BUNDLE 2026 COMPLETE QUESTIONS AND
SOLUTIONS CERTIFICATION PREP
RESOURCE GRADED A+
⩥During fatty acid synthesis, after the initial step involving acetyl CoA,
the fatty acid chain is elongated by the addition of which of the
following compounds?
Answer: Malonyl CoA
⩥Excessive alcohol consumption can lead to the presentation of
hypoglycemia. This is primarily caused by which of the following?
Answer: A decrease in substrates required for gluconeogenesis
⩥What is the primary fuel oxidized in the liver (to generate ATP) in the
fasted state?
Answer: Free fatty acids
⩥The elevated levels of NADH/NAD generated by alcohol metabolism
inhibit all of the following except
Answer: Pyruvate dehydrogenase kinase
,⩥Shortly after meal high in fat you would expect an elevation of which
of the follow lipoproteins in circulation?
Answer: Chylomicrons
⩥Under fasting conditions, acetyl CoA carboxylase will be inhibited by
an increase in which of the following compounds?
Answer: Palmitoyl CoA
⩥Which of the following is consistent with an insulin/glucagon ratio of
>1?
Answer: glycogen phosphorylase, dephosphorylated, inacitve
⩥Pyruvate carboxylase is allosterically by which of the following
compounds?
Answer: Acetyl CoA
⩥Which lipoprotien is responsible for the process of reverse cholesterol
transport (the movement of cholesterol from the peripheral tissues back
to the liver)?
Answer: HDL
⩥Which of the following enzymes is responsible for the conversion of
ethanol to acetaldehyde in the cytosol?
Answer: Alcohol dehydrogenase
, ⩥Gluconeogenesis generates glucose 6-phosphate. Which of the
following is the primary fate of this compound generated by this
process?
Answer: Dephosphorylation and release into circulation
⩥Which of the following apoproteins is present on an LDL particle and
required for uptake by peripheral tissues?
Answer: ApoB100
⩥Which enzyme is responsible for transferring triacylglycerol from
VLDL to HDL in exchange for cholesterol?
Answer: CEPT (cholesterol ester transferase protein)
⩥Which of the following is the full complement of apoproteins present
on VLDLs?
Answer: ApoB100, ApoCII, ApoE
⩥What is the primary role of LCAT (Lecithin-cholesterol
acyltransferase)?
Answer: To esterify cholesterol transported by HDL