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NR 324 Exam 1 Study Guide 2026 | 250+ Questions and Answers | Fluid & Electrolyte Balance, Acid-Base Disorders, Respiratory Nursing, ABGs, COPD, Asthma & Pneumonia | Chamberlain University

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This comprehensive NR 324 Exam 1 study guide contains more than 250 exam-focused questions, answers, clinical scenarios, illustrations, and nursing rationales covering the core concepts of adult health nursing related to fluid and electrolyte balance, acid-base regulation, respiratory assessment, and respiratory disorders. Designed for Chamberlain University NR 324 students, this resource provides detailed preparation for Exam 1 through a combination of practice questions, laboratory value interpretation, nursing interventions, priority assessments, and clinical application exercises. The material offers extensive coverage of arterial blood gas (ABG) interpretation, including respiratory acidosis, respiratory alkalosis, metabolic acidosis, and metabolic alkalosis. Students will review normal laboratory values, compensation mechanisms, causes, signs and symptoms, diagnostic findings, and evidence-based nursing interventions for acid-base imbalances. The guide also explores fluid volume deficit, fluid volume excess, dehydration, hypernatremia, hyponatremia, hyperkalemia, hypokalemia, hypercalcemia, hypocalcemia, magnesium disorders, phosphorus imbalances, and intravenous fluid therapy, including isotonic, hypotonic, and hypertonic solutions. A major focus of this review is respiratory nursing care, including oxygenation, ventilation, gas exchange, respiratory assessment, abnormal lung sounds, oxygen delivery systems, chest tubes, thoracentesis, tracheostomy care, and pulmonary diagnostics. High-yield disease processes include asthma, chronic obstructive pulmonary disease (COPD), pneumonia, tuberculosis, pulmonary embolism, pneumothorax, pleural effusion, atelectasis, aspiration pneumonia, and obstructive sleep apnea (OSA). Each topic emphasizes nursing priorities, patient assessment findings, pharmacologic management, patient education, and NCLEX-style clinical judgment. The content aligns with evidence-based concepts commonly presented in adult health nursing curricula and major nursing references, including Lewis's Medical-Surgical Nursing and Brunner & Suddarth's Textbook of Medical-Surgical Nursing. Particular emphasis is placed on clinical reasoning, prioritization, interpretation of laboratory findings, recognition of life-threatening complications, and implementation of safe nursing interventions for patients experiencing respiratory and electrolyte disturbances. This document is particularly valuable for students preparing for NR 324 Exam 1, Adult Health Nursing examinations, HESI Medical-Surgical assessments, ATI Adult Medical-Surgical examinations, and NCLEX-RN preparation. The organized question-and-answer format allows learners to rapidly identify knowledge gaps, reinforce critical concepts, and improve test-taking confidence while mastering essential medical-surgical nursing content. Relevant for: Chamberlain University Nursing Students NR 324 Adult Health Nursing Students Medical-Surgical Nursing Students BSN Students ADN Students Practical Nursing Students HESI Preparation Students ATI Adult Medical-Surgical Students NCLEX-RN Candidates Clinical Nursing Students Acute Care Nursing Students Adult Health Assessment Students Respiratory Nursing Students Fluid and Electrolyte Nursing Students Keywords: fluid and electrolyte balance, acid base balance, arterial blood gases, ABG interpretation, respiratory acidosis, respiratory alkalosis, metabolic acidosis, metabolic alkalosis, hypernatremia, hyponatremia, hyperkalemia, hypokalemia, hypercalcemia, hypocalcemia, hypermagnesemia, hypomagnesemia, phosphorus imbalance, fluid volume deficit, fluid volume excess, dehydration, intravenous fluids, isotonic solutions, hypotonic solutions, hypertonic solutions, oxygenation, ventilation, gas exchange, respiratory assessment, abnormal lung sounds, crackles, wheezes, rhonchi, asthma, COPD, chronic obstructive pulmonary disease, pneumonia, aspiration pneumonia, tuberculosis, pulmonary embolism, pneumothorax, pleural effusion, atelectasis, chest tube management, thoracentesis, tracheostomy care, oxygen therapy, nonrebreather mask, Venturi mask, respiratory disorders, adult health nursing, medical surgical nursing, nursing exam questions, nursing study guide, clinical judgment, nursing interventions, NCLEX preparation, HESI review, ATI exam preparation, Chamberlain University, NR324 Exam 1

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NR 324 Exam 1 Fluid and
Electrolytes and Respiratory
2026 Exam All Answers and
Illustrations Given



paO2 - ANSWER ✔✔80-100 mm Hg


pH - ANSWER ✔✔7.35-7.45


low pH - ANSWER ✔✔acidic


high pH - ANSWER ✔✔alkalosis


pa CO2 - ANSWER ✔✔35-45 mm Hg

,HCO3 - ANSWER ✔✔22-26 mEq/L


respiratory acidosis - ANSWER ✔✔low pH, high co2, normal

bicarbonate


causes of respiratory acidosis - ANSWER ✔✔respiratory depression

from anesthesia, overdose, increased intracranial pressure, airway

obstruction from decreased alveolar capillary diffusion like pneumonia,

COPD, ARDS, AND PE


signs/symptoms of respiratory acidosis - ANSWER

✔✔hypoventilation (hypoxia), rapid, shallow respirations, decrease in

BP, skin/mucous pale to cyanotic, headache, hyperkalemia,

dysrhythmias, drowsiness, dizziness, disorientation, muscle weakness,

hyperreflexia


Nursing management of respiratory acidosis - ANSWER

✔✔ventilator, arterial blood gas, low-dose oxygen in chronic conditions,

high-dose oxygen in acute hypoxia with acidosis, I/O, promote the

release of CO2, turn/cough/deep breathe, assume semi-high fowlers

position, clear respiratory secretions, colors of skin, mucous membranes


respiratory alkalosis - ANSWER ✔✔high pH, low co2 and normal

bicarbonate

, causes of respiratory alkalosis - ANSWER ✔✔high pH, low co2 and

hyperventilation, initial stages of pulmonary emboli, hypoxia, fever,

pregnancy, high altitudes, and anxiety


signs/symptoms of respiratory alkalosis - ANSWER ✔✔seizures,

deep/rapid breathing, hyperventilation, tachycardia, decrease BP,

hypokalemia, numbness/tingling in extremities, lethargy/confusion, light

headedness, N/V


nursing management of respiratory alkalosis - ANSWER ✔✔kidneys

retain H+ ions, use a rebreather mask or paper bag, sedatives, monitor

respiratory rate/depth, tachycardia, low BP, serum K+ levels/ECG levels,

hydration status I/O, check for toxicities


metabolic acidosis - ANSWER ✔✔low ph, normal co2 and low

bicarbonate


metabolic acidosis signs/symptoms - ANSWER ✔✔compensatory

hyperventilation (kussmaul respirations), headache, decreased BP,

hyperkalemia, muscle twitching, warm/flushed skin, N/D/V, changes in

LOC,


causes of metabolic acidosis - ANSWER ✔✔low ph/low bicarbonate,

diabetic ketoacidosis, shock, sepsis, severe diarrhea, and renal failure



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