Ch.5 Epidemiology of Communicable Date
disease Page 24
SiN * S Chicken pox ( Vasicala)
Cause Varicalla-Zostervius
Chaxacterized by vesicular rash that may be
accompanied by fever e malaise
ÇPxoblem statement
Compae1-3per 1000 measles
It affect infant, pregnant women
& others
Adut.
Media -2013- 450,090 Cases of chickenpox
-all death
.epidemiotogicad determinant5
SAgent factoxs
Agenti Causałive agent: Human herpes vius
infection în canial nerve , Sensoryganglia,
and spinal dorsal TOot ganglia.
is painful yesicular pustular exuption.
in. the. distzibution of one more
Sensory nerve Yoot
SouTCe ofinteetion : OYopharyngeal secretion
and lesions of skin and mucosa
O ofectivity to 2 day befove the
appearance of Tash & 4 to 5 day
there after.
, Date
Page 25
Decondary attack ate: 40%.
Host factors
@)Age- child under 10 yos.
O_Immunity
nity
Ome attack gives dua able immu
Second attack tare. (cell - mediated
immunity )
Focus leading to congenital
varicella syndvome.
(infection dusing 20 week of gestation)
Envixonmental factos :
wintes spring in coolest , driest
month
VZV is heat labile.
Out side host cell vivous service in envivoment
in fes da.
:Transmission ::
Person to person by droplet infection
('face to face' contact)
entry → upper Respi track Conjunctiva.
vivous Can CTOSs placental basvier and
infect the foetus.
Incubation pesiod}: 14 to 16
day
Cinical features : :
CA) : Pre - eruptive stage : mild or moderate
fever,24 pain
ha.
in back, shivezing, malaise
disease Page 24
SiN * S Chicken pox ( Vasicala)
Cause Varicalla-Zostervius
Chaxacterized by vesicular rash that may be
accompanied by fever e malaise
ÇPxoblem statement
Compae1-3per 1000 measles
It affect infant, pregnant women
& others
Adut.
Media -2013- 450,090 Cases of chickenpox
-all death
.epidemiotogicad determinant5
SAgent factoxs
Agenti Causałive agent: Human herpes vius
infection în canial nerve , Sensoryganglia,
and spinal dorsal TOot ganglia.
is painful yesicular pustular exuption.
in. the. distzibution of one more
Sensory nerve Yoot
SouTCe ofinteetion : OYopharyngeal secretion
and lesions of skin and mucosa
O ofectivity to 2 day befove the
appearance of Tash & 4 to 5 day
there after.
, Date
Page 25
Decondary attack ate: 40%.
Host factors
@)Age- child under 10 yos.
O_Immunity
nity
Ome attack gives dua able immu
Second attack tare. (cell - mediated
immunity )
Focus leading to congenital
varicella syndvome.
(infection dusing 20 week of gestation)
Envixonmental factos :
wintes spring in coolest , driest
month
VZV is heat labile.
Out side host cell vivous service in envivoment
in fes da.
:Transmission ::
Person to person by droplet infection
('face to face' contact)
entry → upper Respi track Conjunctiva.
vivous Can CTOSs placental basvier and
infect the foetus.
Incubation pesiod}: 14 to 16
day
Cinical features : :
CA) : Pre - eruptive stage : mild or moderate
fever,24 pain
ha.
in back, shivezing, malaise
