ONS ONCC CHEMOTHERAPY IMMUNOTHERAPY
2026 STUDY EXAMINERS QUESTIONS AND
ANSWERS SURE A+
✔✔Hyaluronidase
Apply warm pack for
15-20 minutes four times
daily the next 24-48
hours and keep extremity
elevated.
Administer 1 ml of hyaluronidase subcutaneously in five
separate injections, each containing 0.2 ml of the solution
using a 25 gauge or smaller needle. - ✔✔Extravasation Tx: Plant alkaloid Vinblastine,
vincristine,
vindesine,
vinorelbine
✔✔Apply ice pack for 15-20
minutes four times daily
the first 24 hours.
No known antidote - ✔✔Extravascation Tx: Taxanes Docetaxel, paclitaxe
✔✔include aching and tightness along a peripheral vein above the administration site
that occurs as the drug infuses, as well as potential redness or darkening of the vein
without swelling and ulceration. Blood return is typically present; if not, an infiltration
may have occurred - ✔✔Signs of symptoms of venous irritation:
✔✔warm compress - ✔✔Most sources recommend the application of heat using
_______________ to help reduce local discomfort and the restart of the peripheral IV in
a larger vein (Polovich et al., 2014).
, ✔✔irinotecan - ✔✔The manufacturer of ______________ recommends topical flushing
of the skin with sterile water and application of ice in the event of extravasation of the
drug (Pfizer Inc., 2012).
✔✔Burning, stinging pain around the administration site, although it is important to note
that some patients do not experience any pain with vesicant extravasation and may in
fact experience a feeling of coolness at the site (Polovich et al., 2014). -
✔✔Extravasation signs and symptoms can include
✔✔Constipation is not a likely side effect with the agents that Mrs. Turner is to receive.
Actually diarrhea is more likely when receiving both of the targeted therapies in this
regimen. - ✔✔Knowing the most common side effects of these agents (docetaxel,
carboplatin, trastuzumab and pertuzumab), which of the following side effects will you
not be covering in your patient teaching today since it is not usually seen with the
chemotherapy agents Mrs. Turner is going to receive?
✔✔ANC = (Neutrophils + Bands) x WBC / 100
To calculate the ANC:
Find the WBC, the polys/neutrophils and bands on your CBC (neutrophils can be called
many things in a differential including: polymorphonuclear cells or polys, PMNs,
granulocytes, segmented neutrophils, or segs). WBC = 2.1
Add the polys and bands (polys = 22%, bands = 4%). 22 + 4 = 26
Multiply the sum of the polys and bands by the WBC. 26 X 2.1 = 54.6
Multiply the product by 10. 54.6 X 10 = 546
Mrs. Turner's ANC is 546 - ✔✔ANC Calculation
✔✔Restriction of fresh fruits and vegetables is no longer necessary based on the
evidence (ONS PEP resource Prevention of Infection https://www.ons.org/practice-
resources/pep/prevention-infection/prevention-infection-general) - ✔✔You meet with
Mrs. Turner to discuss neutropenia and her increased risk of infections and to reinforce
with her some ways that she can prevent infections. You are familiar with the ONS PEP
resources including the resource Prevention of Infection.
You review with Mrs. Turner what the evidence recommends to prevent infections.
Which of the following is unlikely to be effective for infection prevention?
✔✔Recommended for Practice:
Adherence to General Infection Control Recommendations
Antibiotic Prophylaxis in At-Risk Patients
2026 STUDY EXAMINERS QUESTIONS AND
ANSWERS SURE A+
✔✔Hyaluronidase
Apply warm pack for
15-20 minutes four times
daily the next 24-48
hours and keep extremity
elevated.
Administer 1 ml of hyaluronidase subcutaneously in five
separate injections, each containing 0.2 ml of the solution
using a 25 gauge or smaller needle. - ✔✔Extravasation Tx: Plant alkaloid Vinblastine,
vincristine,
vindesine,
vinorelbine
✔✔Apply ice pack for 15-20
minutes four times daily
the first 24 hours.
No known antidote - ✔✔Extravascation Tx: Taxanes Docetaxel, paclitaxe
✔✔include aching and tightness along a peripheral vein above the administration site
that occurs as the drug infuses, as well as potential redness or darkening of the vein
without swelling and ulceration. Blood return is typically present; if not, an infiltration
may have occurred - ✔✔Signs of symptoms of venous irritation:
✔✔warm compress - ✔✔Most sources recommend the application of heat using
_______________ to help reduce local discomfort and the restart of the peripheral IV in
a larger vein (Polovich et al., 2014).
, ✔✔irinotecan - ✔✔The manufacturer of ______________ recommends topical flushing
of the skin with sterile water and application of ice in the event of extravasation of the
drug (Pfizer Inc., 2012).
✔✔Burning, stinging pain around the administration site, although it is important to note
that some patients do not experience any pain with vesicant extravasation and may in
fact experience a feeling of coolness at the site (Polovich et al., 2014). -
✔✔Extravasation signs and symptoms can include
✔✔Constipation is not a likely side effect with the agents that Mrs. Turner is to receive.
Actually diarrhea is more likely when receiving both of the targeted therapies in this
regimen. - ✔✔Knowing the most common side effects of these agents (docetaxel,
carboplatin, trastuzumab and pertuzumab), which of the following side effects will you
not be covering in your patient teaching today since it is not usually seen with the
chemotherapy agents Mrs. Turner is going to receive?
✔✔ANC = (Neutrophils + Bands) x WBC / 100
To calculate the ANC:
Find the WBC, the polys/neutrophils and bands on your CBC (neutrophils can be called
many things in a differential including: polymorphonuclear cells or polys, PMNs,
granulocytes, segmented neutrophils, or segs). WBC = 2.1
Add the polys and bands (polys = 22%, bands = 4%). 22 + 4 = 26
Multiply the sum of the polys and bands by the WBC. 26 X 2.1 = 54.6
Multiply the product by 10. 54.6 X 10 = 546
Mrs. Turner's ANC is 546 - ✔✔ANC Calculation
✔✔Restriction of fresh fruits and vegetables is no longer necessary based on the
evidence (ONS PEP resource Prevention of Infection https://www.ons.org/practice-
resources/pep/prevention-infection/prevention-infection-general) - ✔✔You meet with
Mrs. Turner to discuss neutropenia and her increased risk of infections and to reinforce
with her some ways that she can prevent infections. You are familiar with the ONS PEP
resources including the resource Prevention of Infection.
You review with Mrs. Turner what the evidence recommends to prevent infections.
Which of the following is unlikely to be effective for infection prevention?
✔✔Recommended for Practice:
Adherence to General Infection Control Recommendations
Antibiotic Prophylaxis in At-Risk Patients
