Maryville University Advanced Pathophysiology Exam 2
verified with correct answers 2026/2027 version
apoptosis is:- correct answer>>>normal mechanism for cells to self-destruct when
growth is excessive
many cancers create a mutation of ras. ras is a (an):- correct answer>>>intracellular-
signaling protein that regulates cell growth
oncogenes are genes that are capable of:- correct answer>>>undergoing mutation that
directs the synthesis of proteins to accelerate the rate of tissue proliferation
Burkitt lymphomas designate a chromosome that has a piece of chromosome 8 fused to
a piece of chromosome 14. This is an example of which mutation of normal genes to
oncogenes?- correct answer>>>chromosome translocation
in childhood neuroblastoma, the N-myc oncogene undergoes which type of mutation of
normal gene to oncogene?- correct answer>>>gene amplification
what aberrant change causes the abnormal growth in retinoblastoma?- correct
answer>>>the tumor suppressor gene is turned off
two "hits" are required to inactivate tumor-suppressor genes because:- correct
answer>>>each allele must be altered, and each person has two copies, or alleles of
each gene: one from each parent
the ras gene converts from a proto-oncogene to an oncogene by:- correct
answer>>>altering one or more nucleotide base pairs
how do cancer cells use the enzyme telomerase?- correct answer>>>to switch on the
telomerase to enable cells to divide indefinitely
what are characteristics of a benign tumor?- correct answer>>>they include the suffix -
oma
which terms represent the correct nomenclature for benign and malignant tumors of
adipose tissue, respectively?- correct answer>>>lipoma, liposarcoma
what is the major virus involved in the development of cervical cancer?- correct
answer>>>HPV
the papanicolaou (pap) test is used to screen for:- correct answer>>>cervical cancer
what is the skin-related health risk induced by some forms of chemotherapy?- correct
answer>>>infection
verified with correct answers 2026/2027 version
apoptosis is:- correct answer>>>normal mechanism for cells to self-destruct when
growth is excessive
many cancers create a mutation of ras. ras is a (an):- correct answer>>>intracellular-
signaling protein that regulates cell growth
oncogenes are genes that are capable of:- correct answer>>>undergoing mutation that
directs the synthesis of proteins to accelerate the rate of tissue proliferation
Burkitt lymphomas designate a chromosome that has a piece of chromosome 8 fused to
a piece of chromosome 14. This is an example of which mutation of normal genes to
oncogenes?- correct answer>>>chromosome translocation
in childhood neuroblastoma, the N-myc oncogene undergoes which type of mutation of
normal gene to oncogene?- correct answer>>>gene amplification
what aberrant change causes the abnormal growth in retinoblastoma?- correct
answer>>>the tumor suppressor gene is turned off
two "hits" are required to inactivate tumor-suppressor genes because:- correct
answer>>>each allele must be altered, and each person has two copies, or alleles of
each gene: one from each parent
the ras gene converts from a proto-oncogene to an oncogene by:- correct
answer>>>altering one or more nucleotide base pairs
how do cancer cells use the enzyme telomerase?- correct answer>>>to switch on the
telomerase to enable cells to divide indefinitely
what are characteristics of a benign tumor?- correct answer>>>they include the suffix -
oma
which terms represent the correct nomenclature for benign and malignant tumors of
adipose tissue, respectively?- correct answer>>>lipoma, liposarcoma
what is the major virus involved in the development of cervical cancer?- correct
answer>>>HPV
the papanicolaou (pap) test is used to screen for:- correct answer>>>cervical cancer
what is the skin-related health risk induced by some forms of chemotherapy?- correct
answer>>>infection