am Practice Questions And Correct Answers (
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Verified Answers) Plus Rationales 2026|202
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7 Q&A | Instant Download Pdf
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1. Which of the following best describes Type 1 diabetes?
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a) Autoimmune destruction of pancreatic beta cells d d d d d
b) Insulin resistance with relative insulin deficiency
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c) Impaired glucose tolerance only d d d
d) Secondary to other conditions d d d
Answer: a) Autoimmune destruction of pancreatic beta cells Rationale
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: Type 1 diabetes is caused by autoimmune destruction of pancreatic bet
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a cells, leading to absolute insulin deficiency.
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2. The main pathophysiological defect in Type 2 diabetes is:
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a) Autoimmunity
b) Insulin resistance and beta-cell dysfunction
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c) Lack of glucagon d d
, d) Viral infection
d
Answer: b) Insulin resistance and beta-cell dysfunction
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Rationale: Type 2 diabetes involves insulin resistance in tissues along wit
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h progressive beta-cell dysfunction.
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3. Which test is the gold standard for diagnosing diabetes?
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a) Random blood glucose d d
b) Fasting plasma glucose d d
c) Oral glucose tolerance test (OGTT)
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d) HbA1c
Answer: c) Oral glucose tolerance test (OGTT)
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Rationale: OGTT is the most sensitive diagnostic test for diabetes, thoug
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h HbA1c and fasting plasma glucose are also used in practice.
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4. The recommended HbA1c target for most adults with diabetes is:
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a) <8.0%
b) <7.0%
c) <6.0%
d) <7.5%
Answer: b) <7.0% d d
Rationale: Guidelines recommend aiming for HbA1c <7.0% for most adul
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ts, balancing benefits and hypoglycemia risk.
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5. Which of the following is a rapid-acting insulin?
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a) NPH
b) Regular insulin d
, c) Insulin glargine d
d) Insulin lispro d
Answer: d) Insulin lispro
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Rationale: Insulin lispro is a rapid-
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acting analog, while NPH is intermediate, glargine is long-
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acting, and regular is short-acting.
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6. Which oral diabetes medication primarily works by decreasing hepatic
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glucose production?
d
a) Sulfonylureas
b) Metformin
c) DPP-4 inhibitors d
d) SGLT2 inhibitors d
Answer: b) Metformin d d
Rationale: Metformin lowers hepatic glucose production and improves i
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nsulin sensitivity.
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7. Which lifestyle intervention has the greatest impact on glycemic
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control in Type 2 diabetes?
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a) Reducing sodium intake d d
b) Weight management and physical activity
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c) Vitamin supplementation d
d) Increased water intake d d
Answer: b) Weight management and physical activity Rationale:
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Weight loss and regular exercise significantly improve insulin sens
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itivity and glycemic control.
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, 8. What is the recommended carbohydrate distribution for a person with
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diabetes?
a) All carbohydrates at breakfast
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b) Spread evenly throughout meals and snacks
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c) Avoid carbohydrates completely
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d) Carbohydrates only at dinner d d d
Answer: b) Spread evenly throughout meals and snacks
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Rationale: Even distribution helps prevent postprandial hyperglycemia a
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nd supports stable blood glucose control.
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9. Which of the following is a sign of hypoglycemia?
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a) Polyuria
b) Polydipsia
c) Sweating and tremors d d
d) Blurred vision over weeks d d d
Answer: c) Sweating and tremors
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Rationale: Hypoglycemia often presents with adrenergic symptoms such
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d as sweating, tremors, palpitations, and anxiety.
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10. The recommended target for fasting plasma glucose in most
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adults with diabetes is:
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a) 3–5 mmol/L d
b) 4–7 mmol/L d
c) 5–9 mmol/L d
d) 6–10 mmol/L d