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NGN ATI Pharmacology 2026 Proctored Exam and Study Guide – 100 Questions with Detailed Verified Answers and Rationales

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This document provides a comprehensive study guide for the NGN (Next Generation NCLEX) Assessment Technologies Institute Pharmacology Proctored Exam, updated for 2026, with 100 practice questions and detailed answer rationales. It covers high-yield pharmacology topics including medication classifications, mechanisms of action, therapeutic uses, adverse effects, contraindications, priority nursing interventions, and NGN-style clinical judgment scenarios. The material is designed to support focused revision, strengthen pharmacology knowledge, and enhance clinical reasoning for proctored exam preparation and nursing success.

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Institution
NURS 1140
Course
NURS 1140

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NGN ATI PHARMACOLOGY 2026 PROCTORED EXAM AND
STUDY GUIDE 100 QUESTIONS WITH DETAILED VERIFIED
ANSWERS AND RATIONALE A+ GRADE
A nurse is providing teaching to a client who has UTI and new prescription for
phenazopyridine and ciprofloxacin. Which of the following statements by the client
indicates the need for further teaching?


a. If the phenazopyridine upsets my stomach, I can take it with meals.

b. The phenazopyridine will relieve my discomfort, but the cipro will get rid of the
infections.


c. I need to drink2 liters of fluid per day while I am taking cipro.

d. I should notify my provider immediately if my urine turns an orange color. -
...ANSWER...d. I should notify my provider immediately if my urine turns an orange
color.

A nurse is caring for an older adult client who has a prescription for zolpidem at bedtime to
promote sleep. The nurse should plan to monitor the client for which of the following
adverse effects?
a. Ecchymosis
b. Decreased urine output
c. Increased blood pressure
d. Dizziness - ...ANSWER...d. Dizziness
A nurse is reviewing laboratory values for a client who reports fatigue and cold intolerance.
The client has an increased thyroid stimulating hormone (TSH) level and a decreased total T3
and T4 level. The nurse should anticipate a prescription for which of
the following medications?


a. Methimazole
b. Somatropin
c. Levothyroxine
d. Propylthiouracil - ...ANSWER...c. Levothyroxine
A nurse is providing teaching to a client who has a new prescription for
hydrochlorothiazide 50mg po daily to treat hypertension. Which of the following
instructions should the nurse include in the teaching?


a. Take the hydrochlorothiazide as needed for edema

,b. Check your weight once each week

c. Take the hydrochlorothiazide on an empty stomach

d. Take the hydrochlorothiazide in the morning. -
...ANSWER...d. Take the hydrochlorothiazide in the morning.
A nurse is caring for a client who is at 28 weeks of gestation and is experiencing preterm
labor. Which of the following medications should the nurse plan to administer?
a. Oxytocin
b. Nifedipine
c. Dinoprostone
d. Misoprostol - ...ANSWER...b. Nifedipine
A nurse is providing teaching to a client who has cirrhosis and new prescription for lactulose.
The nurse should instruct the client that lactulose has which of the following therapeutic
effects?

a. Increases blood pressure
b. Prevents esophageal bleeding
c. Decreases heart rate
d. Reduce ammonia levels - ...ANSWER...d. Reduce ammonia levels
A nurse is caring for an older adult client who has a new prescription for amitriptyline to treat
depression. Which of the following diagnostic tests should the nurse plan to perform prior to
starting the client on this medication?

a. Hearing examination
b. Glucose tolerance test
c. Electrocardiogram
d. Pulmonary function test - ...ANSWER...c. Electrocardiogram
A nurse is providing teaching to a client who has gout and new prescription for
allopurinol. The nurse should instruct client to discontinue taking the medications for
which of the following adverse effects?
a. Nausea
b. Metallic taste
c. Fever
d. Drowsiness - ...ANSWER...c. Fever

A nurse is assessing a client who is receiving IV gentamicin 3 x daily. Which of the
following findings indicates that the client is experiencing an adverse effect of this
medication?

,a. Hypoglycemia
b. Proteinuria
c. Nasal congestion
d. Visual disturbances - ...ANSWER...b. Proteinuria
A nurse is providing teaching to a newly nurse about caring for a client who has
prescription for gemfibrozil. The nurse should instruct the newly licensed nurse to monitor
which of the following lab tests?
a. Platelet count
b. Electrolyte levels
c. Thyroid functions
d. Liver function - ...ANSWER...d. Liver function
A nurse is caring for a client who has a new prescription for ergotamine. The nurse should
recognize that ergotamine is administered to treat which of the following conditions?
a. Raynaud's phenomenon
b. Migraine headaches
c. Ulcerative colitis
d. Anemia - ...ANSWER...b. Migraine headaches
A nurse is reviewing the lab values for a client who is receiving a continuous IV heparin
infusion and has an aPTT (TR-60-80 sec) of 90 seconds. Which of the following actions
should the nurse prepare to take?

a. Administer Vit K
b. Reduce the infusion rate
c. Give the client a low dose aspirin
d. Request an INR - ...ANSWER...b. Reduce the infusion rate
A nurse is providing teaching to a client who had rheumatoid arthritis and a prescription for
long term prednisone therapy. The nurse should instruct the client to monitor for which of
the following adverse effects?

a. Stress fractures
b. Orthostatic hypotension
c. Gingival ulcerations
d. Weight loss - ...ANSWER...a. Stress fractures
A nurse is caring for a client who has a new prescription for tamoxifen. The nurse should
recognize that tamoxifen has which of the following therapeutic effects?
a. Antiestrogenic
b. Antimicrobial

, c. Androgenic
d. Anti-inflammatory - ...ANSWER...a. Antiestrogenic
A nurse is caring for a client who has a new prescription for amphotericin B. The nurse
should plan to monitor the client for which of the following adverse effects?


a. Hyperkalemia
b. Hypertension
c. Constipation
d. Nephrotoxicity - ...ANSWER...d. Nephrotoxicity
A nurse is administering subQ heparin to a client who is at risk for DVT. Which of the
following should the nurse take?


a. Administer the medication into the client's abdomen

b. Inject the medication into a muscle
c. Massage the site after administering the medication

d. Use a 22 gauge needle to administer the medication -
...ANSWER...a. Administer the medication into the client's abdomen

A nurse is reviewing the lab results for a client who has prescription for filgastrim. The nurse
should recognize that an increase in which of the following values indicates a therapeutic
effect of this medication?

a. Erythrocyte count
b. Neutrophil count
c. Lymphocyte count
d. Thrombocyte count - ...ANSWER...b. Neutrophil count
A nurse is providing teaching to a client who has ulcerative colitis and a new prescription
for sulfasalazine. The nurse should instruct the client to monitor for which of the following
adverse effects of this medication?

a. Jaundice
b. Constipation
c. Oral candidiasis
d. Sedation - ...ANSWER...a. Jaundice

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Course
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