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NR547 Final Exam Questions and Verified Answers Chamberlain University, Illinois

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NR547 Final Exam Questions and
Verified Answers Chamberlain
University, Illinois
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Medications for depression - Answer: SSRIs

SNRIs

SDRIs

TCAs

MAOIs



SSRIs - Answer: -Action: inhibit 5-HT reuptake

-Examples: citalopram, escitalopram, fluoxetine, paroxetine, sertraline

-Adverse effects:

• nausea

• agitation

• diarrhea

• headache

• weight gain

• sexual side effects



SNRIs - Answer: -inhibit 5-HT reuptake

,-inhibit NE reuptake (↑ energy, focus)

-increase DA in prefrontal cortex (↑ cognition)

-Examples: desvenlafaxine, duloxetine, levomilnacipran, venlafaxine

-Adverse effects:

• elevated blood pressure

• nausea

• sweating

• tremors

• anxiety

• insomnia

• constipation

• anorexia

• sexual dysfunction



SDRIs - Answer: -inhibit DA reuptake (↑alertness, motivation)

-inhibit NE reuptake (↑energy)

-Adverse effects:

• agitation

• headache

• dry mouth

• constipation

• weight loss



TCAs - Answer: -Action: inhibits the reuptake of serotonin and norepinephrine; blocks
norepinephrine, histamine, and acetylcholine receptors

, -Examples: amitriptyline, clomipramine, desipramine, doxepin

-Common Side Effects:

• dry mouth

• constipation

• blurred vision

• urinary retention

• sedation

• weight gain

• hypotension

• tachycardia

• sexual dysfunction



MAOIs - Answer: -Action: increases norepinephrine and serotonin by inhibiting the enzyme
that inactivates it

-Examples: isocarboxazid, phenelzine, tranylcypromine

-Common Side Effects:

• sedation

• dizziness

• sexual dysfunction

• hypertensive crisis



Prescribing pearls: citalopram (Celexa) - Answer: mild antihistamine effects



Prescribing pearls: escitalopram (Lexapro) - Answer: no known drug interactions

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