UAMS HEMATOLOGY FINAL PAPER 5 2026
CERTIFICATION EVALUATION QUESTIONS
AND SOLUTIONS GRADED A+
●● What stimulates WBC production?
Answer: Colony stimulating factors
●● What pool do we count for differentials?
Answer: Circulating pool
●● What are the cells located adjacent to the endothelial lining of the
vessels called?
Answer: Marginating pool
●● When are primary granules first seen?
Answer: Promyelocyte
●● What are primary or specific granules composed of?
Answer: Myeloperoxidase
●● When are secondary granules first seen?
Answer: Myelocyte
,●● What do secondary or specific granules contain?
Answer: Lysozymes
●● Granulocyte killing of organism process:
Answer: 1. Chemotaxis: move to bacteria
2. Opsonization: coat the bacteria
3. Phagocytosis: engulfs bacteria
4. Degranulation: granules fuse and discharge
5. Oxidative burst: generates H2O2
6. Kills bacteria: uses potent oxidants
7. Inflammation: damage to surrounding area
●● What WBC count is a percentage based on a total of 100 WBCs?
Answer: Relative count
●● What WBC count is the relative percentage x the total WBC count =
cells/1 uL of blood?
Answer: Absolute count
●● What is the absolute reference rage for neutrophils?
Answer: 1,700-7,500
, ●● What are some conditions where neutrophilia may be seen?
Answer: Bacterial infections, stress, inflammation, leukemias, or
pregnancy
●● What are some conditions where neutropenia may be seen?
Answer: Leukemia, chemotherapy, aplastic anemia, or infection
●● What age group has an inverse seg:lymph ratio?
Answer: Pediatric
●● Why do children have more lymphocytes than neutrophils?
Answer: Building immune system
●● How is the WBC count affected in CML?
Answer: Increased
●● How is the PLT count affected in CML?
Answer: Increased
●● What WBC is seen in high numbers with allergies, parasites or
leukemias like CML?
Answer: Eosinophil
CERTIFICATION EVALUATION QUESTIONS
AND SOLUTIONS GRADED A+
●● What stimulates WBC production?
Answer: Colony stimulating factors
●● What pool do we count for differentials?
Answer: Circulating pool
●● What are the cells located adjacent to the endothelial lining of the
vessels called?
Answer: Marginating pool
●● When are primary granules first seen?
Answer: Promyelocyte
●● What are primary or specific granules composed of?
Answer: Myeloperoxidase
●● When are secondary granules first seen?
Answer: Myelocyte
,●● What do secondary or specific granules contain?
Answer: Lysozymes
●● Granulocyte killing of organism process:
Answer: 1. Chemotaxis: move to bacteria
2. Opsonization: coat the bacteria
3. Phagocytosis: engulfs bacteria
4. Degranulation: granules fuse and discharge
5. Oxidative burst: generates H2O2
6. Kills bacteria: uses potent oxidants
7. Inflammation: damage to surrounding area
●● What WBC count is a percentage based on a total of 100 WBCs?
Answer: Relative count
●● What WBC count is the relative percentage x the total WBC count =
cells/1 uL of blood?
Answer: Absolute count
●● What is the absolute reference rage for neutrophils?
Answer: 1,700-7,500
, ●● What are some conditions where neutrophilia may be seen?
Answer: Bacterial infections, stress, inflammation, leukemias, or
pregnancy
●● What are some conditions where neutropenia may be seen?
Answer: Leukemia, chemotherapy, aplastic anemia, or infection
●● What age group has an inverse seg:lymph ratio?
Answer: Pediatric
●● Why do children have more lymphocytes than neutrophils?
Answer: Building immune system
●● How is the WBC count affected in CML?
Answer: Increased
●● How is the PLT count affected in CML?
Answer: Increased
●● What WBC is seen in high numbers with allergies, parasites or
leukemias like CML?
Answer: Eosinophil
