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Advanced Pathophysiology Exam 1 Study Guide High-Yield Review, Mechanisms of Disease & Practice Questions

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Prepare for Advanced Pathophysiology Exam 1 with a comprehensive study guide covering cellular injury, inflammation, immunity, genetic influences, and disease mechanisms. Includes high-yield concepts, system-based review, and practice questions for exam success.

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Advanced Pathophysiology Exam 1
Study online at https://quizlet.com/_jo417x

1. A certain disease is currently found A
in 1 of every 10 people in the
country and 1,000 people contract
the disease yearly. The population
of the country is 4,500,000. Which
of the following statements is cor-
rect?
a. The prevalence of the disease is
10% and the incidence is .02%.
b. The prevalence of the disease is
.02% and the incidence is 10%.
c. Neither is correct.
d. There is insufficient data

2. In relation to disease development, B
the term "etiology" refers to which
of the following?

a.number of people with the dis-
ease
b. cause of the disease
c. definition of the disease
d. outcome of the disease

3. Which of the following is(are) true D
about "symptoms"?
a. objective and measurable
b. the same as "signs"
c. both of the above
d. neither of the above

4. B



, Advanced Pathophysiology Exam 1
Study online at https://quizlet.com/_jo417x

In 1992, there were 980 deaths in
a Midwestern city with a population
of 1,000,000. At the beginning of
that year, 900 cases of AIDS existed
in this population. During the year,
250 new cases of AIDS were diag-
nosed, and 75 people died of the
disease in 1992.
Using the data given above, what
was the incidence rate (per 100,000
population) at the end of 1992 for
AIDS?
a. 6
b. 25
c. 88
d. 116

5. What level of prevention is a blood B
pressure screening program for
high school students who are preg-
nant?
a. primary
b. secondary
c. tertiary

6. Mr. Forbes complains of "indiges- C
tion" and becomes sweaty and pale.
His wife takes him to the Emer-
gency Department at Northwest-
ern Memorial Hospital. A cardiac
catheterization 2 days later shows
partial blockage of his right coro-


, Advanced Pathophysiology Exam 1
Study online at https://quizlet.com/_jo417x

nary artery (RCA).
Blockage of the right coronary
artery can lead to myocardial cell
injury because it results in which of
the following?
a. bilirubin accumulation in myocar-
dial cells
b. alteration in the genetic material
of myocardial cells
c. reduced energy production in
myocardial cells
d. activation of the complement
system

7. When myocardial cells are injured, A
the function of the Na-K membrane
pump may be impaired. Which of
the following may then result?
a.intracellular sodium will increase
b. extracellular potassium will de-
crease
c. cell volume will decrease
d. all of the above

8. Mr. Forbes is being prepared for A
open heart surgery when he suffers
a myocardial infarction in which a
large part of his left ventricle has
suffered lethal cell injury.
Mr. Forbes' CPK-MB and LDH1,
enzymes associated with myocar-
dial cells, are significantly elevated.


, Advanced Pathophysiology Exam 1
Study online at https://quizlet.com/_jo417x

What is the best explanation for
this?
a. It is a sign that necrotic myocar-
dial cells have released their cyto-
plasmic contents into the blood.
b. It is a sign of reversible fatty accu-
mulation in the myocardial cells
c. It is a sign that the myocardial
cells are undergoing hypertrophy.
d. None of the above.

9. If a tissue specimen of myocardial D
cells were obtained for examination
from Mr. Forbes, which of the fol-
lowing findings would indicate irre-
versible cell injury?
a. cellular swelling
b. decreased ATP production
c. decreased intracellular calcium
d. dissolution of nuclear material

10. The accumulation of lactic acid that B
occurs with impaired energy pro-
duction results from which of the
following?
a. increased intracellular glucose
b. increased anaerobic metabolism
c. decreased metabolic rate
d. increased oxidative phosphoryla-
tion

11. C

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