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Pathophysiology Exam 1 Practice Problems High-Yield Questions, Answers & Review Guide

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Strengthen your understanding of Pathophysiology Exam 1 with high-yield practice problems covering cell injury, inflammation, immunity, homeostasis, and disease processes. Includes answers and explanations to support exam success and NCLEX preparation.

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Pathophysiology Exam 1 Practice Problems
Study online at https://quizlet.com/_jo40he

1. A patient is found to have liver dis- C
ease, resulting in the removal of
a lobe of his liver. Adaptation to
the reduced size of the liver leads
to ___________ of the remaining liver
cells.

A. Metaplasia
B. Organ atrophy
C. Compensatory hyperplasia
D. Physiologic hyperplasia

2. An older adult patient comes to the B, C, E
clinic complaining of not being able
to do what he used to be able to. You
know that normal changes associat-
ed with aging include: (Select all that
apply.)

A. Improved blood flow
B. Slowed metabolic rate
C. Decreased brain weight
D. Improved nerve fiber conduction
E. Less respiratory capacity

3. A 20-year-old college student has A
presented to her campus medical
clinic for a scheduled Pap smear.
The clinician who will interpret the
smear will examine cell samples for
evidence of:




, Pathophysiology Exam 1 Practice Problems
Study online at https://quizlet.com/_jo40he

A. Changes in cell shape, size, and
organization
B. Presence of unexpected cell
types
C. Ischemic changes in cell sample
D. Abnormally high numbers of cells

4. The parents of a 4-year-old girl have B
sought care because their daughter Lead -> anemia, RBC lysis
has admitted to chewing and swal-
lowing imported toy figurines that You know it's not A because there is no infection in-
have been determined to be made volved. C is focused on kidney function while D is fo-
of lead. Which of the following blood cused on liver function. Both of these would be im-
tests should the care team priori- portant in the case of lead poisoning BUT the priority
tize? answer is B, because you need first to address the
most life-threatening patient needs. The little girl in
A. White blood cell levels with differ- this question can go into shock or suffer permanent
ential organ damage if her RBCs are low.
B. Red blood cell levels and mor-
phology
C. Urea and creatinine levels
D. Liver function panel

5. A patient with severe peripheral vas- B
cular disease has developed signs
of dry gangrene on the great toe Remember that it's not C because to have gangrene,
of one foot. Which of the following you must have infection
pathophysiologic processes most
likely contributed to this diagnosis?

A. Inappropriate activation of apop-
tosis



, Pathophysiology Exam 1 Practice Problems
Study online at https://quizlet.com/_jo40he

B. Bacterial invasion
C. Impaired arterial blood supply
D. Metaplastic cellular changes

6. Although stress exposure initiates C
integrated responses by multi-
ple systems, the most important
changes are first activated by which
system?

A. Pulmonary
B. Gastrointestinal
C. Neuroendocrine
D. Cardiovascular

7. Which manifestation of stress re- D
flects the non-specific fight or flight
response? This would fall under physiologic responses to stress!!
Slide 25 in your lecture powerpoint
A. Decreased pupillary light re-
sponse
B. Increased GI motility
C. Decreased short-term memory
D. Increased cardiopulmonary rates

8. Stress-induced cortisol hormone se- B
cretion is associated with:

A. Increased growth hormone level You know it's not A because I mentioned in an earlier
B. Regulation of the stress re- slide that growth hormone levels decrease with stress.
sponse We didn't mention thyroid-stimulating hormone as
C. Increased thyroid-stimulating one of the ones associated with the stress repsonse
hormone so you can pretty much assume that's not right. And

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June 15, 2026
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