Basic and Clinical Pharmacology, 15th Edition by Bertram G. Katzung – Verified Complete Test Bank (Chapters 1–66)

TEST BANK For Basic and Clinical Pharmacology,
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15th Edition by Bertram G. Katzung, Verified
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Chapters 1 – 66
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,Table of Contents
1. Introduction: The Nature of Drugs & Drug Development & Regulation
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2. Drug Receptors & Pharmacodynamics
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3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action
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4. Drug Biotransformation
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5. Pharmacogenomics
6. Introduction to Autonomic Pharmacology Q Q Q


7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs Q Q Q


8. Cholinoceptor-Blocking Drugs Q


9. Adrenoceptor Agonists & Sympathomimetic Drugs Q Q Q Q


10. Adrenoceptor Antagonist Drugs Q Q


11. Antihypertensive Agents Q


12. Vasodilators & the Treatment of Angina Pectoris Q Q Q Q Q Q


13. Drugs Used in Heart Failure
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14. Agents Used in Cardiac Arrhythmias
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15. Diuretic Agents Q


16. Histamine, Serotonin, & the Ergot Alkaloids
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17. Vasoactive Peptides Q


18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
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19. Nitric Oxide
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20. Drugs Used in Asthma
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21. Introduction to the Pharmacology of CNS Drugs Q Q Q Q Q Q


22. Sedative-Hypnotic Drugs Q


23. The Alcohols
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24. Antiseizure Drugs Q


25. General Anesthetics Q


26. Local Anesthetics
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27. Skeletal Muscle RelaxantsQ Q


28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
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29. Antipsychotic Agents & Lithium Q Q Q


30. Antidepressant Agents Q


31. Opioid Agonists & Antagonists
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32. Drugs of Abuse
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33. Agents Used in Cytopenias; Hematopoietic Growth Factors
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34. Drugs Used in Disorders of Coagulation
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35. Agents Used in Dyslipidemia
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36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs,
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Nonopioid Analgesics, &
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Drugs Used in Gout
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37. Hypothalamic & Pituitary Hormones Q Q Q


38. Thyroid & Antithyroid Drugs
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39. Adrenocorticosteroids & Adrenocortical Antagonists Q Q Q


40. The Gonadal Hormones & Inhibitors
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41. Pancreatic Hormones & Antidiabetic Drugs
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42. Agents That Affect Bone Mineral Homeostasis
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43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
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,44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones
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45. Aminoglycosides & Spectinomycin Q Q


46. Sulfonamides, Trimethoprim, & Quinolones Q Q Q


47. Antimycobacterial Drugs Q


48. Antifungal Agents Q


49. Antiviral Agents Q


50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
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51. Clinical Use of Antimicrobial Agents
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52. Antiprotozoal Drugs Q


53. Clinical Pharmacology of the Antihelminthic Drugs
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54. Cancer Chemotherapy
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55. Immunopharmacology
56. Introduction to Toxicology: Occupational & Environmental
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57. Heavy Metal Intoxication & Chelators
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58. Management of the Poisoned Patient Q Q Q Q


59. Special Aspects of Perinatal & Pediatric Pharmacology
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60. Special Aspects of Geriatric Pharmacology
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61. Dermatologic Pharmacology Q


62. Drugs Used in the Treatment of Gastrointestinal Diseases
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63. Therapeutic & Toxic Potential of Over-the-Counter Agents
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64. Dietary Supplements & Herbal Medications
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65. Rational Prescribing & Prescription Writing
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66. Important Drug Interactions & Their Mechanisms
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation

1. A nurse working in radiology administers iodine to a patient who is
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Qhaving a computed tomography (CT) scan. The nurse working on the
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Qoncology unit administers chemotherapy to patients who have cancer.
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At the Public Health Department, a nurse administers a measles-
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mumps- rubella (MMR) vaccine toa 14-month-old child as a routine
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Qimmunization. Which branch of pharmacology best describes the Q Q Q Q Q Q Q


actions of all three nurses?
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A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

, Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses
are involved with clinical pharmacology or pharmacotherapeutics,
which is a branch of pharmacology that deals with the uses of drugs to
treat, prevent, and diagnose disease. The radiology nurse is
administering a drug to help diagnose a disease. The oncology nurse is
administering a drug to help treat adisease. Pharmacoeconomics
includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body
andpharmacokinetics is how the body acts on the body.



2. When involved in phase III drug evaluation studies,
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what responsibilitieswould the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C

Feedback:

Phase III studies involve use of a drug in a vast clinical population in
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Qwhichpatients are asked to record any symptoms they experience
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Qwhile taking thedrugs. Nurses may be responsible for helping collect
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Qand analyze the information to be shared with the Food and Drug
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QAdministration (FDA) butwould not conduct research independently
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Qbecause nurses do not prescribe medications. Use of animals in drug
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Qtesting is done in the preclinical trials. Select patients who are
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involved in phase II studies to participate in studies where the
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participants have the disease the drug is intended to treat. These
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patients are monitored closely for drug action and adverse effects.
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Phase I studies involve healthy human volunteers who are usually
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paid for their participation. Nurses may observe for adverse effects
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and toxicity.
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