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1. Drugs for upper 1. antihistamines
respiratory disor- 2. decongestants
der: 3. corticosteroids
4. antitussives
5. expectorants and myolytics
2. How do antihista- Block the action of histamine at the H1 receptor
mines work? (H1 receptor release histamine are allergic response)
3. What are antihist- 1. Cold symptoms - decrease nasopharyngeal secretions
amines used for? 2. Allergic rhinitis - decrease nasal itching and tickling that cause sneezing
3. Anaphylaxis
4. Drug allergies
5. Blood/blood product transfusion reaction
6. Dermatologic conditions
7. Motion sickness, nausea, vomiting, and sedation
4. Prototype of anti- diphenhydramine (Benadryl)
histamine:
5. First-generation Dry mouth and drowsiness
antihistamine
(diphenhy-
dramine,
Benadryl) cause:
6. What is Cetirizine (Zyrtec)
a second-gener- Ioratadine (Claritin)
ation antihista- ( Dont cause as much sedation as first-generation)
mines?
7. False, it can make small children excitable
, Pharmacology: Respiratory Drugs
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Benadryl does
not make chil-
dren excited. T/F
8. Benadryl can True, especially in IM or IV
cause an allergic
reaction. T/F
9. Benadryl is not False, Benadryl is also used for nausea and motion sickness.
used for nausea
or motion sick-
ness. T/F
10. Astelin (nasal True
spray) has no sys-
temic effects.
11. What is nursing 1. Caution if driving vehicle or performing tasks due to drowsiness
care for antihista- 2. Avoid alcohol and CNS depressants
mines? 3. Watch for confusion (not common), hypotension, dizziness, drowsiness, urinary
retention, blurred vision
4. Excitability in children
12. What is the mech- stimulate adrenergic receptors to cause vascular constriction of the capillaries in
anism of action the nasal mucosa
of nasal and sys-
temic deconges-
tants?
13. What is the re- Shrink nasal mucous membrane and reduce fluid secretions.
sults of a decon-
gestant?