QUESTIONS AND CORRECT
ANSWERS LATEST UPDATE
2026/2027 GRADED A+ .
,1. How do you manage Parkinsons disease in early stages ✓✓ CORRECT ANSWER Either with Pramipexole (mirapex) OR
Rotigotine (Neupro)
2. What is the most effective therapy for PD ✓✓ CORRECT ANSWER Combination therapy with levodopa/carbidopa or
levodopa/carbidopa/entacapone
3. What medications are used to treat off times including wearing off experi-ences ✓✓ CORRECT ANSWER Dopamine
agonists, COMT inhibitors and MAO-B inhibitors.
Entacapone-COMT- inhibitor
Rasagiline- MAO- B inhibitor
4. Adverse effects of Pramipexole ✓✓ CORRECT ANSWER Nausea, dizziness, daytime somnolence, insomnia, constipation, weakness, and
hallucinations, impulse control disorders
5. Which medication is the safest choice for someone on oral contraceptive ✓✓ CORRECT ANSWER -
Pregabalin
6. What is the purpose and timing of serum drug levels ✓✓ CORRECT ANSWER small changes in dosage produce large changes
in plasma levels, as a result small increases in dosage can cause toxicity and small decreases can cause therapeutic failure. this relationship makes it diflcult to establish and
maintain a dosage that is both safe and ettective. for this reason, serum drug levels and trough levels are often used along with assessments of seizure control o determine dosage.
7. Phenytoin drug interactions ✓✓ CORRECT ANSWER Oxcarbazepine inhibits the enzymes that metabolize phenytoin thus
raising phenytoin. Controversially phenytoin may decrease serum concentrations of oxcarbazepine
8. What can happen when you take phenytoin and oxcarbazepine together-
✓✓ CORRECT ANSWER phenytoin toxicity and subtherapeutic levels of oxcarbazepine can occur. These levels should be monitored and dosages adjusted accordingly.
9. What is first line therapy for migraines and headaches? ✓✓ CORRECT ANSWER OTC medications such as Tylenol and
Advil
10. What medications can help prevent migraine attacks ✓✓ CORRECT ANSWER Propranolol metoprolol and 3 beta blockers-
timolol, atenolol and nadolol
11. what drugs can cause medication overuse headache ✓✓ CORRECT ANSWER almost all medications used for abortive
headache therapy ✓✓ CORRECT ANSWER aspirin-like drugs, opioids, triptans, ergotamine- but not dihydroergotamine, and catteine
12. What measures can decrease MOH ✓✓ CORRECT ANSWER limit use of abortive medications. patient should not take these drugs no more
than 2-3 times a week and doses should not be higher than actually needed
, 13. What are contraindications for sumatriptan ✓✓ CORRECT ANSWER all triptans are contraindicated for patients with ischemic heart
disease, prior MI or uncontrolled HTN
14. What are alternative medications for migraines ✓✓ CORRECT ANSWER Beta blockers
antiseizure drugs
tricyclic antidepressants
estrogens and triptans for menstrual associated migraines erenumab
botulinum toxin
15. what is the drug of choice for moderate alzheimers disease ✓✓ CORRECT ANSWER cholinesterase inhibitor
✓✓ CORRECT ANSWER Aricept, Razadyne ER and Exelon
16. Is it recommended to combine two cholinesterase inhibitors ✓✓ CORRECT ANSWER no
17. What is memantine indicated for ✓✓ CORRECT ANSWER mild to moderate AD, it is NOT indicated with mild AD as studies have not shown
symptom improvement
18. how is Rivastigmine (Exelon) administered ✓✓ CORRECT ANSWER orally or transdermal patch
19. where does Rivastigmine act on ✓✓ CORRECT ANSWER both acetylcholinesterase and butyrylcholinesterase thereby increasing its
eflcacy.
20. Who should not take rivastigmine ✓✓ CORRECT ANSWER patients with COPD
21. Does Rivastigmine and galantamine require tappering ✓✓ CORRECT ANSWER no
22. what is the recommended starting dose for rivastigmine ✓✓ CORRECT ANSWER 1.5mg BID
23. What is Donepezil approved to tx ✓✓ CORRECT ANSWER moderate to severe AD
24. What dose is Donepezil given ✓✓ CORRECT ANSWER can dose at 23mg/day however there is minimal evidence to show improvement from
10mg to 23mg. 23mg dose has shown to have more adverse ettects
25. Does donepezil require tappering ✓✓ CORRECT ANSWER yes
26. Besides AD what else does donepezil treat ✓✓ CORRECT ANSWER anxiety, depression, apathy, delusions and pacing
27. what is the only NMDA drug approved to manage moderate to severe AD ✓✓ CORRECT ANSWER
Memantine
28. what drug is associated with an increased life expectancy than that of donepezil ✓✓ CORRECT
ANSWER Memantine
29. What are side effects of cholinesterase inhibitors ✓✓ CORRECT ANSWER GI, Dizziness and HAs