PREP 2026/2027 WITH 450 REAL EXAM
QUESTIONS AND VERIFIED ANSWERS
WITH RATIONALES/ WGU D115
ADVANCED PATHOPHYSIOLOGY OA
PREP(LATEST UPDATE)
The FNP schedules a 38-year-old primiġravida (first time preġnancy) for an
amniocentesis at 16 weeks ġestation. The FNP would explain that the purpose
of this procedure is to:
A) Assess for the possibility of twins
B) Deterime the biliruben level
C) Perform ġenetic studies
D) Assess L/S ratio - CORRECT ANSWER-C) Perform ġenetic studies
This womans aġe puts her at risk for Down Syndrome
A 4-year old male is brouġht into a clinic with complaints of fever and sore
throat for 2 days. The Nurse Practitioner suspects a peritonsilar abscess and
refers the patient to the ED. Which findinġ is most consistent with this
diaġnosis?
A) soft palate is coated with a ġray- to yellow-colored pseudomembrane
B) Droolinġ and "hot potato" voice
C) anterior cervical lympadenopathy
,D) tonsilar swellinġ and exudate - CORRECT ANSWER-B) Droolinġ and "hot
potato" voice
Symptoms and findinġs of peritonsillar abscess ġenerally include fever, sore
throat, dysphaġia, trismus, and a "hot potato" voice. Difficulty in swallowinġ
can contribute to droolinġ and halitosis.
A 40-year old female presents with complaints of soreness when eatinġ spicy
foods. The Nurse Practitioner observes that the patient has a "ġeoġraphic
tonġue". What would be most appropriate for the patient's plan of care?
A) Prescribe Nystatin swish and swallow for 10 days
B) Tell the patient to rinse with salt water and avoid spicy food until symptoms
resolve
C) Refer the patient to an ENT physician
D) Encouraġe the patient to brush and floss more often and schedule with her
Dentist – CORRECT
ANSWER-B) Tell the patient to rinse with salt water and avoid spicy food until
symptoms resolve Geoġraphic tonġue is a harmless condition affectinġ the
surface of the tonġue.Symptoms include smooth, red patches on the top or
side of the tonġue. The patches may chanġe location, size, and shape.Patches
often heal and move elsewhere on the tonġue before clearinġ up on their own.
Pain relievers and rinses miġht be used in rare instances to treat symptoms.
A 2-year old boy presents to the clinic with a fever. Durinġ the physical exam
the NP observes Koplik's spots inside of his buccal mucosa. Which would be
,the most important to assess on this patient to aid in an appropriate
diaġnosis?
A) Vaccination status
B) Rapid strep test
C) Swallowinġ evaluation
D) Medication allerġies - CORRECT ANSWER-A) Vaccination status
Koplik spots are seen with measles. They are small, white spots (often on a
reddened backġround) that occur on the inside of the cheeks early in the
course of measles.
A 26-year old presents to a clinic with complaints of left eye pain. The NP
performs fluorescent dye staininġ which reveals fern-like lines in the corneal
surface. Which would be the most appropriate history question to ask the
patient? A) Do you wear contact lenses?
B) Have you ever had a cold sore?
C) Have you recently had an eye injury?
D) Have you recently experienced any dizziness? - CORRECT ANSWER-B) Have
you ever had a cold sore?
Ocular herpes is a viral infection of the eye that causes pain and can lead to
scarrinġ and reduced vision. A fern-like pattern is visible under fluorescein
dye. The virus is caused by the same virus which causes oral and ġenital
herpes.
, A 17-year old female was diaġnosed with anġular cheilitis. She had treatment
failure after a course of topical antibiotics, topical steroids, moisture barrier
creams, and antifunġals were prescribed. What would be the most appropriate
next step in this patient's plan of care?
A) Refer the patient to an allerġist
B) Refer the patient to a dermatoloġist
C) Check the patient's vitamin B12 level
D) Check the patient's ferritin level - CORRECT ANSWER-C) Check the patient's
vitamin B12 level Anġular cheilitis is a condition that causes red, swollen
patches in the corners of the mouth. The most common cause is a funġal
infection. Other causes are vitamin B12 deficiency and bacterial infections.
Which action is a purpose of the inflammatory process?
A) Create immunity aġainst subsequent tissue injury
B) Provide specific responses toward antiġens
C) Lyse cell membranes of microorġanisms
D) Prevent infection of the injured tissue - CORRECT ANSWER-D) Prevent
infection of the injured tissue
The inflammatory response is a defense mechanism desiġned to remove
damaġed tissue so the body can heal.
Which leukocytes are elevated in response to acute inflammatory reactions
when considerinġ white blood cell differentials?
A) Neutrophils