HESI A2 Entrance Exam Practice – 260
Questions with Rationales | Math, Reading,
Vocabulary, Grammar, Biology, Chemistry,
Anatomy | Updated 2026
TABLE OF CONTENTS
1. Mathematics (Questions 1–60)
2. Reading Comprehension (Questions 61–90)
3. Vocabulary and General Knowledge (Questions 91–130)
4. Grammar (Questions 131–160)
5. Biology (Questions 161–190)
6. Chemistry (Questions 191–210)
7. Anatomy and Physiology (Questions 211–260)
MATHEMATICS (Questions 1–60)
Question 1 What is 15% of 200?
A. 15 B. 20 C. 25 D. 30
Correct Answer: D Rationale: 15% = 0.15. 0.15 × 200 = 30. Alternatively, 10% of 200 is 20, and
5% of 200 is 10, so 20 + 10 = 30.
Question 2 Solve for x: 3x + 7 = 22
A. 3 B. 5 C. 7 D. 9
Correct Answer: B Rationale: 3x + 7 = 22 → 3x = 15 → x = 5.
Question 3 (Select all that apply) Which of the following are equivalent to 3/4? (Select all that apply)
,A. 0.75 B. 75% C. 6/8 D. 9/12 E. 3/8
Correct Answers: A, B, C, D Rationale: 3/4 = 0.75 = 75% = 6/8 = 9/12. 3/8 (E) is not equivalent.
Question 4 What is the least common denominator (LCD) of 1/3, 1/4, and 1/6?
A. 6 B. 12 C. 18 D. 24
Correct Answer: B Rationale: The denominators are 3, 4, and 6. The LCD is 12 (the smallest
number divisible by all three).
Question 5 A patient drank 240 mL of water, 120 mL of juice, and 60 mL of soup. What was the total
intake in liters?
A. 0.42 L B. 0.420 L C. 4.2 L D. 42 L
Correct Answer: A Rationale: Total mL = 240 + 120 + 60 = 420 mL. 420 mL = 0.42 L.
Question 6 What is the perimeter of a rectangle with length 8 cm and width 5 cm?
A. 13 cm B. 26 cm C. 40 cm D. 80 cm
Correct Answer: B Rationale: Perimeter = 2(length + width) = 2(8 + 5) = 2(13) = 26 cm.
Question 7 What is the area of a triangle with base 10 cm and height 6 cm?
A. 16 cm² B. 30 cm² C. 60 cm² D. 120 cm²
Correct Answer: B Rationale: Area = 1/2 × base × height = 1/2 × 10 × 6 = 30 cm².
Question 8 What is the value of 5³?
A. 15 B. 25 C. 125 D. 625
Correct Answer: C Rationale: 5³ = 5 × 5 × 5 = 125.
Question 9 A nurse needs to administer 250 mg of a medication. The medication is available as 125
mg per tablet. How many tablets should the nurse give?
A. 1 tablet B. 2 tablets C. 3 tablets D. 4 tablets
Correct Answer: B Rationale: 250 mg ÷ 125 mg/tablet = 2 tablets.
Question 10 (Select all that apply) Which of the following are prime numbers? (Select all that apply)
,A. 2 B. 3 C. 4 D. 5 E. 9
Correct Answers: A, B, D Rationale: Prime numbers are divisible only by 1 and themselves. 2, 3,
and 5 are prime. 4 and 9 are composite.
Question 11 What is the greatest common factor (GCF) of 24 and 36?
A. 6 B. 12 C. 18 D. 24
Correct Answer: B Rationale: Factors of 24: 1, 2, 3, 4, 6, 8, 12, 24. Factors of 36: 1, 2, 3, 4, 6, 9, 12,
18, 36. The GCF is 12.
Question 12 What is the next number in the sequence: 2, 4, 8, 16, ___?
A. 20 B. 24 C. 32 D. 64
Correct Answer: C Rationale: The sequence doubles each time: 2 × 2 = 4, 4 × 2 = 8, 8 × 2 = 16, 16
× 2 = 32.
Question 13 A patient is 6 feet 2 inches tall. How many inches tall is the patient?
A. 62 inches B. 66 inches C. 72 inches D. 74 inches
Correct Answer: D Rationale: 6 feet = 6 × 12 = 72 inches. 72 + 2 = 74 inches.
Question 14 What is the ratio of 12 to 18 in simplest form?
A. 2:3 B. 3:2 C. 4:6 D. 6:9
Correct Answer: A Rationale: 12:18 = 12/18 = 2/3 = 2:3.
Question 15 A medication is ordered at 5 mg/kg. The patient weighs 80 kg. How many mg should be
given?
