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NCLEX PHARMACOLOGY COMPLETE STUDY GUIDE 2026 | PRACTICE QUESTIONS & ANSWERS

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This NCLEX Pharmacology Complete Study Guide 2026 is a comprehensive nursing exam preparation resource designed to help students master essential pharmacology concepts tested on the NCLEX-RN. It includes practice questions with clear answers covering drug classifications, mechanisms of action, side effects, adverse reactions, contraindications, and nursing responsibilities for safe medication administration.

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Institution
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NCLEX PHARMACOLOGY COMPLETE STUDY
GUIDE 2026 | PRACTICE QUESTIONS &
ANSWERS
| GRADED A+ | GUARANTEED SUCCESS




Updated 2026 Questions and Answers

100% Verified Exam Prep and Comprehensive
Rationales Included

,A client diagnosed with new onset atrial fibrillation has 2. Do not take with clopidogrel.
been prescribed dabigatran. What should the nurse teach
this client? 3. Dabigatran decreases the risk of stroke associated with atrial fibrillation.
Select all that apply
4. Take this medication with food.
1. Place medication in a weekly pill organizer so that
medication is not forgotten. (2., 3., & 4. Correct: Do not take dabigatran with any other anticoagulants,
including clopidogrel due to increased bleeding risk. Dabigatran decreases the
2. Do not take with clopidogrel. risk of stroke and systemic embolism in clients with atrial fibrillation that is not
associated with a cardiac valve problem. Take this medication with food to
3. Dabigatran decreases the risk of stroke associated with decrease gastric side effects such as dyspepsia and gastritis. Proton pump
atrial fibrillation. inhibitors and histamine 2 recepter blockers may also decrease gastric side
effects.
4. Take this medication with food.
1. Incorrect: After container is opened, medication should be used within 30 days.
5. aPTT and INR levels will be drawn monthly. It is sensitive to moisture and should not be stored in weekly pill organizers. To
maintain efficacy, keep medication in manufacturer- supplied bottle.


5. Incorrect: This medication does not require monitoring of INR levels. However,
the client should be informed about the risk of bleeding and to monitor for signs
of bleeding.)


A client has a prescription for nitroglycerin gr 1/400 SL 0.5
prn for angina pain. How many tablets should the nurse
give the client? Use numbers and decimals only. (Rationale:


Nitroglycerin tablets, USP (0.0025 gr ÷ 1) × (0.3 mg ÷ 0.005 gr) × (1 tab ÷ 0.3 mg) = (0.00075 ÷ 0.0015) = 0.5 tab
Rx Only
0.3 mg (1/200 gr) Ans: 0.5 tab)
100 Sublingual Tablets


Ans:______

,A client has been started on intravenous gentamicin for 4. Peak and trough levels.
osteomyelitis. The nurse informs the client frequent blood
work will be done to monitor the amount of medication in (4. Correct: Peak and trough levels help to determine the amount of medication in
the body. The nurse knows what labs are a priority to the body system at specific times. Gentamicin is a very potent antibiotic; therefore,
check every three days for the client? it is crucial to keep track of blood levels of this medication. Too low a level of this
drug would be ineffective against the bacteria while too high a level increases the
1. BUN and creatinine. potential for severe side effects or toxicity from this antibiotic.


2. Liver function studies. 1. Incorrect: Because aminoglycosides such as gentamicin can lead to
nephrotoxicity, checking BUN and creatinine levels periodically is important.
3. Hemoglobin and hematocrit. However, it would not be necessary to check those values every three days.


4. Peak and trough levels. 2. Incorrect: Aminoglycosides like gentamicin rarely affect the liver; therefore, liver
function studies would not be needed frequently.


3. Incorrect: Hemoglobin and hematocrit levels are rarely impacted by
aminoglycosides such as gentamicin. Although an initial level may be obtained
prior to treatment, additional levels are not necessary.)


