BMB 252 Final Exam – Study Guide, Practice Questions & Comprehensive
Revision
Which of the following binds to an extracellular signal?
Effector protein
Receptor
Intracellular signaling molecules
Both 2 and 3 - ANS ✔✔Receptor
Some signal transduction proteins are similar (homologous) in yeast and human.
True
False - ANS ✔✔True
Which of the following is not a signaling molecule?
Gas CO
Nucleotide
Steroid
Neurotransmitte
All of the above can be signaling molecules - ANS ✔✔All of the above can be signaling
moleculES
Some signaling molecules can travel through the cellular membrane and bind to their targets
inside the cell.
True
False - ANS ✔✔True
Which of the following signaling types can be used to guide cell movement?
,paracrine
synaptic
Endocrine
Contact-dependent
Both 1 and 4 - ANS ✔✔Both 1 and 4
Lymphocytes have receptors for their own signals that result in their self-activation as well. This
type of signaling is
Autocrine
Endocrine
Synaptic
Paracrine - ANS ✔✔Autocrine
Neurotransmitters have higher affinity to their receptors than hormones.
True
False - ANS ✔✔False
If a cell receives no signals, it will die.
True
False - ANS ✔✔True
Which signal is transduced faster?
The one that involves a new protein synthesis
The one that changes the protein modification state - ANS ✔✔The one that changes the
protein modification state
Acetylcholine always causes muscles to contract
,True
False - ANS ✔✔False
Acetylcholine binds only to one type of receptor
True
False - ANS ✔✔False
Ion pumps pump signals back into _______ to clear the synapse
Presynaptic cell
Postsynaptic cell - ANS ✔✔Presynaptic cell
Which of the following is reversible?
Receptor sequestration
Receptor down-regulation - ANS ✔✔Receptor sequestration
Which feedback loop can result in oscillation?
positive
negative - ANS ✔✔negative
Ion channel linked receptors are mostly located on
At synapses on presynaptic neurons
At synapses on postsynaptic neurons
On the axons
Both B and C - ANS ✔✔At synapses on postsynaptic neurons
Autocrine signaling is analogous to___
, A telephone conversation
Talking to people at a cocktail party
A radio announcement
Talking to yourself - ANS ✔✔Talking to yourself
The ligand molecule for the ion channel-coupled receptor is
Neurotransmitter
K+
Na+ - ANS ✔✔Neurotransmitter
GPCR transmits the signal by
-prosphorylating G protein
-binding G protein and changing its conformation so that it dissociates GDP - ANS ✔✔binding G
protein and changing its conformation so that it dissociates GDP
there is a different GPCR for each smell
- true
-false - ANS ✔✔- true
G protein can activate
-an enzyme
-an ion channel
-a transcriptional activator
-both an enzyme and an ion channel - ANS ✔✔both an enzyme and an ion channel
the subunit of G protein that has GTPase activity is
Revision
Which of the following binds to an extracellular signal?
Effector protein
Receptor
Intracellular signaling molecules
Both 2 and 3 - ANS ✔✔Receptor
Some signal transduction proteins are similar (homologous) in yeast and human.
True
False - ANS ✔✔True
Which of the following is not a signaling molecule?
Gas CO
Nucleotide
Steroid
Neurotransmitte
All of the above can be signaling molecules - ANS ✔✔All of the above can be signaling
moleculES
Some signaling molecules can travel through the cellular membrane and bind to their targets
inside the cell.
True
False - ANS ✔✔True
Which of the following signaling types can be used to guide cell movement?
,paracrine
synaptic
Endocrine
Contact-dependent
Both 1 and 4 - ANS ✔✔Both 1 and 4
Lymphocytes have receptors for their own signals that result in their self-activation as well. This
type of signaling is
Autocrine
Endocrine
Synaptic
Paracrine - ANS ✔✔Autocrine
Neurotransmitters have higher affinity to their receptors than hormones.
True
False - ANS ✔✔False
If a cell receives no signals, it will die.
True
False - ANS ✔✔True
Which signal is transduced faster?
The one that involves a new protein synthesis
The one that changes the protein modification state - ANS ✔✔The one that changes the
protein modification state
Acetylcholine always causes muscles to contract
,True
False - ANS ✔✔False
Acetylcholine binds only to one type of receptor
True
False - ANS ✔✔False
Ion pumps pump signals back into _______ to clear the synapse
Presynaptic cell
Postsynaptic cell - ANS ✔✔Presynaptic cell
Which of the following is reversible?
Receptor sequestration
Receptor down-regulation - ANS ✔✔Receptor sequestration
Which feedback loop can result in oscillation?
positive
negative - ANS ✔✔negative
Ion channel linked receptors are mostly located on
At synapses on presynaptic neurons
At synapses on postsynaptic neurons
On the axons
Both B and C - ANS ✔✔At synapses on postsynaptic neurons
Autocrine signaling is analogous to___
, A telephone conversation
Talking to people at a cocktail party
A radio announcement
Talking to yourself - ANS ✔✔Talking to yourself
The ligand molecule for the ion channel-coupled receptor is
Neurotransmitter
K+
Na+ - ANS ✔✔Neurotransmitter
GPCR transmits the signal by
-prosphorylating G protein
-binding G protein and changing its conformation so that it dissociates GDP - ANS ✔✔binding G
protein and changing its conformation so that it dissociates GDP
there is a different GPCR for each smell
- true
-false - ANS ✔✔- true
G protein can activate
-an enzyme
-an ion channel
-a transcriptional activator
-both an enzyme and an ion channel - ANS ✔✔both an enzyme and an ion channel
the subunit of G protein that has GTPase activity is
