NR 566 ADVANCED PHARMACOLOGY FOR CARE OF THE FAMILY
NR566 MIDTERM EXAM| MIDTERM EXAM|250
Qs&As |ALREADY GRADED A+
Which non-amphetamines are FDA approved for weight loss that have lower
abuse risk?
Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss?
-Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by
increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines?
3 months or less
What drug schedule are Phentermine and Diethylpropion under?
Schedule IV
,NR 566 ADVANCED PHARMACOLOGY FOR CARE OF THE FAMILY
What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for?
-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects
-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss?
Increases satiety
What are some Phentermine/topiramate contraindications for use?
not approved in children and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid
insomnia?
given before 1600
,NR 566 ADVANCED PHARMACOLOGY FOR CARE OF THE FAMILY
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution?
hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects
insomnia, nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply.
A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%.
, NR 566 ADVANCED PHARMACOLOGY FOR CARE OF THE FAMILY
GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins
that may not be absorbed well when taking Orlistat.
2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
12
Orlistat results in the least amount of weight loss of all. How much?
2-3% body weight (7 lbs in year)
Orlistat adverse effects
Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage
(light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated?
In those with malabsorption syndrome or cholestasis
NR566 MIDTERM EXAM| MIDTERM EXAM|250
Qs&As |ALREADY GRADED A+
Which non-amphetamines are FDA approved for weight loss that have lower
abuse risk?
Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss?
-Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by
increasing the availability of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines?
3 months or less
What drug schedule are Phentermine and Diethylpropion under?
Schedule IV
,NR 566 ADVANCED PHARMACOLOGY FOR CARE OF THE FAMILY
What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for?
-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects
-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss?
Increases satiety
What are some Phentermine/topiramate contraindications for use?
not approved in children and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid
insomnia?
given before 1600
,NR 566 ADVANCED PHARMACOLOGY FOR CARE OF THE FAMILY
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution?
hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects
insomnia, nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply.
A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%.
, NR 566 ADVANCED PHARMACOLOGY FOR CARE OF THE FAMILY
GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins
that may not be absorbed well when taking Orlistat.
2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
12
Orlistat results in the least amount of weight loss of all. How much?
2-3% body weight (7 lbs in year)
Orlistat adverse effects
Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage
(light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated?
In those with malabsorption syndrome or cholestasis
