Chamberlain University
3 TINU • 355 NM
★ ★
C College of Nursing & Public Health
J O U R N E Y T O E X T R A O R D I N A R Y CO M PA S S I O N AT E C A R E
EST. 1889
MN 553 — Unit 3 Practice Questions
A D VA N C E D P H A R M A CO LO G Y: G I , D E R M ATO LO G Y, O P H T H A L M I C & OT I C A G E N TS
INSTITUTION Chamberlain University COURSE CODE MN 553
PROGRAM Master of Science in Nursing (MSN / FNP) ACADEMIC YEAR
UNIT Unit 3 — GI, Dermatology, Ophthalmic & TOTAL QUESTIONS 40 Questions
Otic Pharmacology
COURSE TITLE Advanced Pharmacology FORMAT Multiple Choice — Select the Single Best
Answer
EXAMINATION INSTRUCTIONS
▸ Select the single best answer for each multiple-choice question.
▸ This Unit 3 assessment covers GI pharmacology (antacids, PPIs, H2RAs, antiemetics, H. pylori treatment), dermatological agents
(antifungals, corticosteroids, acne treatments, scabies/lice), and ophthalmic/otic preparations.
▸ Correct answers and detailed rationales appear below each question.
▸ All content is aligned with Chamberlain University MN 553 Unit 3 course competencies.
GI, DERMATOLOGIC, OPHTHALMIC & OTIC PHARMACOLOGY Questions 1 – 40
1. Patients with which condition should be counseled not to take calcium carbonate antacids without discussing it
with their provider first?
A. Pregnant patients
B. Patients with heartburn
C. Patients with kidney stones
D. Postmenopausal women
CORRECT ANSWER C — Patients with kidney stones
RATIONALE Calcium carbonate antacids can increase urinary calcium excretion, potentially worsening kidney stone
formation, particularly calcium oxalate stones. Patients with a history of nephrolithiasis should consult their
provider before using calcium-containing antacids. Pregnant patients (A) may use calcium carbonate for
heartburn.
, 2. Patients taking antacids should be educated that these drugs may:
A. Cause constipation or diarrhea
B. Be high in sodium
C. Need to be separated from other medications by 1 hour
D. All of the above
CORRECT ANSWER D — All of the above
RATIONALE Antacid education must include all three points: aluminum-containing antacids cause constipation while
magnesium-containing cause diarrhea (A); many antacids contain significant sodium (B); and antacids
interfere with absorption of other medications, requiring 1–2 hour separation (C).
3. Loperamide (Imodium) is an antidiarrheal that:
A. Can be given to infants and children for viral gastroenteritis
B. Slows gastric motility and reduces fluid and electrolyte loss from diarrhea
C. Is the treatment of choice for E. coli O157 diarrhea
D. May be used in pregnancy and lactation
CORRECT ANSWER B — Slows gastric motility and reduces fluid and electrolyte loss from diarrhea
RATIONALE Loperamide is an opioid agonist that slows intestinal transit, increasing fluid/electrolyte absorption. It is
contraindicated in children under 2 years (A), should NOT be used for infectious diarrhea with fever or blood
(C—E. coli O157 risk of HUS), and is not recommended in pregnancy (D).
4. Bismuth subsalicylate (Pepto-Bismol) has which characteristics?
A. May lead to toxicity if taken with aspirin
B. Is contraindicated in children with flu-like illness (Reye's syndrome risk)
C. Has antimicrobial effects against bacterial and viral enteropathogens
D. All of the above
CORRECT ANSWER D — All of the above
RATIONALE Bismuth subsalicylate contains salicylate—toxicity risk with concurrent aspirin (A). It is contraindicated in
children with viral illness due to Reye's syndrome risk (B). It has direct antimicrobial effects (C). For traveler's
diarrhea prevention, it is taken with each meal and at bedtime.
5. For traveler's diarrhea prevention, Hannah should be advised to take:
A. Loperamide four times daily throughout the trip
B. Bismuth subsalicylate with each meal and at bedtime
C. A prescription for diphenoxylate with atropine to use if she gets diarrhea
D. None of the above
CORRECT ANSWER B — Bismuth subsalicylate with each meal and at bedtime
RATIONALE Bismuth subsalicylate provides up to 65% protection against traveler's diarrhea when taken prophylactically
(2 tablets or 2 oz liquid four times daily—with meals and at bedtime). Loperamide (A) is treatment, not
prevention. Prophylactic antibiotics are reserved for high-risk travelers.
