TEST BANK For Psychopharmacology: Drugs, the Brain, and Behavior, 4th Edition By Meyer Nursing, Verified Chapters 1 - 20, Complete Newest Version

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, Test Bank 0#


to accompany
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Psychopharmacology, Fourth Edition 0# 0#


Meyer • Quenzer 0# 0#




Chapter 1: Principles of Pharmacology 0# 0# 0# 0#




Multiple Choice 0#




1. 0#


refer(s) to specific molecular changes that occur when a drug binds to a particular
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target site or receptor, while
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are the resulting widespread alterationsin function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects 0# 0# 0#


d. Drug action; drug effects
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Answer: d 0#


Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free
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tobind at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. 0#


c. bioavailability.
d. ED50.
Answer: c 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target
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siteor receptor are referred to as
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a. drug effects. 0#


b. drug action. 0#


c. side effects. 0#


d. placebo effects. 0#


Answer: b 0#


Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning 0#


b. Genetic variation 0#


c. Drug competition 0#


d. Expectation of outcome 0# 0#


Answer: c 0#


Textbook Reference: Pharmacology: The Science of Drug Action
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,5. The administration of oxytocin has been proposed as a treatment for autism. 0# 0# 0# 0# 0# 0# 0# 0# 0# 0#


a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration
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b. Lipid solubility
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c. Depot binding 0#


d. Drug action 0#


Answer: d 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken
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a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
0# 0# is not complete.
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a. cerebrospinal fluid 0#


b. blood–brain barrier 0#


c. choroid plexus 0#


d. phospholipid membrane 0#


Answer: b 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the wa
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y togeneral circulation.
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0 0#


c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. 0#


b. choroid plexus. 0#


c. area postrema.
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d. median eminence. 0#




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, Answer: c 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ 0# have the most rapid onset of action. 0# 0# 0# 0# 0# 0# 0#


a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the
0# of the solution and the
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of thedrug.
0# 0#


a. pH; pKa
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b. pKa; pH 0#


c. concentration; lipid solubility 0# 0#


d. pH; concentration
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Answer: a 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
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b. ionization.
c. body temperature.
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d. the concentration of the drug.
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Answer: c 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are 0#should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble
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Answer: a 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactive drugs. 0#


b. illicit drugs.
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c. teratogens.
d. placental drugs. 0#


Answer: c 0#


Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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