NURS 5315 Exam 2: Advanced Pathophysiology Study Guide

NURS 5315 UTA Exam 2 With 100%
Correct And Verified Answers 2025
HIViEIAi(3rdigenerationiimmunoassay)i-
iCorrectiAnswer-

caniuseiurine,isaliva,ioriserumi(mostiaccurate),ineedi
toiwaitiuntili12iweeksipostiexposureitoiseeiantibodies
,i>99%iaccurate
4thigenerationiimmunoassay-i"goldistandard"
measuresiP24iantigen
canitesti10idaysipostiexposure

Masticelli-iCorrectiAnswer-
Cellularibagsiofigranulesilocatediinilooseiconnectivei
tisssueicloseitoibloodivessels.iActivationiinitiatesiinfl
ammatoryiprocess.

Histaminei-iCorrectiAnswer-
Causesivasodilation,iincreasesivascularipermeability
,iincreasesibloodiflowitoitheisiteiofiinjury-
icausesierythemaiandiswelling.



Cytokinesi-iCorrectiAnswer-
Solubleifactorsithaticontributeitoitheiregulationiofiin
nateioriadaptiveiresistanceibyiaffectingiotherineighb
oringicells.iCanibeipro-inflammatoryiorianti-
inflammatory.iCanireactiquicklyioribeimoreidelayed.

Leukotrinesi-iCorrectiAnswer-
Releasediwhenimasticellsidegranulate,iprolongitheiin
flammatoryiprocess.iCauseivasodilation,iattractineut
rophils,imonocytes,iandieosinophils.targetiofiinhibiti
oniforisingular.

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,Prostaglandinsi-iCorrectiAnswer-
Releasediwhenimasticellsidegranulate,iareiproducedi
byitheiarachidonicipathway.iCauseivasodilation,iplate
letiaggregationiatisiteiofiinjury,ipain,iandifever.

Chemotacticifactorsi-iCorrectiAnswer-
Biochemicalisubstanceithatiattractsileukocyteitoithei
siteiofiinflammation

Neutrophilsi-iCorrectiAnswer-
Predominantileukocyteiatiworkiduringitheiearlyistage
siofiacuteiinflammation

Monocytesi-iCorrectiAnswer-
Becomeimacrophagesiwhenienteringitheitissue,iresp
onsibleiforipresentingiantigensitoitheiCD4icelliwhichi
triggersiT-celliimmunityiandiB-celliimmunity.
ReleasesiadditionalicytokinesiIL1,iIL6,iTNF.

CytokineiIL1ifunctioni-iCorrectiAnswer-
Causesifever,iactivatesiphagocytesi&ilymphocytesian
dialsoiincreasesitheireleaseiofiIL6a

CytokineiIL6ifunctioni-iCorrectiAnswer-
Stimulatesiproductioniofiacuteiphaseireactantsiandip
romotesigrowthiandistimulationiofiRBCs

CytokineiTNFifunctioni-iCorrectiAnswer-
Causesifever,iincreasesisynthesisiofiproinflammatory
iproteinsibyiliver,icausesimuscleiwasting,iinducesithr

ombosis




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, Cytokineigrowthifactorifunctioni-iCorrectiAnswer-
Promotesiproductioniandimaturationiofineutrophils

Complementi-iCorrectiAnswer-
Functionsiincludeibacterialilysis,ivasodilationiandiin
creasedivascularipermeability,itriggersimasticellideg
ranulation,ichemotaxis,iandiopsonization.

Kinini-iCorrectiAnswer-
Converteditoibradykininiwhichiisiresponsibleiforipaini
andichemotaxis,iandiitiincreasesivascularipermeabili
tyiandivasodilation.

Coagulationicascadei-iCorrectiAnswer-
FactoriXIIiactivatesikinin.iFunctioniisitoiformifibrinim
eshitoistopibleedingianditrapimicroiorganisms.

COX1i-iCorrectiAnswer-
Prostaglandiniofiarachidonicipathway.iProvidesigast
roprotection,iplateletiaggregation,ifluid/
electrolyteibalance

COX2i-iCorrectiAnswer-
Prostaglandiniofiarachidonicipathway.iResponsibleif
oripain,ifever,irenaliprotection,itissueirepair,ireprodu
ctionidevelopment.

COX2iinhibitors-iclinicaliimplicationsi-
iCorrectiAnswer-Protectigastricimucosa-

ipreventiulcersiandibleeding.iRemovedifromimarketir/

ticardiacieventsiexceptiforiCelebrex.iCaniimpairirenali
functioni,imonitorilabs.




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