ID Intro Pathophysiology
Study online at https://quizlet.com/_jo56gw
1. Helminths Worms
Eukaryotic, multi-cellular, DNA/RNA
Common in developing world
Either flatworms or nematodes
2. Fungi Eukaryotic, cellular, DNA/RNA
3. Protozoa Eukaryotic, single celled, DNA/RNA
Includes amoeba, ciliates, flagellates, and sporozoans
4. Bacteria Prokaryotic, cellular but no nucleus, DNA/RNA
Most abundant pathogen
Larger than viruses, but smaller than protozoa/fungi
Single, circular chromosome
5. Viruses Acellular, either DNA or RNA
Obligate intracellular
1/100th size of bacteria
Most abundant disease causing
6. Prion Acellular, mis-folded protein, no DNA or RNA
Obligate intracellular
7. Transmissible Caused by prions
spongiform
en-
cephalopathies
(TSE)
8. Prion pathophys- Affects neural tissue and makes it spongy by creating amyloid plaques
iology Has long incubation periods and is extremely stable
Untreatable and fatal
, ID Intro Pathophysiology
Study online at https://quizlet.com/_jo56gw
9. Prion denatura- Extremely stable, heat resistant, radiation resistant, and resistant to proteases
tion Partially denatured prions may have the ability to renature
Sterilization doesn't work
10. Viral entry Obligate intracellular, no self metabolic processes
Either endocytosis (receptor-mediated or pinocytosis) fusion, or direct penetra-
tion of cell membrane
Assemble within host cell
Some viruses are dependent on co-occurance
11. Nucleocapsid Nucleic acid (RNA or DNA) wrapped in a protein capsid in viruses
12. Envelope virus Nucleocapsid covered by an outer lipid envelope
Less stable than without envelope
Transmitted through respiratory, genital, or parenteral routes
13. Non-enveloped More stable than enveloped
virus Transmitted by fecal-oral route
14. Endocytosis Either pinocytosis or receptor mediated
One way viruses enter a host cell
Only non-enveloped viruses
Hep C
15. Fusion One way viruses enter a cell
Envelope binds to receptor, allows in, and virus breaks out
Study online at https://quizlet.com/_jo56gw
1. Helminths Worms
Eukaryotic, multi-cellular, DNA/RNA
Common in developing world
Either flatworms or nematodes
2. Fungi Eukaryotic, cellular, DNA/RNA
3. Protozoa Eukaryotic, single celled, DNA/RNA
Includes amoeba, ciliates, flagellates, and sporozoans
4. Bacteria Prokaryotic, cellular but no nucleus, DNA/RNA
Most abundant pathogen
Larger than viruses, but smaller than protozoa/fungi
Single, circular chromosome
5. Viruses Acellular, either DNA or RNA
Obligate intracellular
1/100th size of bacteria
Most abundant disease causing
6. Prion Acellular, mis-folded protein, no DNA or RNA
Obligate intracellular
7. Transmissible Caused by prions
spongiform
en-
cephalopathies
(TSE)
8. Prion pathophys- Affects neural tissue and makes it spongy by creating amyloid plaques
iology Has long incubation periods and is extremely stable
Untreatable and fatal
, ID Intro Pathophysiology
Study online at https://quizlet.com/_jo56gw
9. Prion denatura- Extremely stable, heat resistant, radiation resistant, and resistant to proteases
tion Partially denatured prions may have the ability to renature
Sterilization doesn't work
10. Viral entry Obligate intracellular, no self metabolic processes
Either endocytosis (receptor-mediated or pinocytosis) fusion, or direct penetra-
tion of cell membrane
Assemble within host cell
Some viruses are dependent on co-occurance
11. Nucleocapsid Nucleic acid (RNA or DNA) wrapped in a protein capsid in viruses
12. Envelope virus Nucleocapsid covered by an outer lipid envelope
Less stable than without envelope
Transmitted through respiratory, genital, or parenteral routes
13. Non-enveloped More stable than enveloped
virus Transmitted by fecal-oral route
14. Endocytosis Either pinocytosis or receptor mediated
One way viruses enter a host cell
Only non-enveloped viruses
Hep C
15. Fusion One way viruses enter a cell
Envelope binds to receptor, allows in, and virus breaks out
