CMN 554- Unit 3 Review Test. Exam fully solved & updated (latest version
verified for accuracy) | Latest!! 554- Unit 3
What are the 3 characteristics of Asthma - (ANSWER)Bronchoconstriction
Airway Inflammation
Reversible airflow limitation
Which inhaled anticholinergic is best used for asthma pt. w/an intolerance to beta agonist or w/
bronchospasms due to beta blocker meds? - (ANSWER)Ipratropium Bromide
What is the primary tx for pt. w/moderate to severe asthma exacerbations who do not respond promptly
and completely to SABA? - (ANSWER)Systemic Corticosteroids
Which bacterial infections predispose exacerbations of asthma - (ANSWER)M. Pneumoniae and C.
Pneumoniae
Is routine use of antimicrobials recommended for acute exacerbations of asthma - (ANSWER)No, only
use when likelihood of acute bacterial respiratory tract infection
Name short acting beta agonist - (ANSWER)albuterol, levalbuterol, bitolerol, pirbuterol, terbutaline
What does a SABA do? - (ANSWER)acts directly by relaxing bronchial smooth muscles.
What do long-term pharmacologic agents accomplish for asthma pt. - (ANSWER)act primarily to
attenuate airway inflammation.
Why take long-term pharmacologic agents for asthma daily? - (ANSWER)to achieve and maintain control
of persistent asthma independent of symptoms.
What does the NAEPP recommend as the cornerstone of daily treatment of persistent asthma? -
(ANSWER)daily anti-inflammatory therapy with inhaled corticosteroids
,CMN 554- Unit 3 Review Test. Exam fully solved & updated (latest version
verified for accuracy) | Latest!! 554- Unit 3
Role of corticosteroids with asthma - (ANSWER)Reduce inflammation (acute and chronic) = improved
airflow, decreased airway hyper-responsiveness and fewer asthma exacerbations, and potentiate the
action of beta-adrenergic agonist.
1st. line treatment agent for all pt w/persistent asthma (long term controller) - (ANSWER)Inhaled
Corticosteroids
How often to most patient use inhaled corticosteroids? - (ANSWER)Twice daily to provide adequate
control.
How long can it take to see maximum response of inhaled corticosterioids? - (ANSWER)Months
What can a patient do to reduce side effects of inhaled corticosteroids? - (ANSWER)Rinse mouth after
each use
A patient has an exacerbation of asthma, what is the most effective treatment to achieve prompt
control? - (ANSWER)Systemic (oral) corticosteroids
Dose of oral corticosteroids for children during exacerbation of asthma - (ANSWER)1-2 mg/kg/day.
Can be either a single dose or divided BID.
MAX 60 mg/day
Dose of oral corticosteroids for adults during exacerbation of asthma - (ANSWER)40-60 mg/day
either as a single dose of divided BID
Duration of treatment of oral corticosteroids for asthma exacerbation - (ANSWER)3-10 days or until
symptoms resolve
(no evidence that tapering dose of PO steroids prevents relapse)
, CMN 554- Unit 3 Review Test. Exam fully solved & updated (latest version
verified for accuracy) | Latest!! 554- Unit 3
When treating exacerbation of asthma, what is the preferred treatment plan? - (ANSWER)Alternate days
rather than daily treatment.
What additional medications are required to be given concurrent with systemic corticosteroids to
prevent corticosteroid induced bone mineral loss? - (ANSWER)Vitamin D and Calcium
Should systemic corticosteroids be rapidly discontinued? - (ANSWER)No, to prevent adrenal insufficiency
Name some mediator inhibitors to treat asthma - (ANSWER)Cromolyn sodium and nedocromil
What is the mechanism of action of mediator inhibitors? - (ANSWER)prevent asthma symptoms, improve
airway function in pt w/mild persistent of exercise induce asthma
When are mediator inhibitors effective? - (ANSWER)Before allergen exposure or exercise
Do not relieve asthmatic symptoms once present.