The nurse is preparing to give a client's prescribed 2.5
furosemide dose. How many mL will the nurse give to the
client? Answer to the first decimal place. Answer with (Rationale:
numbers and decimal only.
(25 mg ÷ 1) × (1 mL ÷ 10 mg) = (25 ÷ 10) = 2.5 mL
Perscription:
Furosemide 25 mg by mouth daily Ans: 2.5 mL)


Furosemide Oral Solution USP
10 mg per mL
Each mL contains 10 mg furosemide USP.
SUGAR FREE


Ans:______


A teenager leaves class in the middle of an exam to go to 2. "Have you been drinking energy drinks while studying for your exam?"
the school nurse's office. The student reports difficulty
sleeping for several days, increasing nervousness, (2. Incorrect: Caffeine is a stimulant used to keep people awake and increase
irritability, and palpitations. The nurse notes flushing of energy. It is found in many OTC medications and in many soft drinks and energy
the skin, and an irregular heartbeat. What would be the drinks. The student is exhibiting all the signs/symptoms of ingesting too much
best question for the nurse to ask this client? caffeine.


1. "Do you feel this way because you are afraid that you 1. Incorrect: This is not addressing the problem. These are physical symptoms of a
are failing the exam?" problem.


2. "Have you been drinking energy drinks while studying 3. Incorrect: This is confrontational and will put the student on the defensive.
for your exam?" Caffeine is not generally thought of as a drug by clients, so might not even be
considered in the first place.
3. "What drugs are you taking?"
4. Incorrect: This might be done later, but this question does not help to
4. "Do you want me to call your mother?" determine what is going on with the student.)

, The nurse is reinforcing the dietary discharge instruction 3. Spinach
for a client prescribed warfarin. Which food choices
should be avoided on the warfarin dietary instruction 4. Broccoli
plan?
Select all that apply (3. & 4. Correct: Clients prescribed warfarin will need to reduce the intake of food
sources with high levels of vitamin K. High levels of vitamin K interfere with
1. Corn warfarin by decreasing the effectiveness of warfarin to prevent blood clots. The
vitamin K level of 1 cup of raw spinach is 144.87 mcg. The vitamin K level of 1 cup of
2. Carrot raw broccoli is 92.46 mcg. Because spinach and broccoli are high in vitamin K, the
client should eat sparingly or refrain from eating spinach, and broccoli.
3. Spinach
1. Incorrect: There is 0.31 mcg of Vitamin K in 1.0 ear, medium (6-3/4" to 7-1/2" long)
4. Broccoli of corn. This level of vitamin K in the corn can be consumed with warfarin. The
vitamin K level of corn will not interfere with the action of warfarin.
5. Watermelon
2. Incorrect: The level of vitamin K in a cup of raw carrots is 16.9 mcg. Carrots will
not reduce the action of warfarin, due to the low level of vitamin K in corn.


5. Incorrect: The content of vitamin K in a cup of watermelon is 0.15 mcg. Due to
the low level of vitamin K in watermelon. Watermelon will not lower the
effectiveness of warfarin.


The nurse is preparing to give a client's prescribed 3.6
ceftazidime dose. How many mL will the nurse give to the
client? Answer to the first decimal place. Answer with (Rationale:
numbers and decimal only.
Prescription: Ceftazidime 1 gm IM every 6 hours
Perscription: Available: Ceftazidime 1 gm in 3.6 mL
Ceftazidime 1 gm IM every 6 hours Step 1: The instructions say to add 3.0 mL sterile water for injection to the vial.
Volume yields 3.6 mL.)
Tazicef
Ceftazidime For Injection, USP
For IM injection, IV direct (bolus) injection, or IV infusion,
reconstitute with Sterile Water for injection according to
the following information. The vacuum may assist entry of
the diluent. SHAKE WELL.


Vial Size → Diluent to Be Added → Approx. Avail. Volume
Intramuscular or Intravenous Direct (bolus) Injection:
1 gram → 3.0 mL → 3.6 mL
Intravenous Infusion:
1 gram → 10 mL → 10.6 mL
2 gram → 10 mL → 11.2 mL


Ans:______

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