A. 40 mg B. 160 mg C. 400 mg D. 800 mg
Correct Answer: C Rationale: 5 mg/kg × 80 kg = 400 mg.
Question 16 What is the value of ⅝ as a decimal?
A. 0.5 B. 0.6 C. 0.625 D. 0.875
Correct Answer: C Rationale: 5 ÷ 8 = 0.625.
, Question 17 A patient drank 3/4 of a 240 mL glass of water. How many mL did the patient drink?
A. 60 mL B. 120 mL C. 180 mL D. 200 mL
Correct Answer: C Rationale: 3/4 × 240 = 180 mL.
Question 18 What is the mean (average) of 10, 20, 30, 40, and 50?
A. 25 B. 30 C. 35 D. 40
Correct Answer: B Rationale: Sum = 10 + 20 + 30 + 40 + 50 = 150. 150 ÷ 5 = 30.
Question 19 A nurse works 8 hours per day for 5 days per week. How many hours does the nurse
work in 4 weeks?
A. 40 hours B. 80 hours C. 120 hours D. 160 hours
Correct Answer: D Rationale: 8 hours/day × 5 days/week = 40 hours/week. 40 hours/week × 4
weeks = 160 hours.
Question 20 (Select all that apply) Which of the following are equivalent to 0.25? (Select all that
apply)
A. 1/4 B. 25% C. 2/8 D. 3/12 E. 5/20
Correct Answers: A, B, C, D, E Rationale: All are equivalent to 0.25. 1/4 = 0.25, 25% = 0.25, 2/8 =
0.25, 3/12 = 0.25, 5/20 = 0.25.
Question 21 What is 3/5 + 1/4?
A. 4/9 B. 7/20 C. 17/20 D. 12/20
Correct Answer: C Rationale: 3/5 = 12/20, 1/4 = 5/20. 12/20 + 5/20 = 17/20.
Question 22 What is 3/4 × 2/5?
A. 3/10 B. 5/9 C. 6/20 D. 8/15
Correct Answer: A Rationale: 3/4 × 2/5 = 6/20 = 3/10.
Question 23 What is 3/4 ÷ 1/2?
A. 1/2 B. 3/8 C. 3/2 D. 6/4
Correct Answer: C Rationale: 3/4 ÷ 1/2 = 3/4 × 2/1 = 6/4 = 3/2.
Questions with Rationales | Math, Reading,
Vocabulary, Grammar, Biology, Chemistry,
Anatomy | Updated 2026
TABLE OF CONTENTS
1. Mathematics (Questions 1–60)
2. Reading Comprehension (Questions 61–90)
3. Vocabulary and General Knowledge (Questions 91–130)
4. Grammar (Questions 131–160)
5. Biology (Questions 161–190)
6. Chemistry (Questions 191–210)
7. Anatomy and Physiology (Questions 211–260)
MATHEMATICS (Questions 1–60)
Question 1 What is 15% of 200?
A. 15 B. 20 C. 25 D. 30
Correct Answer: D Rationale: 15% = 0.15. 0.15 × 200 = 30. Alternatively, 10% of 200 is 20, and
5% of 200 is 10, so 20 + 10 = 30.
Question 2 Solve for x: 3x + 7 = 22
A. 3 B. 5 C. 7 D. 9
Correct Answer: B Rationale: 3x + 7 = 22 → 3x = 15 → x = 5.
Question 3 (Select all that apply) Which of the following are equivalent to 3/4? (Select all that apply)
,A. 0.75 B. 75% C. 6/8 D. 9/12 E. 3/8
Correct Answers: A, B, C, D Rationale: 3/4 = 0.75 = 75% = 6/8 = 9/12. 3/8 (E) is not equivalent.
Question 4 What is the least common denominator (LCD) of 1/3, 1/4, and 1/6?
A. 6 B. 12 C. 18 D. 24
Correct Answer: B Rationale: The denominators are 3, 4, and 6. The LCD is 12 (the smallest
number divisible by all three).
Question 5 A patient drank 240 mL of water, 120 mL of juice, and 60 mL of soup. What was the total
intake in liters?
A. 0.42 L B. 0.420 L C. 4.2 L D. 42 L
Correct Answer: A Rationale: Total mL = 240 + 120 + 60 = 420 mL. 420 mL = 0.42 L.
Question 6 What is the perimeter of a rectangle with length 8 cm and width 5 cm?
A. 13 cm B. 26 cm C. 40 cm D. 80 cm
Correct Answer: B Rationale: Perimeter = 2(length + width) = 2(8 + 5) = 2(13) = 26 cm.
Question 7 What is the area of a triangle with base 10 cm and height 6 cm?
