BUNDLE 2026 AUTHENTIC QUESTIONS
AND SOLUTIONS FULL REVIEW MATERIAL
GRADED A+
⩥Rotenone blocks complex 1 in the ETC. This increases levels of
NADH and would likely impair the function of which of the following
enzymes?
Answer: Pyruvate dehydrogenase complex
⩥Newborn screening shows a biotinidase deficiency in a 2-day old
infant. This deficienty impairs the infant's ability to reuse and recycle
biotin. Due to this enzymatic deficiency, the activity of which of the
following enzymes is likely impaired?
Answer: pyruvate carboxylase
⩥An individual is recently diagnosed with Type 2 diabetes. In this
individual, hyperglycemia may in part be due to inactivity of which of
the following glucose transporters on skeletal muscle?
Answer: Glut 4 (insulin dependent)
⩥The skeletal muscle primarily provides substrate for gluconeogenesis
through which of the following processes?
Answer: protein catabolism
, ⩥Alanine can be shuttled from the skeletal muscle to the liver where it is
deaminated to produce pyruvate. When glucagon is high, pyruvate is
primarily used as a substrate for which of the following pathways?
Answer: gluconeogenesis
⩥Aldolase B facilitaes a reaction that cleaves fructose 1-phosphate into
two 3-carbon molecules that will enter glycolysis as which of the
following compounds?
Answer: glyceraldehyde-3-phosphate
⩥Within the RBC, NADPH is used for which of the following
processes?
Answer: to re-reduce glutathione
⩥Galactose-1-phosphate is initially converted to glucose-1-phosphate
and requires which of the following compounds?
Answer: UDP-glucose
⩥Which of the following are the two primary products of the Pentose
Phosphate pathway?
Answer: Ribose-5-phosphate and NADPH