3 TINU • 355 NM
★ ★
C College of Nursing & Public Health
J O U R N E Y T O E X T R A O R D I N A R Y CO M PA S S I O N AT E C A R E
EST. 1889
MN 553 — Unit 3 Practice Questions
A D VA N C E D P H A R M A CO LO G Y: G I , D E R M ATO LO G Y, O P H T H A L M I C & OT I C A G E N TS
INSTITUTION Chamberlain University COURSE CODE MN 553
PROGRAM Master of Science in Nursing (MSN / FNP) ACADEMIC YEAR
UNIT Unit 3 — GI, Dermatology, Ophthalmic & TOTAL QUESTIONS 40 Questions
Otic Pharmacology
COURSE TITLE Advanced Pharmacology FORMAT Multiple Choice — Select the Single Best
Answer
EXAMINATION INSTRUCTIONS
▸ Select the single best answer for each multiple-choice question.
▸ This Unit 3 assessment covers GI pharmacology (antacids, PPIs, H2RAs, antiemetics, H. pylori treatment), dermatological agents
(antifungals, corticosteroids, acne treatments, scabies/lice), and ophthalmic/otic preparations.
▸ Correct answers and detailed rationales appear below each question.
▸ All content is aligned with Chamberlain University MN 553 Unit 3 course competencies.
GI, DERMATOLOGIC, OPHTHALMIC & OTIC PHARMACOLOGY Questions 1 – 40
1. Patients with which condition should be counseled not to take calcium carbonate antacids without discussing it
with their provider first?
A. Pregnant patients
B. Patients with heartburn
C. Patients with kidney stones
D. Postmenopausal women
CORRECT ANSWER C — Patients with kidney stones
RATIONALE Calcium carbonate antacids can increase urinary calcium excretion, potentially worsening kidney stone
formation, particularly calcium oxalate stones. Patients with a history of nephrolithiasis should consult their
provider before using calcium-containing antacids. Pregnant patients (A) may use calcium carbonate for
heartburn.
, 2. Patients taking antacids should be educated that these drugs may:
A. Cause constipation or diarrhea
B. Be high in sodium
C. Need to be separated from other medications by 1 hour
D. All of the above
CORRECT ANSWER D — All of the above
RATIONALE Antacid education must include all three points: aluminum-containing antacids cause constipation while
magnesium-containing cause diarrhea (A); many antacids contain significant sodium (B); and antacids
interfere with absorption of other medications, requiring 1–2 hour separation (C).
3. Loperamide (Imodium) is an antidiarrheal that:
A. Can be given to infants and children for viral gastroenteritis
B. Slows gastric motility and reduces fluid and electrolyte loss from diarrhea
C. Is the treatment of choice for E. coli O157 diarrhea
D. May be used in pregnancy and lactation
CORRECT ANSWER B — Slows gastric motility and reduces fluid and electrolyte loss from diarrhea
RATIONALE Loperamide is an opioid agonist that slows intestinal transit, increasing fluid/electrolyte absorption. It is
contraindicated in children under 2 years (A), should NOT be used for infectious diarrhea with fever or blood
(C—E. coli O157 risk of HUS), and is not recommended in pregnancy (D).
4. Bismuth subsalicylate (Pepto-Bismol) has which characteristics?
A. May lead to toxicity if taken with aspirin
B. Is contraindicated in children with flu-like illness (Reye's syndrome risk)
C. Has antimicrobial effects against bacterial and viral enteropathogens
D. All of the above
CORRECT ANSWER D — All of the above
RATIONALE Bismuth subsalicylate contains salicylate—toxicity risk with concurrent aspirin (A). It is contraindicated in
children with viral illness due to Reye's syndrome risk (B). It has direct antimicrobial effects (C). For traveler's
diarrhea prevention, it is taken with each meal and at bedtime.
5. For traveler's diarrhea prevention, Hannah should be advised to take:
A. Loperamide four times daily throughout the trip
B. Bismuth subsalicylate with each meal and at bedtime
C. A prescription for diphenoxylate with atropine to use if she gets diarrhea
D. None of the above
CORRECT ANSWER B — Bismuth subsalicylate with each meal and at bedtime
RATIONALE Bismuth subsalicylate provides up to 65% protection against traveler's diarrhea when taken prophylactically
(2 tablets or 2 oz liquid four times daily—with meals and at bedtime). Loperamide (A) is treatment, not
prevention. Prophylactic antibiotics are reserved for high-risk travelers.
