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NURS 660 Exam 1 Antipsychotic Mastery Guide

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This comprehensive study resource features 200 expertly crafted Q&As covering all major antipsychotic medications for the NURS 660 Exam 1. Master FDA-approved indications, brand/generic names, receptor mechanisms, and unique clinical pearls for first and second-generation agents including clozapine, haloperidol, olanzapine, risperidone, aripiprazole, and novel drugs like Cobenfy. Detailed explanations highlight EPS risk profiles, metabolic effects, prolactin elevation, black box warnings, and required monitoring parameters such as ANC for clozapine and calorie requirements for lurasidone. Essential for understanding serious adverse effects including agranulocytosis, myocarditis, tardive dyskinesia, and NMS.

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NURS 660 Exam 1 LATEST UPDATE 2026/2027 200
QUESTIONS AND EXPLAINED ANSWERS |A+GRADE.
What is haloperidol (Haldol) FDA approved for? - Correct Answers - Schizophrenia, acute
psychosis, acute agitation, and Tourette syndrome.



What is lumateperone (Caplyta) FDA approved for? - Correct Answers - Schizophrenia and
bipolar depression.



What is lurasidone (Latuda) FDA approved for? - Correct Answers - Schizophrenia and
bipolar depression.



What is olanzapine (Zyprexa) FDA approved for? - Correct Answers - Schizophrenia, bipolar
disorder, and treatment-resistant depression (in combination with fluoxetine).



What is paliperidone (Invega) FDA approved for? - Correct Answers - Schizophrenia and
schizoaffective disorder.



What is paliperidone? - Correct Answers - The active metabolite of risperidone.



What is perphenazine (Trilafon) FDA approved for? - Correct Answers - Schizophrenia and
severe nausea/vomiting.



What is quetiapine (Seroquel) FDA approved for? - Correct Answers - Schizophrenia,
bipolar disorder, and adjunctive treatment of MDD.



What is Risperidone (Risperdal) FDA approved for? - Correct Answers - Schizophrenia,
bipolar mania, and irritability associated with autism.

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What is the brand name for aripiprazole? - Correct An swers - Abilify.



What is the brand name for aripiprazole? - Correct Answers - Rexulti.



What is the brand name for chlorpromazine? - Correct Answers - Thorazine.



What is the brand name for clozapine? - Correct Answers - Clozaril.



What is the brand name for Deu tetrabenazine? - Correct Answers - Austedo.



What is the brand name for haloperidol? -Correct Answers - Haldol.



What is the brand name for lumateperone? - Correct Answers - Caplyta.



What is the brand name for lurasidone? - Correct Answers - Latuda.



What is the brand name for olanzapine? - Correct Answers - Zyprexa.



What is the brand name for paliperidone? - Correct Answers - Invega.



What is the brand name for perphenazine? - Correct Answers - Trilafon.



What is the brand name for quetiapine? - Correct Answers - Seroquel.



What is the brand name for risperidone? - Correct Answers - Risperdal.

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What is the brand name for xanomeline/tropism? - Correct Answers - Cobenfy.



What is the EPS risk with quetiapine? - Correct Answers - Low.



What is the major indication for clozapine? - Correct Answers - Treatment-resistant
schizophrenia.



What is the mechanism of action of aripiprazole? - Correct Answers - D2 partial agonist
and 5HT1A partial agonist with 5HT2A antagonism.



What is the mechanism of action of aripiprazole? - Correct Answers - D2 partial agonist
and 5HT1A partial agonist with 5HT2A antagonism.



What is the mechanism of haloperidol? - Correct Answers - Potent D2 receptor
antagonism.



What is the mechanism of risperidone? - Correct Answers - D2 and 5HT2A antagonism.



What is the metabolic risk profile of lurasidone? - Correct Answers - Relatively low weight
gain and metabolic risk.



What is the unique pearl for aripiprazole? - Correct Answers - D2 partial agonist that may
lower prolactin and commonly cause akathisia.



What is the unique pearl for aripiprazole? - Correct Answers - D2 partial agonist similar to
aripiprazole but generally causes less akathisia.

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