A. 16 cm² B. 30 cm² C. 60 cm² D. 120 cm²
Correct Answer: B Rationale: Area = 1/2 × base × height = 1/2 × 10 × 6 = 30 cm².
Question 8 What is the value of 5³?
A. 15 B. 25 C. 125 D. 625
Correct Answer: C Rationale: 5³ = 5 × 5 × 5 = 125.
Question 9 A nurse needs to administer 250 mg of a medication. The medication is available as 125
mg per tablet. How many tablets should the nurse give?
A. 1 tablet B. 2 tablets C. 3 tablets D. 4 tablets
Correct Answer: B Rationale: 250 mg ÷ 125 mg/tablet = 2 tablets.
Question 10 (Select all that apply) Which of the following are prime numbers? (Select all that apply)
,A. 2 B. 3 C. 4 D. 5 E. 9
Correct Answers: A, B, D Rationale: Prime numbers are divisible only by 1 and themselves. 2, 3,
and 5 are prime. 4 and 9 are composite.
Question 11 What is the greatest common factor (GCF) of 24 and 36?
A. 6 B. 12 C. 18 D. 24
Correct Answer: B Rationale: Factors of 24: 1, 2, 3, 4, 6, 8, 12, 24. Factors of 36: 1, 2, 3, 4, 6, 9, 12,
18, 36. The GCF is 12.
Question 12 What is the next number in the sequence: 2, 4, 8, 16, ___?
A. 20 B. 24 C. 32 D. 64
Correct Answer: C Rationale: The sequence doubles each time: 2 × 2 = 4, 4 × 2 = 8, 8 × 2 = 16, 16
× 2 = 32.
Question 13 A patient is 6 feet 2 inches tall. How many inches tall is the patient?
A. 62 inches B. 66 inches C. 72 inches D. 74 inches
Correct Answer: D Rationale: 6 feet = 6 × 12 = 72 inches. 72 + 2 = 74 inches.
Question 14 What is the ratio of 12 to 18 in simplest form?
A. 2:3 B. 3:2 C. 4:6 D. 6:9
Correct Answer: A Rationale: 12:18 = 12/18 = 2/3 = 2:3.
Question 15 A medication is ordered at 5 mg/kg. The patient weighs 80 kg. How many mg should be
given?
A. 40 mg B. 160 mg C. 400 mg D. 800 mg
Correct Answer: C Rationale: 5 mg/kg × 80 kg = 400 mg.
Question 16 What is the value of ⅝ as a decimal?
A. 0.5 B. 0.6 C. 0.625 D. 0.875
Correct Answer: C Rationale: 5 ÷ 8 = 0.625.
, Question 17 A patient drank 3/4 of a 240 mL glass of water. How many mL did the patient drink?
A. 60 mL B. 120 mL C. 180 mL D. 200 mL
Correct Answer: C Rationale: 3/4 × 240 = 180 mL.
Question 18 What is the mean (average) of 10, 20, 30, 40, and 50?
A. 25 B. 30 C. 35 D. 40
Correct Answer: B Rationale: Sum = 10 + 20 + 30 + 40 + 50 = 150. 150 ÷ 5 = 30.
Question 19 A nurse works 8 hours per day for 5 days per week. How many hours does the nurse
work in 4 weeks?
A. 40 hours B. 80 hours C. 120 hours D. 160 hours
Correct Answer: D Rationale: 8 hours/day × 5 days/week = 40 hours/week. 40 hours/week × 4
weeks = 160 hours.
Question 20 (Select all that apply) Which of the following are equivalent to 0.25? (Select all that
apply)
A. 1/4 B. 25% C. 2/8 D. 3/12 E. 5/20
Correct Answers: A, B, C, D, E Rationale: All are equivalent to 0.25. 1/4 = 0.25, 25% = 0.25, 2/8 =
0.25, 3/12 = 0.25, 5/20 = 0.25.
Question 21 What is 3/5 + 1/4?
A. 4/9 B. 7/20 C. 17/20 D. 12/20
Correct Answer: C Rationale: 3/5 = 12/20, 1/4 = 5/20. 12/20 + 5/20 = 17/20.
Question 22 What is 3/4 × 2/5?
A. 3/10 B. 5/9 C. 6/20 D. 8/15
Correct Answer: A Rationale: 3/4 × 2/5 = 6/20 = 3/10.
Question 23 What is 3/4 ÷ 1/2?
A. 1/2 B. 3/8 C. 3/2 D. 6/4
Correct Answer: C Rationale: 3/4 ÷ 1/2 = 3/4 × 2/1 = 6/4 = 3/2.
