing's signs, acute
diverticulitis vs. appendicitis, pancreatitis biomarkers, H. pylori eradication triple therapy, and colonoscopy
screening intervals.
Pediatrics & Cardiovascular Screening – Developmental milestones, universal lipid screening ages,
Croup subglottic narrowing (steeple sign), pyloric stenosis diagnostics, epiglottitis safety protocols,
hypertrophic cardiomyopathy murmurs, and AAA ultrasound guidelines.
Dermatology, HEENT, & Genitourinary – ABCDE melanoma markers, paronychia, pediculosis capitis
first-line, otitis externa vs. media, uncomplicated cystitis, BV clue cells, Trichomoniasis strawberry cervix,
BPH vs. acute prostatitis examination safety, and testicular torsion emergencies.
Musculoskeletal, Neurology, & Mental Health – Gout vs. RA vs. OA nodule differentiators (Heberden's
vs. Bouchard's), Lachman's test, postmenopausal osteoporosis T-scores, acute stroke time windows,
subarachnoid thunderclap headaches, temporal arteritis emergency steroids, Parkinson's dopamine
pathways, and Anorexia Nervosa criteria.
Hematology, Pharmacology, Role, & Ethics – Iron deficiency vs. Thalassemia electrophoresis, multiple
myeloma SPEP/UPEP, sickle cell crisis hydration, LABA black-box warnings, DOAC mechanical valve
contraindications, malpractice negligence elements (Breach of Duty), and minor/adolescent confidential STI
consent rules.
Section 1: Respiratory & Infectious Disease
,1. A 76-year-old male with a history of COPD, diabetes mellitus, and chronic alcoholism
presents with productive cough and fever. His chest X-ray shows infiltrates. Which of
the following pathogens is most likely responsible for his presentation?
A) Streptococcus pneumoniae
B) Haemophilus influenzae
C) Bordetella pertussis
D) Mycoplasma pneumoniae
Rationale: While S. pneumoniae is the most common cause of community-acquired
pneumonia overall, patients with underlying chronic lung disease (COPD) and co-
morbidities like alcoholism have a significantly increased incidence of H. influenzae
infection.
2. Following the presentation of the 76-year-old male with COPD, diabetes, and
alcoholism presenting with community-acquired pneumonia, which of the following
medications is considered first-line empirical treatment?
A) Amoxicillin
B) Levofloxacin
C) Azithromycin
D) Doxycycline
Rationale: For patients with comorbidities (COPD, diabetes, alcoholism),
monotherapy with a respiratory fluoroquinolone (like Levofloxacin or Moxifloxacin) or
combination therapy with a beta-lactam plus a macrolide is required due to the risk of
drug-resistant pathogens.
3. A 32-year-old healthy non-smoker presents with a cough lasting 10 days, productive
of clear sputum, following an upper respiratory infection. He is afebrile with normal
vital signs, and his lungs are clear to auscultation. How should this patient be
managed?
, A) Treat symptoms only (supportive care)
B) Prescribe a 5-day course of Azithromycin
C) Order an immediate chest CT scan
D) Prescribe Amoxicillin-Clavulanate
Rationale: Acute bronchitis in healthy individuals is overwhelmingly viral (>90% of
cases). Treatment should focus on symptom management (antitussives, hydration)
rather than antibiotic therapy.
4. An 84-year-old male presents with a new acute productive cough, mild tachypnea,
and low-grade fever for 3 days. Which of the following diagnostic tests must the
Nurse Practitioner perform first to differentiate acute bronchitis from pneumonia?
A) Sputum culture and sensitivity
B) Chest X-ray
C) Chest CT scan
D) Peak expiratory flow measurement
Rationale: In elderly patients, atypical presentations of pneumonia are common. A
chest X-ray is warranted in patients over 65 presenting with acute cough and fever to
rule out pneumonia or consolidation.
5. A patient presents with acute onset of severe unilateral throat pain, difficulty
swallowing (dysphagia), a "hot potato" voice, and trismus. On examination, the uvula
is deviated to the opposite side. What is the most likely diagnosis?
A) Ludwig's angina
B) Peritonsillar abscess
C) Epiglottitis
D) Viral pharyngitis
Rationale: A peritonsillar abscess is characterized by unilateral swelling, uvular
, deviation away from the affected side, trismus (difficulty opening the mouth), and a
muffled voice.
6. A patient is diagnosed with Ludwig's angina. The Family Nurse Practitioner knows
that this condition primarily indicates which of the following?
A) A severe middle ear infection tracking down the neck
B) A rapidly spreading subcutaneous infection of the submandibular space
C) An autoimmune inflammation of the thyroid gland
D) A benign cystic growth on the vocal cords
Rationale: Ludwig's angina is a life-threatening, rapidly progressive cellulitis of the
submandibular, sublingual, and submental spaces, usually originating from an
infected lower molar.
7. When reviewing the clinical signs of a patient presenting with an acute cough, which
of the following clinical findings most heavily warrants ordering a chest X-ray?
A) Heart rate of 86 bpm
B) Temperature of 99.1°F
C) Rales or signs of consolidation upon auscultation
D) Clear rhinorrhea and nasal congestion
Rationale: The presence of focal rales, crackles, egophony, or tactile fremitus
suggests consolidation, which necessitates a chest X-ray to diagnose pneumonia.
8. A 19-year-old college student presents with malaise, fatigue, sore throat, and
generalized lymphadenopathy. The heterophil antibody test (Monospot) is positive,
confirming infectious mononucleosis. Which of the following is the LEAST
appropriate intervention?
A) Advise strict avoidance of contact sports for 3–4 weeks
B) Recommend rest and supportive hydration
C) Prescribe Amoxicillin for secondary bacterial prophylaxis