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1. Hypertrophy Increase in cell size - results in enlarged tissue mass
2. Causes of hyper- Additional work by the tissue
trophy Excessive hormonal stimulation
3. Examples of hy- Enlarged heart resulting from increased demands
pertrophy Effect of consistent exercise on skeletal muscle, leading to an enlarged muscle
mass
4. Atrophy Decrease in cell size - results in reduced tissue mass
5. Causes of atro- Reduced use of the tissue
phy Insufficient nutrition
Decreased neurologic or hormonal stimulation
Aging
6. Example of atro- Shrinkage of skeletal muscle that occurs when a limb is immobilized in a cast for
phy several weeks
7. Hyperplasia Increase in number of cells - results in enlarged tissue mass
8. Cause of hyper- Compensatory mechanism to meet increased demand or pathologic when there
plasia is a hormonal imbalance
, Pathophysiology (NR283) Study Guide Exam 1
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9. In some cas- Hyperplasia and hypertrophy
es ________ and
_______ can oc-
cur simultane-
ously, as in the
uterine enlarge-
ment that occurs
during pregnan-
cy
10. Metaplasia Mature cell type that is replaced by a different mature cell type
Adaptive mechanism that provides more resistance tissue
11. Example of meta- Smoker cells
plasia
12. Dysplasia Abnormal growth or development of a tissue or organ
Cells vary in size and shape within a tissue
Large nuclei are frequently present
Rate of mitosis is increased
13. Causes of dyspla- Chronic irritation
sia Infection
Precancerous change
14. Neoplasia "New growth" or tumor
15. Ischemia Deficient of oxygen in the cells
16. Most common Ischemia
cause of cell
damage
17. Hypoxia Deficiency in amount of oxygen in the tissues