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Acute management of acute bipolar II depression - ANSWER-Mood
stabilizers and antipsychotics
Quetiapine monotherapy is recommended first line - Assess response
after 2 weeks of treatment;
Lithium and lamotrigine are second-line options
Acute management of mania or hypomania - ANSWER-Provide initial
management in a tranquil environment with reduced stimuli, and
attempt verbal de-escalation
lithium is effective and should be considered first line
,Other first-line initial options for monotherapy are divalproex sodium or
an atypical antipsychotic including aripiprazole, asenapine, cariprazine,
paliperidone, risperidone, or quetiapine
First-line combination therapies with good evidence include
combinations of lithium or divalproex sodium and an atypical
antipsychotic including risperidone, quetiapine, aripiprazole, or
asenapine.
Adjustment disorder with depressed mood - ANSWER-adjustment
disorder with Depressed Mood, also called Situational Depression, may
sometimes feel nearly as bleak as MDD, but a major difference is that it
does not arise out of the blue.
Rather, situational depression occurs after there is a specific trauma-
divorce, accident, death of loved one, a major life change...
Aggressive management of acute mania - ANSWER-Administration of a
rapidly acting nonoral antipsychotic or benzodiazepine may be
necessary.
Suggested first-line options include intramuscular olanzapine, inhaled
loxapine, or intramuscular lorazepam. [
Antidepressant medications used to treat depressive symptoms -
ANSWER-SSRI
,SNRI
TCS
MAOI's
ASQ screening - ANSWER-The Ask Suicide-Screening Questions (ASQ)
tool is a brief validated tool for use among both youth and adults.
Assessing Depression in Patients with Dementia - ANSWER-Self-
reporting scales, such as the GDS, may be inappropriate.
Cornell Scale for Depression in Dementia can be used to screen not
diagnose.
Bipolar - Sleep disruptions - ANSWER-If there is a suspicion of
obstructive sleep apnea, frequently comorbid with obesity, a sleep
study might be recommended.
Bipolar and related disorder due to another medical condition -
ANSWER-Prominent and persistent disturbance of mood characterized
by elevated, expansive, or irritable mood and abnormally increased
activity or energy that develops as the direct pathophysiological
consequence of another medical condition (e.g. hyperthyroidism,
Cushing syndrome)
Bipolar common comorbidities - ANSWER-Substance misuse disorders,
anxiety disorders,
panic disorders,
attention-deficit disorder,
personality disorder,
, common medical conditions" such as obesity, diabetes, hypertension,
migraine, and irritable bowel syndrome.
Bipolar disorder - ANSWER-A recurrent and often chronic mental illness
marked by episodes of hypomania or mania and depression, associated
with a change or impairment in functioning.
Bipolar I and II disorders - ANSWER-These mood disorders include
mood swings that range from highs (mania) to lows (depression). It's
sometimes difficult to distinguish between bipolar disorder and
depression.
Bipolar I Disorder Criteria - ANSWER-Characterized by manic episodes,
which are distinct periods of abnormally and persistently elevated,
expansive, or irritable mood, with abnormally and persistently
increased energy or activity, lasting for at least 1 week.
Lifetime occurrence of a major depressive episode is not a requirement
for diagnosis, most people with bipolar I disorder will experience a
major depressive episode at some point during their lives.
At least 1 manic episode
Bipolar II criteria - ANSWER-Characterized by a current or past
hypomanic episode and a current or past major depressive episode.
Hypomanic episodes present with similar symptoms as mania but cause
less impairment and are of shorter duration, lasting for at least 4
consecutive days