TOPICS AND SOLUTIONS
CROSSMATCHING AND DONOR TESTING
GUIDE
◉ If a patient has anti-Fy(a) in his serum, he must receive red blood
cells that are negative for the Fy(a) antigen. What percent of the
Caucasian population is negative for the Fy(a) antigen
Answer: 35%
◉ If a person has the Le, se and H genes, what substance(s) are in
his body fluids
Answer: Only Le(a) blood group substance
◉ Select the cell below that should be used for the positive control
when testing commercially prepared anti-Fy(a)
Answer: Fy(a+b+)
◉ What do the following antigens have in common Js(b), U, I, Yt(a)
Answer: All are high frequency antigens
, ◉ What do the following antibodies have in common Anti-N, anti-P1,
anti-Le(a)
Answer: All are considered clinically insignificant
All are usually IgM
◉ What do the following antigens have in common Fy(a), M, N, S
Answer: All are destroyed when treated with an enzyme
◉ What do the following antigens have in common k, Kp(b), Js(b)
Answer: All are antigens in the Kell Blood Group System
All are high frequency antigens.
All are destroyed when treated with a thiol-reducing agent.
◉ Which of the following antibodies reacts best in an acidic
environment
Answer: Anti-M
◉ Which of the following blood group systems produces antibodies
that do not cause hemolytic disease of the newborn
Answer: Lewis
◉ Which of the following antibodies reacts with the same strength
through all dilutions of the serum until it becomes negative