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leaden paralysis

heavy, leaden feelings in arms or legs (atypical feature of depression)

acetylcholine and Alzheimer disease

acetylcholine is associated with attention and memory and is decreased in Alzheimer disease.

meds to help manage Alzheimer's are acetylcholinesterase inhibitors which help reduce the

breakdown of acetylcholine

dopamine and Parkinson disease

dopamine is decreased in Parkinson disease

valproate (Depakote) and neural tube defects

valproate associated with neural tube defects like spina bifida. also associated with cognitive

decline in school-age children and may increase risk of autism. folic acid taken in pregnancy

protects neural development of fetus

lamotrigine in pregnancy

associated with cleft palate

thought content

describes what type of thoughts are occurring; can be obsessive, suicidal, homicidal, delusional,

etc

thought process

, describes how thoughts are formulated, organized, and expressed; normal would be organized,

linear, and goal-directed. impaired could be: flight of ideas, circumstantiality, clang association,

derailment, neologism, perseveration, tangentiality, or thought-blocking

circumstantiality (thought process)

non-direct thinking or speech that digresses from the main point of a conversation

clang association (thought process)

association of words based on their similar sound rather than meaning

neologism (thought process)

coining new words spontaneously; words are meaningless and unrecognizable

thought blocking (thought process)

most common in schizophrenia; speech is suddenly interrupted by silences that can last seconds

to a minute or longer. when the pt starts speaking again, they will often speak about something

unrelated

s/s MAOI overdose

severe: hyperthermia, seizures, CNS depression, muscle rigidity, myoclonus

Conners Rating Scale

has parent, teacher, and self-report version to screen for ADHD; the only scale that has both

parent and teacher rating components

Hamilton Anxiety Rating Scale (HAM-A)

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