Name the Long acting beta 2 agonist (LABA) for asthma - (ANSWER)Salmeterol and Formoteol
How are LABA's delivered? - (ANSWER)dry powder
What are LABA's used for - (ANSWER)Long term prevention of asthma symptoms
Nocturnal symptoms
Prevention of exercise induced bronchospasm
Should LABA be used as monotherapy - (ANSWER)NO
linked to fatal asthma when used alone
has no anti-inflammatory effects- so use w/a corticosteroid.
verified for accuracy) | Latest!! 554- Unit 3
What are the 3 characteristics of Asthma - (ANSWER)Bronchoconstriction
Airway Inflammation
Reversible airflow limitation
Which inhaled anticholinergic is best used for asthma pt. w/an intolerance to beta agonist or w/
bronchospasms due to beta blocker meds? - (ANSWER)Ipratropium Bromide
What is the primary tx for pt. w/moderate to severe asthma exacerbations who do not respond promptly
and completely to SABA? - (ANSWER)Systemic Corticosteroids
Which bacterial infections predispose exacerbations of asthma - (ANSWER)M. Pneumoniae and C.
Pneumoniae
Is routine use of antimicrobials recommended for acute exacerbations of asthma - (ANSWER)No, only
use when likelihood of acute bacterial respiratory tract infection
Name short acting beta agonist - (ANSWER)albuterol, levalbuterol, bitolerol, pirbuterol, terbutaline
What does a SABA do? - (ANSWER)acts directly by relaxing bronchial smooth muscles.
What do long-term pharmacologic agents accomplish for asthma pt. - (ANSWER)act primarily to
attenuate airway inflammation.
Why take long-term pharmacologic agents for asthma daily? - (ANSWER)to achieve and maintain control
of persistent asthma independent of symptoms.
What does the NAEPP recommend as the cornerstone of daily treatment of persistent asthma? -
(ANSWER)daily anti-inflammatory therapy with inhaled corticosteroids
,CMN 554- Unit 3 Review Test. Exam fully solved & updated (latest version
verified for accuracy) | Latest!! 554- Unit 3
Role of corticosteroids with asthma - (ANSWER)Reduce inflammation (acute and chronic) = improved
airflow, decreased airway hyper-responsiveness and fewer asthma exacerbations, and potentiate the
action of beta-adrenergic agonist.
1st. line treatment agent for all pt w/persistent asthma (long term controller) - (ANSWER)Inhaled
Corticosteroids
How often to most patient use inhaled corticosteroids? - (ANSWER)Twice daily to provide adequate
control.
How long can it take to see maximum response of inhaled corticosterioids? - (ANSWER)Months
What can a patient do to reduce side effects of inhaled corticosteroids? - (ANSWER)Rinse mouth after
each use
A patient has an exacerbation of asthma, what is the most effective treatment to achieve prompt
control? - (ANSWER)Systemic (oral) corticosteroids
Dose of oral corticosteroids for children during exacerbation of asthma - (ANSWER)1-2 mg/kg/day.
Can be either a single dose or divided BID.
MAX 60 mg/day
Dose of oral corticosteroids for adults during exacerbation of asthma - (ANSWER)40-60 mg/day
either as a single dose of divided BID
Duration of treatment of oral corticosteroids for asthma exacerbation - (ANSWER)3-10 days or until
symptoms resolve
(no evidence that tapering dose of PO steroids prevents relapse)
, CMN 554- Unit 3 Review Test. Exam fully solved & updated (latest version
verified for accuracy) | Latest!! 554- Unit 3
When treating exacerbation of asthma, what is the preferred treatment plan? - (ANSWER)Alternate days
rather than daily treatment.
What additional medications are required to be given concurrent with systemic corticosteroids to
prevent corticosteroid induced bone mineral loss? - (ANSWER)Vitamin D and Calcium
Should systemic corticosteroids be rapidly discontinued? - (ANSWER)No, to prevent adrenal insufficiency
Name some mediator inhibitors to treat asthma - (ANSWER)Cromolyn sodium and nedocromil
What is the mechanism of action of mediator inhibitors? - (ANSWER)prevent asthma symptoms, improve
airway function in pt w/mild persistent of exercise induce asthma
When are mediator inhibitors effective? - (ANSWER)Before allergen exposure or exercise
Do not relieve asthmatic symptoms once present.
Name the Long acting beta 2 agonist (LABA) for asthma - (ANSWER)Salmeterol and Formoteol
How are LABA's delivered? - (ANSWER)dry powder
What are LABA's used for - (ANSWER)Long term prevention of asthma symptoms
Nocturnal symptoms
Prevention of exercise induced bronchospasm
Should LABA be used as monotherapy - (ANSWER)NO
linked to fatal asthma when used alone
has no anti-inflammatory effects- so use w/a corticosteroid.
